Konstantinos I. Papadimitriou
A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules
Papadimitriou, Konstantinos I.; Dempsey, Laura A.; Hebden, Jeremy C.; Arridge, Simon R.; Powell, Samuel
Authors
Laura A. Dempsey
Jeremy C. Hebden
Simon R. Arridge
Samuel Powell
Abstract
We introduce a compact time-domain system for near-infrared spectroscopy using a spread spectrum technique. The proof-of-concept single channel instrument utilises a low-cost commercially available optical transceiver module as a light source, controlled by a Kintex 7 field programmable gate array (FPGA). The FPGA modulates the optical transceiver with maximum-length sequences at line rates up to 10Gb/s, allowing us to achieve an instrument response function with full width at half maximum under 600ps. The instrument is characterised through a set of detailed phantom measurements as well as proof-of-concept in vivo measurements, demonstrating performance comparable with conventional pulsed time-domain near-infrared spectroscopy systems.
Citation
Papadimitriou, K. I., Dempsey, L. A., Hebden, J. C., Arridge, S. R., & Powell, S. (2018). A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules. Biomedical Optics Express, 9(6), 2648 - 2663. https://doi.org/10.1364/boe.9.002648
Journal Article Type | Article |
---|---|
Acceptance Date | Apr 1, 2018 |
Online Publication Date | May 10, 2018 |
Publication Date | Jun 1, 2018 |
Deposit Date | Jan 24, 2020 |
Publicly Available Date | Jan 24, 2020 |
Journal | Biomedical Optics Express |
Electronic ISSN | 2156-7085 |
Publisher | Optical Society of America |
Peer Reviewed | Peer Reviewed |
Volume | 9 |
Issue | 6 |
Pages | 2648 - 2663 |
DOI | https://doi.org/10.1364/boe.9.002648 |
Keywords | Biotechnology; Atomic and Molecular Physics, and Optics |
Public URL | https://nottingham-repository.worktribe.com/output/3791666 |
Publisher URL | https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-6-2648 |
Additional Information | This article is maintained by: OSA - The Optical Society; Crossref DOI link to publisher maintained version: https://doi.org/10.1364/BOE.9.002648; Article type: research-article; Similarity check: Screened by Similarity Check; Peer reviewed: Yes; Review process: Single blind; Received: 20 February 2018; Accepted: 24 April 2018; Published: 10 May 2018; Copyright: Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. |
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