Mrs POOJITHA RAJASEKAR's Outputs (3)

Interplay between genetics and epigenetics in lung fibrosis (2025)
Journal Article
Valand, A., Rajasekar, P., Wain, L. V., & Clifford, R. L. (2025). Interplay between genetics and epigenetics in lung fibrosis. International Journal of Biochemistry and Cell Biology, 180, Article 106739. https://doi.org/10.1016/j.biocel.2025.106739

Lung fibrosis, including idiopathic pulmonary fibrosis (IPF), is a complex and devastating disease characterised by the progressive scarring of lung tissue leading to compromised respiratory function. Aberrantly activated fibroblasts deposit extracel... Read More about Interplay between genetics and epigenetics in lung fibrosis.

Mepolizumab Induced Changes in Nasal Methylome and Transcriptome to Predict Response in Asthma (2024)
Journal Article
Rakkar, K., Pang, Y. L., Rajasekar, P., Portelli, M. A., Hall, R. J., Clifford, R. L., Shaw, D., & Sayers, I. (2024). Mepolizumab Induced Changes in Nasal Methylome and Transcriptome to Predict Response in Asthma. American Journal of Respiratory and Critical Care Medicine, 209(10), 1268-1272. https://doi.org/10.1164/rccm.202308-1477le

Nepalese indoor cookstove smoke extracts alter human airway epithelial gene expression, DNA methylation and hydroxymethylation (2023)
Journal Article
Rajasekar, P., Hall, R. J., Binaya, K., Mahapatra, P. S., Puppala, S. P., Thakker, D., MacIsaac, J. L., Lin, D., Kobor, M., Bolton, C. E., Sayers, I., Hall, I. P., & Clifford, R. L. (2023). Nepalese indoor cookstove smoke extracts alter human airway epithelial gene expression, DNA methylation and hydroxymethylation. Environmental Pollution, 337, Article 122561. https://doi.org/10.1016/j.envpol.2023.122561

Household air pollution caused by inefficient cooking practices causes 4 million deaths a year worldwide. In Nepal, 86% of the rural population use solid fuels for cooking. Over 25% of premature deaths associated with air pollution are respiratory in... Read More about Nepalese indoor cookstove smoke extracts alter human airway epithelial gene expression, DNA methylation and hydroxymethylation.