Outputs (95)

Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes (2020)
Journal Article
Jarrold, K., Helfer, B., Eskander, M., Crawley, H., Trabulsi, J., Caulfield, L. E., Duffy, G., Garcia-Larsen, V., Hayward, D., Hyde, M., Jeffries, S., Knip, M., Leonardi-Bee, J., Loder, E., Lodge, C. J., Lowe, A. J., McGuire, W., Osborn, D., Przyrembel, H., Renfrew, M. J., …Boyle, R. J. (2020). Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes. JAMA Pediatrics, 174(9), 874-881. https://doi.org/10.1001/jamapediatrics.2020.0578

Importance: Breast milk substitutes (BMS) are important nutritional products evaluated in clinical trials. Concerns have been raised about the risk of bias in BMS trials, the reliability of claims that arise from such trials, and the potential for B... Read More about Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes.

Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study (2020)
Journal Article
Tan, S., Szatkowski, L., Moreton, W., Fiaschi, L., McKeever, T., Gibson, J., & Sharkey, D. (2020). Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study. European Respiratory Journal, 56(1), Article 2000202. https://doi.org/10.1183/13993003.00202-2020

Background Globally, bronchopulmonary dysplasia (BPD) continues to increase in preterm infants. Recent studies exploring subsequent early childhood respiratory morbidity have been small or focused on hospital admissions.

Primary aim Examine early... Read More about Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study.

Content, structure, and delivery characteristics of yoga interventions for managing hypertension: A systematic review protocol (2020)
Journal Article
Nalbant, G., Lewis, S., & Chattopadhyay, K. (2020). Content, structure, and delivery characteristics of yoga interventions for managing hypertension: A systematic review protocol. International Journal of Yoga, 13(2), 111-114. https://doi.org/10.4103/ijoy.ijoy_88_19

Aims: This systematic review aims to summarize the content, structure and delivery characteristics of yoga interventions used for managing hypertension.

Introduction: Globally, hypertension-related morbidity and mortality are high. Yoga might be... Read More about Content, structure, and delivery characteristics of yoga interventions for managing hypertension: A systematic review protocol.

Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study (2020)
Journal Article
Young, B., Fogarty, A. W., Skelly, R., Shaw, D., Sturrock, N., Norwood, M., Thurley, P., Lewis, S., Langley, T., & Cranwell, J. (2020). Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study. BMC Medical Informatics and Decision Making, 20(1), 80. https://doi.org/10.1186/s12911-020-1087-2

BACKGROUND: Avoidable use of diagnostic tests can both harm patients and increase the cost of healthcare. Nudge-type educational interventions have potential to modify clinician behaviour while respecting clinical autonomy and responsibility, but the... Read More about Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study.

Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol (2020)
Other
Docherty, A. B., Harrison, E. M., Green, C. A., Hardwick, H. E., Pius, R., Norman, L., Holden, K. A., Read, J. M., Dondelinger, F., Carson, G., Merson, L., Lee, J., Plotkin, D., Sigfrid, L., Halpin, S., Jackson, C., Gamble, C., Horby, P. W., Nguyen-Van-Tam, J. S., Dunning, J., …Semple, M. G. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol

Objective: To characterize the clinical features of patients with severe COVID-19 in the UK. Design: Prospective observational cohort study with rapid data gathering and near real-time analysis, using a pre-approved questionnaire adopted by the WHO.... Read More about Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol.

Spatial geochemistry influences the home range of elephants (2020)
Journal Article
Sach, F., Yon, L., Henley, M. D., Bedetti, A., Buss, P., de Boer, W. F., Dierenfeld, E. S., Gardner, A., Langley-Evans, S. C., Hamilton, E., Lark, R. M., Prins, H. H. T., Swemmer, A. M., & Watts, M. J. (2020). Spatial geochemistry influences the home range of elephants. Science of the Total Environment, 729, Article 139066. https://doi.org/10.1016/j.scitotenv.2020.139066

© 2020 Elsevier B.V. The unique geochemistry surrounding the Palabora Mining Company (PMC) land may act as a micronutrient hotspot, attracting elephants to the area. The PMC produces refined copper and extracts phosphates and other minerals. Understa... Read More about Spatial geochemistry influences the home range of elephants.

Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching (2020)
Journal Article
Morgan, L., McKeever, T. M., Nightingale, J., Deakin, D. E., & Moppett, I. K. (2020). Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching. Anaesthesia, 75(9), 1173-1179. https://doi.org/10.1111/anae.15042

Around 76,000 people fracture their hip annually in the UK at a considerable personal, social and financial cost. Despite longstanding debate, the optimal mode of anaesthesia (general or spinal) remains unclear. Our aim was to assess whether there is... Read More about Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching.

The effect of tobacco and alcohol consumption on poverty in the UK (2020)
Journal Article
Nyakutsikwa, B., Britton, J., & Langley, T. (2021). The effect of tobacco and alcohol consumption on poverty in the UK. Addiction, 116(1), 150-158. https://doi.org/10.1111/add.15096

Background and Aims: Tobacco and alcohol use are major risk factors for premature mortality and morbidity. Tobacco and alcohol expenditure may also exacerbate poverty. This study aimed to estimate the financial impact of tobacco and alcohol consumpti... Read More about The effect of tobacco and alcohol consumption on poverty in the UK.

Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium (2020)
Journal Article
Portelli, M. A., Dijk, F. N., Ketelaar, M. E., Shrine, N., Hankinson, J., Bhaker, S., Grotenboer, N. S., Obeidat, M., Henry, A. P., Billington, C. K., Shaw, D., Johnson, S. R., Pogson, Z. E., Fogarty, A., McKeever, T. M., Nickle, D. C., Bossé, Y., van den Berge, M., Faiz, A., Brouwer, S., …Sayers, I. (2020). Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI insight, 5(8), Article 132446. https://doi.org/10.1172/jci.insight.132446

The IL1RL1 (ST2) gene locus is robustly associated with asthma; however, the contribution of single nucleotide polymorphisms (SNPs) in this locus to specific asthma subtypes and the functional mechanisms underlying these associations remain to be def... Read More about Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.

Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study (2020)
Journal Article
Suárez-Medina, R., Venero-Fernández, S., Alvarez-Valdés, V., Sardiñas-Baez, N., Cristina, C., Loinaz-Gonzalez, M., Verdecia-Pérez, Z., Corona-Tamayo, B., Betancourt-López, M., Britton, J., & Fogarty, A. W. (2020). Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study. BMJ Open, 10(4), Article e034192. https://doi.org/10.1136/bmjopen-2019-034192

Objectives: Asthma has not been extensively studied in low-income and middle-income countries, where risk factors and access to treatment may differ from more affluent countries. We aimed to identify the prevalence of asthma and local risk factors in... Read More about Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study.