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Dr RACHEL CLIFFORD's Outputs (5)

Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function (2012)
Journal Article
Clifford, R. L., Singer, C. A., & John, A. E. (2013). Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function. Pulmonary Pharmacology and Therapeutics, 26(1), 75-85. https://doi.org/10.1016/j.pupt.2012.07.002

Regulation of phenotypic plasticity in smooth muscle requires an understanding of the mechanisms regulating phenotype-specific genes and the processes dysregulated during pathogenesis. Decades of study in airway smooth muscle has provided extensive k... Read More about Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function.

Abnormal Histone Methylation Is Responsible for Increased Vascular Endothelial Growth Factor 165a Secretion from Airway Smooth Muscle Cells in Asthma (2012)
Journal Article
Clifford, R. L., John, A. E., Brightling, C. E., & Knox, A. J. (2012). Abnormal Histone Methylation Is Responsible for Increased Vascular Endothelial Growth Factor 165a Secretion from Airway Smooth Muscle Cells in Asthma. Journal of Immunology, 189(2), 819-831. https://doi.org/10.4049/jimmunol.1103641

Vascular endothelial growth factor (VEGF), a key angiogenic molecule, is aberrantly expressed in several diseases including asthma where it contributes to bronchial vascular remodeling and chronic inflammation. Asthmatic human airway smooth muscle ce... Read More about Abnormal Histone Methylation Is Responsible for Increased Vascular Endothelial Growth Factor 165a Secretion from Airway Smooth Muscle Cells in Asthma.