Outputs (485)

Paternal periconception metabolic health and offspring programming (2021)
Journal Article
Eid, N., Morgan, H. L., & Watkins, A. J. (2021). Paternal periconception metabolic health and offspring programming. Proceedings of the Nutrition Society, https://doi.org/10.1017/S0029665121003736

The association between maternal metabolic status at the time of conception and subsequent embryogenesis and offspring development has been studied in detail. However, less attention has been given to the significance of paternal nutrition and metabo... Read More about Paternal periconception metabolic health and offspring programming.

Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis (2021)
Journal Article
Giesbers, S., Goh, E., Kew, T., Allotey, J., Brizuela, V., Kara, E., …Mofenson, L. (2021). Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology, 267, 120-128. https://doi.org/10.1016/j.ejogrb.2021.10.007

Objective: Clinical trials evaluating pharmacological and non-pharmacological treatment of COVID-19, either excluded pregnant women or included very few women. Unlike the numerous systematic reviews on prevalence, symptoms and adverse outcomes of COV... Read More about Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis.

Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging (2021)
Journal Article
Martinez De La Cruz, B., Markus, R., Malla, S., Haig, M. I., Gell, C., Sang, F., …Knight, H. M. (2021). Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging. Molecular Psychiatry, 26(12), 7141-7153. https://doi.org/10.1038/s41380-021-01282-z

Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapse... Read More about Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging.

Feasibility of Photodynamic Therapy for Glioblastoma with the Mitochondria-Targeted Photosensitizer Tetramethylrhodamine Methyl Ester (TMRM) (2021)
Journal Article
Vasilev, A., Sofi, R., Smith, S. J., Rahman, R., Teschemacher, A. G., & Kasparov, S. (2021). Feasibility of Photodynamic Therapy for Glioblastoma with the Mitochondria-Targeted Photosensitizer Tetramethylrhodamine Methyl Ester (TMRM). Biomedicines, 9(10), Article 1453. https://doi.org/10.3390/biomedicines9101453

One of the most challenging problems in the treatment of glioblastoma (GBM) is the highly infiltrative nature of the disease. Infiltrating cells that are non-resectable are left behind after debulking surgeries and become a source of regrowth and rec... Read More about Feasibility of Photodynamic Therapy for Glioblastoma with the Mitochondria-Targeted Photosensitizer Tetramethylrhodamine Methyl Ester (TMRM).

Use of pooled serum samples to assess herd disease status using commercially available ELISAs (2021)
Journal Article
Hernandez-Medrano, J. H., Fernando Espinosa-Castilloa, L., Rodrigueza, A. D., Gutierreza, C. G., & Wapenaar, W. (2021). Use of pooled serum samples to assess herd disease status using commercially available ELISAs. Tropical Animal Health and Production, 53(5), Article 507. https://doi.org/10.1007/s11250-021-02939-1

Pooled samples are used in veterinary and human medicine as a cost-effective approach to monitor disease prevalence. Nonetheless, there is limited information on the effect of pooling on test performance, and research is required to determine the app... Read More about Use of pooled serum samples to assess herd disease status using commercially available ELISAs.

A Systematic Review of the Biological Effects of Cordycepin (2021)
Journal Article
Radhi, M., Ashraf, S., Lawrence, S., Tranholm, A. A., Wellham, P. A. D., Hafeez, A., …De Moor, C. H. (2021). A Systematic Review of the Biological Effects of Cordycepin. Molecules, 26(19), Article 5886. https://doi.org/10.3390/molecules26195886

We conducted a systematic review of the literature on the effects of cordycepin on cell survival and proliferation, inflammation, signal transduction and animal models. A total of 1204 publications on cordycepin were found by the cut-off date of 1 Fe... Read More about A Systematic Review of the Biological Effects of Cordycepin.

Exploring the challenges of accessing medication for patients with cystic fibrosis (2021)
Journal Article
Herbert, S., Rowbotham, N., Smith, S., Wilson, P., Elliott, Z., Leighton, P., …Smyth, A. R. (2022). Exploring the challenges of accessing medication for patients with cystic fibrosis. Thorax, 77(3), 295-297. https://doi.org/10.1136/thoraxjnl-2021-217140

Reducing treatment burden in cystic fibrosis (CF) is the top research priority for patients and clinicians. Difficulty accessing medication is one aspect of treatment burden. We investigated this with an online survey available globally for patients... Read More about Exploring the challenges of accessing medication for patients with cystic fibrosis.

Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions (2021)
Journal Article
O’Toole, G. A., Crabbé, A., Kümmerli, R., LiPuma, J. J., Bomberger, J. M., Davies, J. C., …Whiteson, K. (2021). Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions. mBio, 12(5), https://doi.org/10.1128/mbio.01763-21

A recent workshop titled “Developing Models to Study Polymicrobial Infections,” sponsored by the Dartmouth Cystic Fibrosis Center (DartCF), explored the development of new models to study the polymicrobial infections associated with the airways of pe... Read More about Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions.

Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology (2021)
Journal Article
Venkatanarayanan, N., & Walker, K. F. (2021). Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology. Best Practice and Research: Clinical Obstetrics and Gynaecology, 77, 42-52. https://doi.org/10.1016/j.bpobgyn.2021.08.007

Worldwide, there has been a trend toward later motherhood. Concurrently, the incidence of subfertility has been on the rise, necessitating conception using assisted reproductive technologies (ARTs). These pregnancies are considered high risk due to f... Read More about Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology.

Telehealth after the pandemic: Will the inverse care law apply? (Commentary) (2021)
Journal Article
Calthorpe, R. J., & Smyth, A. R. (2021). Telehealth after the pandemic: Will the inverse care law apply? (Commentary). Journal of Cystic Fibrosis, 20, 47-48. https://doi.org/10.1016/j.jcf.2021.08.023

The COVID-19 pandemic has accelerated the use of telehealth within the cystic fibrosis (CF) community to deliver CF care. The article by Solomon and colleagues exploring the patient and family experiences of telehealth care delivery, as part of the C... Read More about Telehealth after the pandemic: Will the inverse care law apply? (Commentary).