Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes
(2020)
Journal Article
Zoltner, M., Campagnaro, G. D., Taleva, G., Burrell, A., Cerone, M., Leung, K. F., Achcar, F., Horn, D., Vaughan, S., Gadelha, C., Zíková, A., Barrett, M. P., de Koning, H. P., & Field, M. C. (2020). Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes. Journal of Biological Chemistry, 295(24), 8331-8347. https://doi.org/10.1074/jbc.ra120.012355
© 2020 Zoltner et al. Introduced about a century ago, suramin remains a frontline drug for the management of early-stage East African trypanosomiasis (sleeping sickness). Cellular entry into the causative agent, the protozoan parasite Trypanosoma bru... Read More about Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes.