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Dr MATTEA FINELLI's Outputs (23)

Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration (2011)
Journal Article
Oliver, P. L., Finelli, M. J., Edwards, B., Bitoun, E., Butts, D. L., Becker, E. B. E., Cheeseman, M. T., Davies, B., & Davies, K. E. (2011). Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration. PLoS Genetics, 7(10), Article e1002338. https://doi.org/10.1371/journal.pgen.1002338

Oxidative stress is a common etiological feature of neurological disorders, although the pathways that govern defence against reactive oxygen species (ROS) in neurodegeneration remain unclear. We have identified the role of oxidation resistance 1 (Ox... Read More about Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration.

AF4 Is a Critical Regulator of the IGF-1 Signaling Pathway during Purkinje Cell Development (2009)
Journal Article
Bitoun, E., Finelli, M. J., Oliver, P. L., Lee, S., & Davies, K. E. (2009). AF4 Is a Critical Regulator of the IGF-1 Signaling Pathway during Purkinje Cell Development. Journal of Neuroscience, 29(49), 15366-15374. https://doi.org/10.1523/jneurosci.5188-09.2009

Deregulation of the insulin-like growth factor 1 (IGF-1) signaling pathway is a recurrent finding in mouse models and human patients with cerebellar ataxia and thus represents a common pathological cascade in neuronal cell death that may be targeted... Read More about AF4 Is a Critical Regulator of the IGF-1 Signaling Pathway during Purkinje Cell Development.