Skip to main content

Research Repository

Advanced Search

Dr Katherine Dyke's Outputs (17)

Investigating Neurometabolite Changes in Response to Median Nerve Stimulation (2025)
Journal Article
Houlgreave, M. S., Dyke, K., Berrington, A., & Jackson, S. R. (2025). Investigating Neurometabolite Changes in Response to Median Nerve Stimulation. Brain and Behavior, 15(1), Article e70250. https://doi.org/10.1002/brb3.70250

Background: Rhythmic median nerve stimulation (MNS) at 10Hz has been shown to cause a substantial reduction in tic frequency in individuals with Tourette syndrome. The mechanism of action is currently unknown but is hypothesized to involve entrainmen... Read More about Investigating Neurometabolite Changes in Response to Median Nerve Stimulation.

A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder (2023)
Journal Article
Morera Maiquez, B., Morera Maiquez, B., Smith, C., Dyke, K., Chou, C.-P., Kasbia, B., McCready, C., Wright, H., Jackson, J. K., Farr, I., Badinger, E., Jackson, G. M., & Jackson, S. R. (2023). A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder. Journal of Neuropsychology, 17(3), 540-563. https://doi.org/10.1111/jnp.12313

Tourette syndrome (TS) and chronic tic disorder (CTD) are neurological disorders of childhood onset characterized by the occurrence of tics; repetitive, purposeless, movements or vocalizations of short duration which can occur many times throughout a... Read More about A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder.

Non-invasive brain stimulation as therapy: systematic review and recommendations with a focus on the treatment of Tourette syndrome (2021)
Journal Article
Dyke, K., Jackson, G., & Jackson, S. (2022). Non-invasive brain stimulation as therapy: systematic review and recommendations with a focus on the treatment of Tourette syndrome. Experimental Brain Research, 240(2), 341-363. https://doi.org/10.1007/s00221-021-06229-y

Tourette syndrome (TS) is a neurodevelopmental condition characterised by tics, which are stereotyped movements and/or vocalisations. Tics often cause difficulties in daily life and many with TS express a desire to reduce and/or gain control over the... Read More about Non-invasive brain stimulation as therapy: systematic review and recommendations with a focus on the treatment of Tourette syndrome.

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2021)
Journal Article
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. (2021). The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome. Journal of Neuropsychology, 15(3), 340-362. https://doi.org/10.1111/jnp.12242

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterized by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Acute gabapentin administration in healthy adults. A double-blind placebo-controlled study using transcranial magnetic stimulation and 7T 1H-MRS (2021)
Journal Article
Dyke, K., Pépés, S. E., Babourina-Brooks, B., Chen, C., Kim, S., Sigurdsson, H. P., Draper, A., Husain, M., Nachev, P., Gowland, P., Morris, P. G., & Jackson, S. R. (2021). Acute gabapentin administration in healthy adults. A double-blind placebo-controlled study using transcranial magnetic stimulation and 7T 1H-MRS. NeuroImage: Reports, 1(1), Article 100003. https://doi.org/10.1016/j.ynirp.2021.100003

Developing the Premonitory Urges for Tic Disorders Scale–Revised (PUTS-R) (2020)
Journal Article
Baumung, L., Brandt, V., Müller-Vahl, K., Jackson, G., Jackson, S., Dyke, K., Münchau, A., & Golm, D. (2021). Developing the Premonitory Urges for Tic Disorders Scale–Revised (PUTS-R). Journal of Neuropsychology, 15(1), 129-142. https://doi.org/10.1111/jnp.12216

Background: Patients with Gilles de la Tourette syndrome (GTS) or chronic tic disorders frequently experience premonitory urges prior to tics. The ‘Premonitory Urges for Tic Disorders Scale’ (PUTS) is commonly used in order to assess urge severity in... Read More about Developing the Premonitory Urges for Tic Disorders Scale–Revised (PUTS-R).

Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome (2020)
Journal Article
Morera Maiquez, B., Sigurdsson, H. P., Dyke, K., Clarke, E., McGrath, P., Pasche, M., Rajendran, A., Jackson, G. M., & Jackson, S. R. (2020). Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome. Current Biology, 30(12), 2334-2342.e3. https://doi.org/10.1016/j.cub.2020.04.044

Tourette syndrome (TS) is a neuropsychiatric disorder characterised by the occurrence of vocal and motor tics. Tics are involuntary, repetitive, movements and vocalisations that occur in bouts, typically many times in a single day, and are often prec... Read More about Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome.

A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation (2020)
Journal Article
Sigurdsson, H. P., Jackson, G. M., Jackson, S. R., Dyke, K., & Kim, S. (2020). A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation. Cortex, 129, 175-187. https://doi.org/10.1016/j.cortex.2020.04.014

Tourette syndrome (TS) is a hyperkinetic movement disorder characterised by the occurrence of chronic motor and vocal tics, and is associated with alterations in the balance of excitatory and inhibitory signalling within key brain networks; in partic... Read More about A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation.

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2020)
Preprint / Working Paper
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterised by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

The role of the insula in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2020)
Journal Article
Jackson, S. R., Loayza, J., Crighton, M., Sigurdsson, H. P., Dyke, K., & Jackson, G. M. (2020). The role of the insula in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome. Cortex, 126, 119-133. https://doi.org/10.1016/j.cortex.2019.12.021

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterised by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the insula in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome (2019)
Journal Article
Dyke, K., Jackson, G. M., Nixon, E., & Jackson, S. R. (2019). Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome. Experimental Brain Research, 237(11), 2853–2863. https://doi.org/10.1007/s00221-019-05637-5

Tourette syndrome is a neurodevelopmental disorder characterised by motor and phonic tics. For some, tics can be managed using medication and/or forms of behavioural therapy, however, adverse side effects and access to specialist resources can be bar... Read More about Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome.

Impaired forward model updating in young adults with Tourette syndrome (2018)
Journal Article
Kim, S., Jackson, G. M., Dyke, K., & Jackson, S. R. (2019). Impaired forward model updating in young adults with Tourette syndrome. Brain, 142(1), 209-219. https://doi.org/10.1093/brain/awy306

Current theories of motor control emphasise how the brain may use internal models of the body to ensure accurate planning and control of movements. One such internal model - a forward model - is thought to generate an estimate of the next motor state... Read More about Impaired forward model updating in young adults with Tourette syndrome.

Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI (2017)
Journal Article
Dyke, K., Pépés, S. E., Chen, C., Kim, S., Sigurdsson, H. P., Draper, A., Husain, M., Nachev, P., Gowland, P. A., Morris, P. G., & Jackson, S. R. (2017). Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI. NeuroImage, 152, 360-370. https://doi.org/10.1016/j.neuroimage.2017.03.011

Imbalances in glutamatergic (excitatory) and GABA (inhibitory) signalling within key brain networks are thought to underlie many brain and mental health disorders, and for this reason there is considerable interest in investigating how individual var... Read More about Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI.

Intra-Subject Consistency and Reliability of Response Following 2 mA Transcranial Direct Current Stimulation (2016)
Journal Article
Dyke, K., Kim, S., Jackson, G. M., & Jackson, S. R. (2016). Intra-Subject Consistency and Reliability of Response Following 2 mA Transcranial Direct Current Stimulation. Brain Stimulation, 9(6), 819-825. https://doi.org/10.1016/j.brs.2016.06.052

Background

Transcranial direct current stimulation (tDCS) is a popular non-invasive brain stimulation technique that has been shown to influence cortical excitability. While polarity specific effects have often been reported, this is not always th... Read More about Intra-Subject Consistency and Reliability of Response Following 2 mA Transcranial Direct Current Stimulation.