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Outputs (12)

Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles (2020)
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Jain, A., Trindade, G., Hicks, J. M., Potts, J. C., Rahman, R., Hague, R., …Rawson, F. Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles

Protein orientation in nanoparticle-protein conjugates plays a crucial role in binding to cell receptors and ultimately, defines their targeting efficiency. Therefore, understanding fundamental aspects of the role of protein orientation upon adsorpti... Read More about Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles.

Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review. (2020)
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Marsh, R. J., Ng, C., Major, G., Rivett, D. W., Smyth, A. R., & Gast, C. V. D. Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review

Background Patients with cystic fibrosis (CF) are characterised by abnormalities of the intestinal tract relating to gut motility and physiological issues, with daily symptoms of disease including abdominal pain, flatulence, bloating, and constipatio... Read More about Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review..

An ex vivocystic fibrosis model recapitulates key clinical aspects of chronic Staphylococcus aureus infection (2019)
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Sweeney, E., Hassan, M. M., Harrington, N. E., Smyth, A. R., Hurley, M. N., Tormo-Mas, M. Á., & Harrison, F. (2019). An ex vivocystic fibrosis model recapitulates key clinical aspects of chronic Staphylococcus aureus infection

Staphylococcus aureus is one of the most prevalent organisms isolated from the airways of people with cystic fibrosis (CF), predominantly early in life. Yet its role in the pathology of lung disease is poorly understood. Clinical studies are limited... Read More about An ex vivocystic fibrosis model recapitulates key clinical aspects of chronic Staphylococcus aureus infection.

Working with the patient and clinical community to deliver clinical research in cystic fibrosis: James Lind CF Phase II (2018)
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Smith, S., Rowbotham, N. J., & Smyth, A. R. (2018). Working with the patient and clinical community to deliver clinical research in cystic fibrosis: James Lind CF Phase II. London

This is a protocol which sets out the aims, objectives and commitments of the second phase of the James Lind Alliance Priority Setting Partnership in Cystic Fibrosis and the basic roles and responsibilities of the partners therein. The James Lind... Read More about Working with the patient and clinical community to deliver clinical research in cystic fibrosis: James Lind CF Phase II.

Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis
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Hurley, M., Smyth, A. R., Fogarty, A. W., McKeever, T. M., Rosenfeld, M., & Goss, C. (2016). Research Protocol - Effect of anti-staphylococcal antibiotic prophylaxis upon isolation and colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and their resistant variants in cystic fibrosis