Outputs (559)

Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study (2021)
Journal Article
Hippisley-Cox, J., Patone, M., Mei, X. W., Saatci, D., Dixon, S., Khunti, K., Zaccardi, F., Watkinson, P., Shankar-Hari, M., Doidge, J., Harrison, D. A., Griffin, S. J., Sheikh, A., & Coupland, C. A. C. (2021). Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study. BMJ, 374, Article n1931. https://doi.org/10.1136/bmj.n1931

Objective: To assess the association between covid-19 vaccines and risk of thrombocytopenia and thromboembolic events in England among adults.

Design: Self-controlled case series study using national data on covid-19 vaccination and hospital adm... Read More about Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study.

Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD) (2021)
Journal Article
Khawagi, W. Y., Steinke, D., Carr, M. J., Wright, A. K., Ashcroft, D. M., Avery, A., & Neil Keers, R. (2022). Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD). BMJ Quality and Safety, 31(5), 364-378. https://doi.org/10.1136/bmjqs-2021-013427

Background: Most patients with mental illness are managed in primary care, yet there is a lack of data exploring potential prescribing safety issues in this setting for this population.

Objectives: Examine the prevalence of, between-practice var... Read More about Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD).

Sex disparity in subsequent outcomes in survivors of coronary heart disease (2021)
Journal Article
Akyea, R. K., Kontopantelis, E., Kai, J., Weng, S. F., Patel, R. S., Asselbergs, F. W., & Qureshi, N. (2022). Sex disparity in subsequent outcomes in survivors of coronary heart disease. Heart, 108(1), 37-45. https://doi.org/10.1136/heartjnl-2021-319566

Objective: Evidence on sex differences in outcomes after developing coronary heart disease (CHD) has focused on recurrent CHD, all-cause mortality or revascularisation. We assessed sex disparities in subsequent major adverse cardiovascular events (M... Read More about Sex disparity in subsequent outcomes in survivors of coronary heart disease.

Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy (2021)
Journal Article
Slaich, B., Claire, R., Emery, J., Lewis, S., Cooper, S., Thomson, R., Phillips, L., Kinahan-Goodwin, D., Naughton, F., McDaid, L., Clark, M., Dickinson, A., & Coleman, T. (2022). Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy. Addiction, 117(3), 751-759. https://doi.org/10.1111/add.15671

Background and Aims
Although English Stop Smoking Services routinely offer dual nicotine replacement therapy (NRT) to help pregnant women quit smoking, little is known about how nicotine and tobacco smoke exposures following this compares with that... Read More about Comparison of saliva cotinine and exhaled carbon monoxide concentrations when smoking and after being offered dual nicotine replacement therapy in pregnancy.

Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study (2021)
Journal Article
Pollock, K., Wilson, E., Caswell, G., Latif, A., Caswell, A., Avery, A., Anderson, C., Crosby, V., & Faul, C. (2021). Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study. Health Services and Delivery Research, 9(14), 1-162. https://doi.org/10.3310/hsdr09140

Background
More effective ways of managing symptoms of chronic and terminal illness enable patients to be cared for, and to die, at home. This requires patients and family caregivers to manage complex medicines regimens, including powerful painkille... Read More about Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study.

Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper (2021)
Journal Article
Ranger, T. A., Burchardt, J., Clift, A. K., Mei, W. X., Coupland, C., Tan, P. S., Dixon, S., Cardwell, C. R., & Hippisley-Cox, J. (2021). Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper. BMJ Open, 11(8), Article e046701. https://doi.org/10.1136/bmjopen-2020-046701

Introduction Hormone replacement therapy (HRT) can help women experiencing menopausal symptoms, but usage has declined due to uncertainty around risks of cancer and some cardiovascular diseases (CVD). Moreover, improved cancer survival rates mean tha... Read More about Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper.

Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial (2021)
Journal Article
Ussher, M., Best, C., Lewis, S., McKell, J., Coleman, T., Cooper, S., Orton, S., & Bauld, L. (2021). Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial. Trials, 22(1), Article 512. https://doi.org/10.1186/s13063-021-05480-6

Background: Financial incentives are an effective way of helping women to stop smoking during pregnancy. Unfortunately, most women who stop smoking at this time return to smoking within 12 months of the infant’s birth. There is no evidence for interv... Read More about Financial Incentives for Preventing Postpartum return to Smoking (FIPPS): study protocol for a three-arm randomised controlled trial.

Using chart online comparative analysis service to support the national rollout of PINCER (2021)
Presentation / Conference Contribution
Rodgers, S., Barrett, J., Oliver, K., Fensome, L., Johnson, J., Panayiotidis, T., Avery, A. J., & Smithson, O. Using chart online comparative analysis service to support the national rollout of PINCER. Presented at PRIMM 32nd Annual Scientific Meeting, 11 June 2021: Big Data: Is it the Future of Medicines Optimisation?, Virtual

Pharmacogenomic testing to support prescribing in primary care: A structured review of implementation models (2021)
Journal Article
Hayward, J., McDermott, J., Qureshi, N., & Newman, W. (2021). Pharmacogenomic testing to support prescribing in primary care: A structured review of implementation models. Pharmacogenomics, 22(12), 761-777. https://doi.org/10.2217/pgs-2021-0032

The application of pharmacogenomics could meaningfully contribute toward medicines optimization within primary care. This review identified 13 studies describing eight implementation models utilizing a multi-gene pharmacogenomic panel within a primar... Read More about Pharmacogenomic testing to support prescribing in primary care: A structured review of implementation models.

Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder (2021)
Journal Article
Tyrrell, E., & Prasad, V. (2021). Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder. Paediatrics and Child Health, 31(10), 371-375. https://doi.org/10.1016/j.paed.2021.07.001

Injuries among children and young people are a leading cause of morbidity and mortality in the UK and globally. Attention-deficit/hyperactivity disorder (ADHD) is an important neurodevelopmental disorder which can be present from preschool age but is... Read More about Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder.