JOHN WILLIAMS's Outputs (5)

Associations between plasma branched chain amino acids and health biomarkers in response to resistance exercise training across age (2020)
Journal Article
Sayda, M. H., Phillips, B. E., Williams, J. P., Greenhaff, P. L., Wilkinson, D. J., Smith, K., & Atherton, P. J. (2020). Associations between plasma branched chain amino acids and health biomarkers in response to resistance exercise training across age. Nutrients, 12(10), Article 3029. https://doi.org/10.3390/nu12103029

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Leucine, isoleucine and valine (i.e., the branched chain amino acids, BCAA) play a key role in the support and regulation of tissue protein regulation and also as energy substrates. However, p... Read More about Associations between plasma branched chain amino acids and health biomarkers in response to resistance exercise training across age.

Glucagon-like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle (2020)
Journal Article
Abdulla, H., Phillips, B. E., Wilkinson, D. J., Limb, M., Jandova, T., Bass, J. J., …Atherton, P. J. (2020). Glucagon-like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle. Aging Cell, 19(9), Article e13202. https://doi.org/10.1111/acel.13202

© 2020 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd Background: Despite its known insulin-independent effects, glucagon-like peptide-1 (GLP-1) role in muscle protein turnover has not been explored under fed-stat... Read More about Glucagon-like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle.

Funnel plots may show asymmetry in the absence of publication bias with continuous outcomes dependent on baseline risk: presentation of a new publication bias test (2020)
Journal Article
Doleman, B., Freeman, S. C., Lund, J. N., Williams, J. P., & Sutton, A. J. (2020). Funnel plots may show asymmetry in the absence of publication bias with continuous outcomes dependent on baseline risk: presentation of a new publication bias test. Research Synthesis Methods, 11(4), 522-534. https://doi.org/10.1002/jrsm.1414

This study aimed to determine for continuous outcomes dependent on baseline risk, whether funnel plot asymmetry may be due to statistical artefact rather than publication bias and evaluate a novel test to resolve this. Firstly, we conducted assessmen... Read More about Funnel plots may show asymmetry in the absence of publication bias with continuous outcomes dependent on baseline risk: presentation of a new publication bias test.

Trainee-led emergency laparotomy operating (2020)
Journal Article
Boyd-Carson, H., Doleman, B., Lockwood, S., Williams, J. P., Tierney, G. M., & Lund, J. N. (2020). Trainee-led emergency laparotomy operating. British Journal of Surgery, 107(10), 1289-1298. https://doi.org/10.1002/bjs.11611

© 2020 BJS Society Ltd Published by John Wiley & Sons Ltd Background: To achieve completion of training in general surgery, trainees are required to demonstrate competency in common procedures performed at emergency laparotomy. The aim of this stud... Read More about Trainee-led emergency laparotomy operating.

Network analysis of human muscle adaptation to aging and contraction (2020)
Journal Article
Etheridge, T., Willis, C., Atherton, P., Ames, R., Szewczyk, N., Deane, C., …Lund, J. (2020). Network analysis of human muscle adaptation to aging and contraction. Aging, 12(1), 740-755. https://doi.org/10.18632/aging.102653

Resistance exercise (RE) remains a primary approach for minimising aging muscle decline. Understanding muscle adaptation to individual contractile components of RE (eccentric, concentric) might optimise RE-based intervention strategies. Herein, we em... Read More about Network analysis of human muscle adaptation to aging and contraction.