Outputs (111)

Avian Cardiovascular Disease Characteristics, Causes and Genomics (2018)
Book Chapter
Kubale, V., Merry, K., Miller, G., Ruiz Diaz, M., & Rutland, C. (2018). Avian Cardiovascular Disease Characteristics, Causes and Genomics. In X. Liu (Ed.), Application of genetics and genomics in poultry science (141-162). InTech. https://doi.org/10.5772/intechopen.78005

Cardiovascular disease is common in avian species and increasing commercial economic losses and demand for healthcare in the household/smallholding veterinary sector has resulted in increased research into these disorders. This in turn has highlighte... Read More about Avian Cardiovascular Disease Characteristics, Causes and Genomics.

Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: a novel treatment of naturally occurring tendinitis and desmitis in horses (2018)
Journal Article
Kovac, M., Litvin, Y. A., Aliev, R. O., Zakirova, E. Y., Rutland, C. S., Kiyasov, A. P., & Rizvanov, A. A. (2018). Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: a novel treatment of naturally occurring tendinitis and desmitis in horses. Frontiers in Pharmacology, 9, https://doi.org/10.3389/fphar.2018.00978

This clinical study describes the intralesional application of the plasmid DNA encoding two therapeutic species-specific growth factors: vascular endothelial growth factor (VEGF164) and fibroblast growth factor 2 (FGF2) in seven horses to restore nat... Read More about Gene therapy using plasmid DNA encoding VEGF164 and FGF2 genes: a novel treatment of naturally occurring tendinitis and desmitis in horses.

Prevalence of antibodies against Toxoplasma gondii in pets and their owners in Shandong province, Eastern China (2018)
Journal Article
Cong, W., Elsheikha, H. M., Zhou, N., Peng, P., Qin, S.-Y., Meng, Q.-F., & Qian, A.-D. (2018). Prevalence of antibodies against Toxoplasma gondii in pets and their owners in Shandong province, Eastern China. BMC Infectious Diseases, 18(1), Article 430. https://doi.org/10.1186/s12879-018-3307-2

Background: Pet ownership in China has been steadily increasing over recent years. However, the risk of pet-associated zoonotic infection with the protozoan parasite Toxoplasma gondii remains poorly defined.
Methods: In a cross-sectional survey, we... Read More about Prevalence of antibodies against Toxoplasma gondii in pets and their owners in Shandong province, Eastern China.

Functional characterization of dense granule proteins in Toxoplasma gondii RH strain using CRISPR-Cas9 system (2018)
Journal Article
Bai, M.-J., Wang, J.-L., Elsheikha, H. M., Liang, Q.-L., Chen, K., Nie, L.-B., & Zhu, X.-Q. (2018). Functional characterization of dense granule proteins in Toxoplasma gondii RH strain using CRISPR-Cas9 system. Frontiers in Cellular and Infection Microbiology, 8, 1-9. https://doi.org/10.3389/fcimb.2018.00300

Infection with the apicomplexan protozoan parasite Toxoplasma gondii is an ongoing public health problem. The parasite's ability to invade and replicate within the host cell is dependent on many effectors, such as dense granule proteins (GRAs) releas... Read More about Functional characterization of dense granule proteins in Toxoplasma gondii RH strain using CRISPR-Cas9 system.

CARM1 (PRMT4) acts as a transcriptional coactivator during retinoic acid-induced embryonic stem cell differentiation (2018)
Journal Article
Quintero, C. M., Laursen, K. B., Mongan, N. P., Luo, M., & Gudas, L. J. (2018). CARM1 (PRMT4) acts as a transcriptional coactivator during retinoic acid-induced embryonic stem cell differentiation. Journal of Molecular Biology, 430(21), 4168-4182. https://doi.org/10.1016/j.jmb.2018.08.014

Activation of the retinoic acid (RA) signaling pathway is important for controlling embryonic stem cell differentiation and development. Modulation of this pathway occurs through the recruitment of different epigenetic regulators at the retinoic acid... Read More about CARM1 (PRMT4) acts as a transcriptional coactivator during retinoic acid-induced embryonic stem cell differentiation.

A clinical study to evaluate the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and to evaluate their suitability for the immobilisation of healthy chimpanzees (2018)
Journal Article
Strong, V., Möller, T., Tillman, A.-S., Träff, S., Guevara, L., Martin, M., Redrobe, S., & White, K. (2018). A clinical study to evaluate the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and to evaluate their suitability for the immobilisation of healthy chimpanzees. Veterinary Anaesthesia and Analgesia, https://doi.org/10.1016/j.vaa.2018.06.015

Objective: To characterise the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and their suitability for the immobilisation of healthy chimpanzees undergoing cardiac assessment.
Study de... Read More about A clinical study to evaluate the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and to evaluate their suitability for the immobilisation of healthy chimpanzees.

The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor (2018)
Journal Article
Sarwar, M., Syed Khaja, A. S., Aleskandarany, M., Karlsson, R., Althobiti, M., Ødum, N., Mongan, N. P., Dizeyi, N., Johnson, H., Green, A. R., Ellis, I. O., Rakha, E. A., & Persson, J. L. (2019). The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor. Oncogene, 38(3), 375-389. https://doi.org/10.1038/s41388-018-0438-2

© 2018, The Author(s). Despite recent improvement in adjuvant therapies, triple-negative, and ER + subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinosi... Read More about The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor.

Bird-biting mosquitoes on farms in southern England (2018)
Journal Article
Brugman, V. A., Medlock, J. M., Logan, J. G., Wilson, A. J., Lindsay, S. W., Fooks, A. R., Mertens, P. P., Johnson, N., & Carpenter, S. T. (2018). Bird-biting mosquitoes on farms in southern England. Veterinary Record, vetrec-2017-104830. https://doi.org/10.1136/vr.104830

Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness (2018)
Journal Article
Harvey, N., Daly, C., Clark, N., Ransford, E., Wallace, S., & Yon, L. (2018). Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness. Animals, 8(8), Article 132. https://doi.org/10.3390/ani8080132

Opportunities for positive social interaction are important in captive animals, and social interactions can be used as a welfare indicator. Wild elephants live in related multigenerational herds; however, in captivity they are often managed in less r... Read More about Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness.

Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis (2018)
Journal Article
Andrade Gomes, S., Lowrie, M., & Targett, M. (2018). Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis. Veterinary Record, https://doi.org/10.1136/vr.104741

Lateral foraminotomy has been described as an effective surgical treatment for foraminal stenosis in the treatment of degenerative lumbosacral stenosis (DLSS) in dogs. Clinical records were reviewed from 45 dogs which had undergone lateral foraminoto... Read More about Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis.