Outputs (32)

Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D. O., Boto, E., Holmes, N., Hill, R. M., …Brookes, M. J. (2024). Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography. eLife, 13, Article RP94561. https://doi.org/10.7554/elife.94561.3

Neural oscillations mediate the coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only an important neuroscientific question but could also shed lig... Read More about Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography.

Swallow Tail Sign: Revisited (2022)
Journal Article
Brammerloh, M., Kirilina, E., Alkemade, A., Bazin, P.-L., Jantzen, C., Jäger, C., …Weiskopf, N. (2022). Swallow Tail Sign: Revisited. Radiology, 305(3), 674-677. https://doi.org/10.1148/radiol.212696

The loss of the radiologic swallow tail sign on MRI scans of the substantia nigra is a promising diagnostic marker of Parkinson disease (1), although its anatom-ic underpinning is unclear. An early influential study showed th... Read More about Swallow Tail Sign: Revisited.

Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging (2022)
Journal Article
Wang, C., Martins-Bach, A. B., Alfaro-Almagro, F., Douaud, G., Klein, J. C., Llera, A., Fiscone, C., Bowtell, R., Elliott, L. T., Smith, S. M., Tendler, B. C., & Miller, K. L. (2022). Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging. Nature Neuroscience, 25(6), 818-831. https://doi.org/10.1038/s41593-022-01074-w

A key aim in epidemiological neuroscience is identification of markers to assess brain health and monitor therapeutic interventions. Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging technique that measures tissue ma... Read More about Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging.

Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning (2022)
Journal Article
Owens, M. M., Albaugh, M. D., Allgaier, N., Yuan, D., Robert, G., Cupertino, R. B., …Hohmann, S. (2022). Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning. Translational Psychiatry, 12(1), Article 188. https://doi.org/10.1038/s41398-022-01956-4

While there is substantial evidence that cannabis use is associated with differences in human brain development, most of this evidence is correlational in nature. Bayesian causal network (BCN) modeling attempts to identify probable causal relationshi... Read More about Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning.

Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial) (2022)
Journal Article
Carneiro, L., White, J., Parker, H., Hoad, C., Tucker, E., Marciani, L., …Fox, M. (2022). Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial). Nutrients, 14(7), Article 1321. https://doi.org/10.3390/nu14071321

Nausea, vomiting and abdominal pain in diabetic patients are often attributed to diabetic gastropathy (DG). Post-pyloric (“jejunal”) enteral nutrition (JN) may improve nutrition and glycaemia in difficult cases. The acute effects of JN on postprandia... Read More about Pilot Double-Blind Randomised Controlled Trial: Effects of Jejunal Nutrition on Postprandial Distress in Diabetic Gastropathy (J4G Trial).

Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents (2021)
Journal Article
Ottino-González, J., Albaugh, M. D., Cao, Z., Cupertino, R. B., Schwab, N., Spechler, P. A., …Garavan, H. (2022). Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents. Addiction, 117(5), 1312-1325. https://doi.org/10.1111/add.15772

BACKGROUND AND AIMS: Graph theoretic analysis of structural covariance networks (SCN) provides an assessment of brain organization that has not yet been applied to alcohol dependence (AD). We estimated whether SCN differences are present in adults wi... Read More about Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents.

The Human Connectome Project: A retrospective (2021)
Journal Article
Elam, J. S., Glasser, M. F., Harms, M. P., Sotiropoulos, S. N., Andersson, J. L., Burgess, G. C., …Van Essen, D. C. (2021). The Human Connectome Project: A retrospective. NeuroImage, 244, Article 118543. https://doi.org/10.1016/j.neuroimage.2021.118543

The Human Connectome Project (HCP) was launched in 2010 as an ambitious effort to accelerate advances in human neuroimaging, particularly for measures of brain connectivity; apply these advances to study a large number of healthy young adults; and fr... Read More about The Human Connectome Project: A retrospective.

Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data (2021)
Journal Article
Toenders, Y. J., Kottaram, A., Dinga, R., Davey, C. G., Banaschewski, T., Bokde, A. L., …Schmaal, L. (2022). Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7(4), 376-384. https://doi.org/10.1016/j.bpsc.2021.03.005

Background
Adolescent onset of depression is associated with long-lasting negative consequences. Identifying adolescents at risk for developing depression would enable the monitoring of risk-factors and the development of early intervention strategi... Read More about Predicting Depression Onset in Young People Based on Clinical, Cognitive, Environmental, and Neurobiological Data.

XTRACT - Standardised protocols for automated tractography in the human and macaque brain (2020)
Journal Article
Warrington, S., Bryant, K. L., Khrapitchev, A. A., Sallet, J., Charquero-Ballester, M., Douaud, G., …Sotiropoulos, S. N. (2020). XTRACT - Standardised protocols for automated tractography in the human and macaque brain. NeuroImage, 217, Article 116923. https://doi.org/10.1016/j.neuroimage.2020.116923

We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (... Read More about XTRACT - Standardised protocols for automated tractography in the human and macaque brain.

Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy (2019)
Journal Article
Voets, N. L., Alvarez, I., Qiu, D., Leatherday, C., Willie, J. T., Sotiropoulos, S., …Drane, D. L. (2019). Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy. Stereotactic and Functional Neurosurgery, 97(4), 255–265. https://doi.org/10.1159/000502701

Selective laser amygdalohippocampotomy (SLAH) is a minimally invasive surgical treatment for medial temporal lobe epilepsy. Visual field deficits (VFDs) are a significant potential complication. The objective of this study was to determine the relati... Read More about Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy.

MRI of the colon in the pharmaceutical field: the future before us (2019)
Journal Article
Sulaiman, S., & Marciani, L. (2019). MRI of the colon in the pharmaceutical field: the future before us. Pharmaceutics, 11(4), Article 146. https://doi.org/10.3390/pharmaceutics11040146

Oral solid drug formulation is the most common route for administration and it is vital to increase knowledge of the gastrointestinal physiological environment to understand dissolution and absorption processes and to develop reliable biorelevant in... Read More about MRI of the colon in the pharmaceutical field: the future before us.

Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics (2019)
Journal Article
Demirtas, M., Burt, J. B., Helmer, M., Ji, J. L., Adkinson, B. D., Glasser, M. F., …Murray, J. D. (2019). Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics. Neuron, 101(6), 1181-1194.e13. https://doi.org/10.1016/j.neuron.2019.01.017

The large-scale organization of dynamical neural activity across cortex emerges through long-range interactions among local circuits. We hypothesized that large-scale dynamics are also shaped by heterogeneity of intrinsic local properties across cort... Read More about Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics.

Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes (2018)
Journal Article
Hernandez-Fernandez, M., Reguly, I., Jbabdi, S., Giles, M., Smith, S., & Sotiropoulos, S. N. (2019). Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes. NeuroImage, 188, 598-615. https://doi.org/10.1016/j.neuroimage.2018.12.015

The great potential of computational diffusion MRI (dMRI) relies on indirect inference of tissue microstructure and brain connections, since modelling and tractography frameworks map diffusion measurements to neuroanatomical features. This mapping ho... Read More about Using GPUs to accelerate computational diffusion MRI: from microstructure estimation to tractography and connectomes.

Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold (2018)
Journal Article
Hoad, C., Marciani, L., Spiller, R., Gowland, P., & Moran, G. (2019). Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold. Neurogastroenterology and Motility, 31(1), e13466. https://doi.org/10.1111/nmo.13466

Background

The symptoms of functional bowel disorders are common in postprandial but investigations are generally undertaken in the fasted state using invasive procedures. MRI provides a noninvasive tool to study the gastrointestinal tract in an u... Read More about Cine MRI assessment of motility in the unprepared small bowel in the fasting and fed state: beyond the breath-hold.

Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function (2018)
Journal Article
Tierney, T. M., Holmes, N., Meyer, S. S., Boto, E., Roberts, G., Leggett, J., …Barnes, G. R. (2018). Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function. NeuroImage, 181, 513-520. https://doi.org/10.1016/j.neuroimage.2018.07.035

Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically valida... Read More about Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function.

A bi-planar coil system for nulling background magnetic fields in scalp mounted magnetoencephalography (2018)
Journal Article
Holmes, N., Leggett, J., Boto, E., Roberts, G., Hill, R. M., Tierney, T. M., …Bowtell, R. (2018). A bi-planar coil system for nulling background magnetic fields in scalp mounted magnetoencephalography. NeuroImage, 181, 760-774. https://doi.org/10.1016/j.neuroimage.2018.07.028

Small, commercially-available Optically Pumped Magnetometers (OPMs) can be used to construct a wearable Magnetoencephalography (MEG) system that allows large head movements to be made during recording. The small dynamic range of these sensors however... Read More about A bi-planar coil system for nulling background magnetic fields in scalp mounted magnetoencephalography.

Cognition based bTBI mechanistic criteria; a tool for preventive and therapeutic innovations (2018)
Journal Article
Garcia-Gonzalez, D., Race, N. S., Voets, N. L., Jenkins, D. R., Sotiropoulos, S. N., Acosta, G., Cruz-Haces, M., Tang, J., Shi, R., & Jérusalem, A. (in press). Cognition based bTBI mechanistic criteria; a tool for preventive and therapeutic innovations. Scientific Reports, 8, Article 10273. https://doi.org/10.1038/s41598-018-28271-7

Blast-induced traumatic brain injury has been associated with neurodegenerative and neuropsychiatric disorders. To date, although damage due to oxidative stress appears to be important, the specific mechanistic causes of such disorders remain elusive... Read More about Cognition based bTBI mechanistic criteria; a tool for preventive and therapeutic innovations.

Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project (2018)
Journal Article
Bastiani, M., Andersson, J. L., Cordero-Grande, L., Murgasova, M., Hutter, J., Price, A. N., Makropoulos, A., Fitzgibbon, S. P., Hughes, E. J., Rueckert, D., Suresh, V., Rutherford, M., Edwards, A. D., Smith, S., Tournier, J. D., Hajnal, J. V., Jbabdi, S., & Sotiropoulos, S. N. (2019). Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project. NeuroImage, 185, 750-763. https://doi.org/10.1016/j.neuroimage.2018.05.064

The developing Human Connectome Project is set to create and make available to the scientific community a 4-dimensional map of functional and structural cerebral connectivity from 20 to 44 weeks post-menstrual age, to allow exploration of the genetic... Read More about Automated processing pipeline for neonatal diffusion MRI in the developing Human Connectome Project.

Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI (2018)
Journal Article
Schwarz, S. T., Mougin, O., Xing, Y., Blazejewska, A., Bajaj, N., Auer, D. P., & Gowland, P. (2018). Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI. NeuroImage: Clinical, 19, 683-689. https://doi.org/10.1016/j.nicl.2018.05.027

Improved markers for the progression of Parkinson's disease (PD) are required. Previous work has proven that iron dependent MRI scans can detect the largest Nigrosome (N1) within the substantia nigra (SN) pars compacta and changes in PD. Histopatholo... Read More about Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI.

Whole brain comparative anatomy using connectivity blueprints (2018)
Journal Article
Mars, R. B., Sotiropoulos, S. N., Passingham, R. E., Sallet, J., Verhagen, L., Khrapitchev, A. A., Sibson, N., & Jbabdi, S. (in press). Whole brain comparative anatomy using connectivity blueprints. eLife, 7, Article e35237. https://doi.org/10.7554/eLife.35237

Comparing the brains of related species faces the challenges of establishing homologies whilst accommodating evolutionary specializations. Here we propose a general framework for understanding similarities and differences between the brains of primat... Read More about Whole brain comparative anatomy using connectivity blueprints.