Outputs (23)

Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake (2009)
Journal Article
Gardiner, J. V., Bataveljic, A., Patel, N. A., Bewick, G. A., Roy, D., Campbell, D., Greenwood, H. C., Murphy, K. G., Hameed, S., Jethwa, P. H., Ebling, F. J., Vickers, S. P., Cheetham, S., Ghatei, M. A., Bloom, S. R., & Dhillo, W. S. (2010). Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake. Diabetes, 59(2), 397-406. https://doi.org/10.2337/db09-1198

OBJECTIVE-Prokineticin 2 (PK2) is a hypothalamic neuropeptide expressed in central nervous system areas known to be involved in food intake. We therefore hypothesized that PK2 plays a role in energy homeostasis. RESEARCH DESIGN AND METHODS - We inves... Read More about Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake.

Dynamic distribution and stem cell characteristics of Sox1-expressing cells in the cerebellar cortex (2009)
Journal Article
Alcock, J., & Sottile, V. (2009). Dynamic distribution and stem cell characteristics of Sox1-expressing cells in the cerebellar cortex. Cell Research, 19(12), 1324-1333. https://doi.org/10.1038/cr.2009.119

Bergmann glia cells are a discrete radial glia population surrounding Purkinje cells in the cerebellar cortex. Although Bergmann glia are essential for the development and correct arborization of Purkinje cells, little is known about the regulation o... Read More about Dynamic distribution and stem cell characteristics of Sox1-expressing cells in the cerebellar cortex.

Heligmosomoides bakeri: a model for exploring the biology and genetics of resistance to chronic gastrointestinal nematode infections (2009)
Journal Article
Behnke, J. M., Menge, D., & Noyes, H. (2009). Heligmosomoides bakeri: a model for exploring the biology and genetics of resistance to chronic gastrointestinal nematode infections. Parasitology, 136(12), https://doi.org/10.1017/S0031182009006003

The intestinal nematode Heligmosomoides bakeri has undergone 2 name changes during the last 4 decades. Originally, the name conferred on the organism in the early 20th century was Nematospiroides dubius, but this was dropped in favour of Heligmosomoi... Read More about Heligmosomoides bakeri: a model for exploring the biology and genetics of resistance to chronic gastrointestinal nematode infections.

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly (2009)
Journal Article
Lapaquette, P., Glasser, A. L., Huett, A., Xavier, R. J., & Darfeuille-Michaud, A. (2009). Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cellular Microbiology, 12(1), 99-113. https://doi.org/10.1111/j.1462-5822.2009.01381.x

Ileal lesions in Crohn's disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within intestinal epithelial cells. Recent genome-wide association studies have highlighted the autop... Read More about Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.

Early life programming of fear conditioning and extinction in adult male rats (2009)
Journal Article
Stevenson, C. W., Spicer, C. H., Mason, R., & Marsden, C. A. (2009). Early life programming of fear conditioning and extinction in adult male rats. Behavioural Brain Research, 205(2), 505-510. https://doi.org/10.1016/j.bbr.2009.08.005

The early rearing environment programs corticolimbic function and neuroendocrine stress reactivity in adulthood. Although early environmental programming of innate fear has been previously examined, its impact on fear learning and memory later in lif... Read More about Early life programming of fear conditioning and extinction in adult male rats.

The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptor (2009)
Journal Article
Lane, J. R., Beukers, M. W., Mulder-Krieger, T., & IJzerman, A. P. (2010). The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptor. Biochemical Pharmacology, 79(1), 48-56. https://doi.org/10.1016/j.bcp.2009.07.024

Studies of endogenous cannabinoid agonists, such as 2-arachidonylglycerol (2-AG), have revealed their potential to exert modulatory actions on other receptor systems in addition to their ability to activate cannabinoid receptors. This study investiga... Read More about The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptor.

Surviving mass extinction by bridging the benthic/planktic divide (2009)
Journal Article
Darling, K. F., Thomas, E., Kasemann, S. A., Seears, H. A., Smart, C. W., & Wade, C. M. (2009). Surviving mass extinction by bridging the benthic/planktic divide. Proceedings of the National Academy of Sciences, 106(31), 12629-12633. https://doi.org/10.1073/pnas.0902827106

Evolution of planktic organisms from benthic ancestors is commonly thought to represent unidirectional expansion into new ecological domains, possibly only once per clade. For foraminifera, this evolutionary expansion occurred in the Early-Middle Jur... Read More about Surviving mass extinction by bridging the benthic/planktic divide.

Autophagy at the gut interface: Mucosal responses to stress and the consequences for inflammatory bowel diseases (2009)
Journal Article
Huett, A., & Xavier, R. J. (2010). Autophagy at the gut interface: Mucosal responses to stress and the consequences for inflammatory bowel diseases. Inflammatory Bowel Diseases, 16(1), 152-174. https://doi.org/10.1002/ibd.20991

Autophagy is a conserved homeostatic process by which cells degrade and recycle cytoplasmic contents and organelles. Recently, autophagy has come to prominence as a factor in many disease states, including inflammatory bowel diseases. In this review... Read More about Autophagy at the gut interface: Mucosal responses to stress and the consequences for inflammatory bowel diseases.

Helminth species richness in wild wood mice, Apodemus sylvaticus, is enhanced by the presence of the intestinal nematode Heligmosomoides polygyrus (2009)
Journal Article
Behnke, J., Eira, C., Rogan, M., Gilbert, F., Torres, J., Miquel, J., & Lewis, J. (2009). Helminth species richness in wild wood mice, Apodemus sylvaticus, is enhanced by the presence of the intestinal nematode Heligmosomoides polygyrus. Parasitology, 136(7), https://doi.org/10.1017/S0031182009006039

We analysed 3 independently collected datasets of fully censused helminth burdens in wood mice, Apodemus sylvaticus, testing the a priori hypothesis of Behnke et al. (2005) that the presence of the intestinal nematode Heligmosomoides polygyrus predis... Read More about Helminth species richness in wild wood mice, Apodemus sylvaticus, is enhanced by the presence of the intestinal nematode Heligmosomoides polygyrus.

AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge (2009)
Journal Article
Oldfield, N. J., Worrall, K. E., Rycroft, A. N., Ali, T., Wooldridge, K. G., & Ala'Aldeen, D. A. (2009). AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge. Vaccine, 27(38), 5278-5283. https://doi.org/10.1016/j.vaccine.2009.06.047

Actinobacillus pleuropneumoniae is a major respiratory pathogen of pigs; current vaccines provide only limited protection. AasP, a subtilisin-like serine protease, is a conserved outer membrane-localised autotransporter protein. We hypothesized that... Read More about AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge.