Dr GIUSEPPE MANTOVANI's Outputs (2)

Synthetic macromolecular peptide-mimetics with amino acid substructure residues as protein stabilising excipients (2023)
Journal Article
Foralosso, R., Kopiasz, R. J., Mantovani, G., Stolnik, S., & Alexander, C. (2024). Synthetic macromolecular peptide-mimetics with amino acid substructure residues as protein stabilising excipients. Journal of Materials Chemistry B, 12, 1022-1030. https://doi.org/10.1039/d3tb02102e

The clinical use of protein and peptide biotherapeutics requires fabrication of stable products. This particularly concerns stability towards aggregation of proteins or peptides. Here, we tested a hypothesis that interactions between a synthetic pept... Read More about Synthetic macromolecular peptide-mimetics with amino acid substructure residues as protein stabilising excipients.

Biotin receptor-mediated intracellular delivery of synthetic polypeptide-protein complexes (2023)
Journal Article
Li, H., Bruce, G., Childerhouse, N., Keegan, G., Mantovani, G., & Stolnik, S. (2023). Biotin receptor-mediated intracellular delivery of synthetic polypeptide-protein complexes. Journal of Controlled Release, 357, 333-341. https://doi.org/10.1016/j.jconrel.2023.03.051

Pulmonary delivery offers a non-invasive route for the administration of biotherapeutics. In this context, understanding and control of a transport into, and across cellular barriers is central to the design of delivery systems. Here, we report our s... Read More about Biotin receptor-mediated intracellular delivery of synthetic polypeptide-protein complexes.