Outputs (105)

Emollient bath additives for the treatment of childhood eczema (BATHE): multi-centre pragmatic parallel group randomised controlled trial of clinical and cost-effectiveness (2018)
Journal Article
Santer, M., Ridd, M. J., Francis, N. A., Stuart, B., Rumsby, K., Chorozoglou, M., Becque, T., Roberts, A., Liddiard, L., Nollett, C., Hooper, J., Prude, M., Wood, W., Thomas, K. S., Thomas-Jones, E., Williams, H. C., & Little, P. (2018). Emollient bath additives for the treatment of childhood eczema (BATHE): multi-centre pragmatic parallel group randomised controlled trial of clinical and cost-effectiveness. BMJ, 361, 1-8. https://doi.org/10.1136/bmj.k1332

Objectives: To determine the clinical and cost-effectiveness of including emollient bath additives in the management of childhood eczema.
Trial design: Pragmatic randomised open-label superiority trial with two parallel groups.
Setting and recrui... Read More about Emollient bath additives for the treatment of childhood eczema (BATHE): multi-centre pragmatic parallel group randomised controlled trial of clinical and cost-effectiveness.

Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape (2018)
Journal Article
Kader, T., Hill, P., Rakha, E. A., Campbell, I. G., & Gorringe, K. L. (2018). Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape. Breast Cancer Research, 20, 1-11. https://doi.org/10.1186/s13058-018-0967-1

Background
Atypical ductal hyperplasia (ADH) is a common diagnosis in the mammographic era and a significant clinical problem with wide variation in diagnosis and treatment. After a diagnosis of ADH on biopsy a proportion are upgraded to carcinoma u... Read More about Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape.

Sociodemographic and medical risk factors associated with antepartum depression (2018)
Journal Article
Babu, G. R., Murthy, G. V. S., Singh, N., Nath, A., Rathnaiah, M., Saldanha, N., Deepa, R., & Kinra, S. (2018). Sociodemographic and medical risk factors associated with antepartum depression. Frontiers in Public Health, 6, Article 127. https://doi.org/10.3389/fpubh.2018.00127

Background: The increasing recognition of antenatal depression is an emerging area of concern in developing countres. We conducted a study to estimate the prevalence of antenatal mental distress and its relation with sociodemographic factors, obstetr... Read More about Sociodemographic and medical risk factors associated with antepartum depression.

Development of a multimedia educational programme for first-time hearing aid users: a participatory design (2018)
Journal Article
Ferguson, M. A., Leighton, P., Brandreth, M., & Wharrad, H. (in press). Development of a multimedia educational programme for first-time hearing aid users: a participatory design. International Journal of Audiology, https://doi.org/10.1080/14992027.2018.1457803

Objective: To develop content for a series of interactive video tutorials (or reusable learning objects, RLOs) for first-time adult hearing aid users, to enhance knowledge of hearing aids and communication.
Design: RLO content was based on an elect... Read More about Development of a multimedia educational programme for first-time hearing aid users: a participatory design.

Reasons for presenteeism in nurses working in geriatric settings: a qualitative study (2018)
Journal Article
Fiorini, L. A., Griffiths, A., & Houdmont, J. (in press). Reasons for presenteeism in nurses working in geriatric settings: a qualitative study. Journal of Hospital Administration, 7(4), https://doi.org/10.5430/jha.v7n4p9

Objective: To explore the perceived causes of presenteeism in nurses on geriatric wards.
Background: Presenteeism, defined as working when unwell, is associated with lost productivity and increased absenteeism. It is more commonly reported by employ... Read More about Reasons for presenteeism in nurses working in geriatric settings: a qualitative study.

Tumour heterogeneity of breast cancer: from morphology to personalised medicine (2018)
Journal Article
Aleskandarany, M. A., Vandenberghe, M. E., Marchiò, C., Ellis, I. O., Sapino, A., & Rakha, E. A. (2018). Tumour heterogeneity of breast cancer: from morphology to personalised medicine. Pathobiology, 85(1-2), 23-34. https://doi.org/10.1159/000477851

Breast cancer (BC) displays striking clinical, morphological, and behavioural diversity within a single tumour and between tumours. Currently, mounting evidence indicates that the morphological heterogeneity of BC reflects an underlying spectrum of g... Read More about Tumour heterogeneity of breast cancer: from morphology to personalised medicine.

Interventions for preventing occupational irritant hand dermatitis (Review) (2018)
Journal Article
Bauer, A., Rönsch, H., Elsner, P., Dittmar, D., Bennett, C., Schuttelaar, M.-L. A., Lukács, J., John, S. M., & Williams, H. C. (in press). Interventions for preventing occupational irritant hand dermatitis (Review). Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD004414.pub3

Background:
Occupational irritant hand dermatitis (OIHD) causes significant functional impairment, disruption of work, and discomfort in the working population. Different preventive measures such as protective gloves, barrier creams and moisturisers... Read More about Interventions for preventing occupational irritant hand dermatitis (Review).

A gyral coordinate system predictive of fibre orientations (2018)
Journal Article
Cottaar, M., Bastiani, M., Chen, C., Dikranian, K., Van Essen, D., Behrens, T. E., Sotiropoulos, S. N., & Jbabdi, S. (2018). A gyral coordinate system predictive of fibre orientations. NeuroImage, 176, https://doi.org/10.1016/j.neuroimage.2018.04.040

When axonal fibres approach or leave the cortex, their trajectories tend to closely follow the cortical convolutions. To quantify this tendency, we propose a three-dimensional coordinate system based on the gyral geometry. For every voxel in the brai... Read More about A gyral coordinate system predictive of fibre orientations.

Feasibility of personalised remote long-term follow-up of people with cochlear implants: a randomised controlled trial (2018)
Journal Article
Cullington, H., Kitterick, P. T., Weal, M., & Margol-Gromada, M. (2018). Feasibility of personalised remote long-term follow-up of people with cochlear implants: a randomised controlled trial. BMJ Open, 8(4), Article e019640. https://doi.org/10.1136/bmjopen-2017-019640

Introduction: substantial resources are required to provide lifelong post-operative care to people with cochlear implants. Most patients visit the clinic annually. We introduced a person-centred remote follow-up pathway, giving patients telemedicine... Read More about Feasibility of personalised remote long-term follow-up of people with cochlear implants: a randomised controlled trial.

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative) (2018)
Journal Article
Chalmers, J., Thomas, K., Apfelbacher, C., Williams, H., Prinsen, C., Spuls, P., Simpson, E., Gerbens, L., Boers, M., Barbarot, S., Stalder, J., Abuabara, K., Aoki, V., Ardeleanu, M., Armstrong, J., Bang, B., Berents, T., Burton, T., Butler, L., Chubachi, T., …Zaniboni, M. (2018). Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative). British Journal of Dermatology, 178(5), e332-e341. https://doi.org/10.1111/bjd.16543

This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus... Read More about Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).