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Outputs (119)

A Fibromyxoid Stromal Response is Associated with Muscle Invasion in Canine Urothelial Carcinoma (2019)
Journal Article
de Brot, S., Grau-Roma, L., Stirling-Stainsby, C., Dettwiler, M., Guscetti, F., Meier, D., …Mongan, N. (2019). A Fibromyxoid Stromal Response is Associated with Muscle Invasion in Canine Urothelial Carcinoma. Journal of Comparative Pathology, 169, 35-46. https://doi.org/10.1016/j.jcpa.2019.04.003

Canine urothelial carcinoma (UC) is the most common type of cancer of the lower urinary tract and tends to affect elderly neutered female dogs, with a high predisposition for Scottish terriers. Tumour stroma, inflammation and necrosis are poorly char... Read More about A Fibromyxoid Stromal Response is Associated with Muscle Invasion in Canine Urothelial Carcinoma.

Plasma and urine pharmacokinetics of intravenously administered flunixin in greyhound dogs (2019)
Journal Article
Morris, T., Paine, S. W., Zahra, P., Li, E., Colgan, S., & Karamatic, S. (2019). Plasma and urine pharmacokinetics of intravenously administered flunixin in greyhound dogs. Journal of Veterinary Pharmacology and Therapeutics, 42(5), 505-510. https://doi.org/10.1111/jvp.12775

© 2019 John Wiley & Sons Ltd Medication control in greyhound racing requires information from administration studies that measure drug levels in the urine as well as plasma, with time points that extend into the terminal phase of excretion. To char... Read More about Plasma and urine pharmacokinetics of intravenously administered flunixin in greyhound dogs.

Is there an evidence base for veterinarians to utilise when treating commonly seen conditions in cattle? (2019)
Journal Article
Bradford, N., Huntley, S., Grindlay, D., & Brennan, M. (2019). Is there an evidence base for veterinarians to utilise when treating commonly seen conditions in cattle?. Cattle Practice, 27(1), 12-25

Evidence based veterinary medicine (EVM) is an integral part of clinical decision-making in practice. In order for EVM to be utilised effectively, relevant published evidence must be available to veterinarians. Currently there is a lack of research i... Read More about Is there an evidence base for veterinarians to utilise when treating commonly seen conditions in cattle?.

Metadherin: A Therapeutic Target in Multiple Cancers (2019)
Journal Article
Dhiman, G., Srivastava, N., Goyal, M., Rakha, E., Lothion-Roy, J., Mongan, N. P., …Baranwal, M. (2019). Metadherin: A Therapeutic Target in Multiple Cancers. Frontiers in Oncology, 9, Article 349. https://doi.org/10.3389/fonc.2019.00349

Altered expression of many genes and proteins is essential for cancer development and progression. Recently, the affected expression of metadherin (MTDH), also known as AEG-1 (Astrocyte Elevated Gene 1) and Lyric, has been implicated in various aspec... Read More about Metadherin: A Therapeutic Target in Multiple Cancers.

Increasing vet and sheep flock interactions in dairy practice (2019)
Journal Article
Gasgoine, E., Lovatt, F., Davies, A., & Reader, J. (2019). Increasing vet and sheep flock interactions in dairy practice. In Practice, 41(4), 177-181. https://doi.org/10.1136/inp.l1530

© 2019 BMJ Publishing Group Limited. Sheep medicine has traditionally been a low priority for cattle-dominated practice, as it is commonly thought that there is minimal financial opportunities in this sector. The perception has been that the vet's ro... Read More about Increasing vet and sheep flock interactions in dairy practice.

First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats ( Rattus norvegicus ) from Great Britain (2019)
Journal Article
Murphy, E. G., Williams, N. J., Jennings, D., Chantrey, J., Verin, R., Grierson, S., …Bennett, M. (2019). First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats ( Rattus norvegicus ) from Great Britain. Zoonoses and Public Health, 66(6), 686-694. https://doi.org/10.1111/zph.12581

In the United Kingdom, there has been an increase in the number of hepatitis E virus (HEV) infections in people annually since 2010. Most of these are thought to be indigenously acquired Orthohepevirus A genotype 3 (HEV G3), which has been linked to... Read More about First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats ( Rattus norvegicus ) from Great Britain.

New insights into the mechanical properties of Acanthamoeba castellanii cysts as revealed by phonon microscopy (2019)
Journal Article
Pérez-Cota, F., Smith, R. J., Elsheikha, H. M., & Clark, M. (2019). New insights into the mechanical properties of Acanthamoeba castellanii cysts as revealed by phonon microscopy. Biomedical Optics Express, 10(5), 2399-2408. https://doi.org/10.1364/BOE.10.002399

The single cell eukaryotic protozoan Acanthamoeba castellanii exhibits a remarkable ability to switch from a vegetative trophozoite stage to a cystic form, in response to stressors. This phenotypic switch involves changes in gene expression and synth... Read More about New insights into the mechanical properties of Acanthamoeba castellanii cysts as revealed by phonon microscopy.

Low protein intake during the preconception period in beef heifers affects offspring and maternal behaviour (2019)
Journal Article
Miguel-Pacheco, G. G., Perry, V. E., Hernandez-Medrano, J. H., Wapenaar, W., Keisler, D. H., & Voigt, J. P. (2019). Low protein intake during the preconception period in beef heifers affects offspring and maternal behaviour. Applied Animal Behaviour Science, 215, 1-6. https://doi.org/10.1016/j.applanim.2019.04.003

Maternal low protein diets prior to conception alter embryo and fetal development and are associated with detrimental outcomes in the offspring in many species. The aim of this study in beef cattle was to investigate the effect of preconception dieta... Read More about Low protein intake during the preconception period in beef heifers affects offspring and maternal behaviour.

A case of identity: HOX genes in normal and cancer stem cells (2019)
Journal Article
Smith, J., Zyoud, A., & Allegrucci, C. (2019). A case of identity: HOX genes in normal and cancer stem cells. Cancers, 11(4), 1-13. https://doi.org/10.3390/cancers11040512

Stem cells are undifferentiated cells that have the unique ability to self-renew and differentiate into many different cell types. Their function is controlled by core gene networks whose misregulation can result in aberrant stem cell function and de... Read More about A case of identity: HOX genes in normal and cancer stem cells.