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Professor RICHARD GRUNDY's Outputs (3)

European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence (2025)
Journal Article
Simon, A. R. S., Ritzmann, T. A., Obrecht-Sturm, D., Benesch, M., Timmermann, B., Leblond, P., Kilday, J.-P., Poggi, G., Thorp, N., Massimino, M., van Veelen, M.-L., Schuhmann, M., Thomale, U.-W., Tippelt, S., Schüller, U., Rutkowski, S., Grundy, R. G., Bolle, S., Fernández-Teijeiro, A., & Pajtler, K. W. (2025). European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence. EJC Paediatric Oncology, 5, Article 100227. https://doi.org/10.1016/j.ejcped.2025.100227

Ependymomas are tumors of glial origin representing the second most common malignant brain tumors of childhood. Peak incidence in childhood is under 3 years of age. Most paediatric ependymomas arise intracranially and are molecularly divided into fou... Read More about European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence.

Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review (2025)
Journal Article
AlMutairi, H., Mccullough, F., Siddiqui, K., Ghemlas, I., AlHarbi, M., Grundy, R., & Dandapani, M. (2025). Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review. Journal of Nutrition and Metabolism, https://doi.org/10.1155/jnme/7935879

Background: Evidence suggests the positive effects of ketogenic diet (KD) on cancers by limiting glucose availability to cancer cells. This systematic review aimed to explore the safety, feasibility, and effectiveness of KD in children with brain tum... Read More about Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review.

Cognitive Outcomes in Children Treated for Ependymoma Diagnosed Under 36 Months: A Systematic Review (2025)
Journal Article
Thomas, S., Morley, E., Ritzmann, T., Clayton, C., Powers, K., Airdrie, J., Robinson, L., Fifield, K., Packham, A., Oprandi, M. C., Lui, J., Whitfield, G., Thorp, N., Limond, J., & Grundy, R. (in press). Cognitive Outcomes in Children Treated for Ependymoma Diagnosed Under 36 Months: A Systematic Review. Pediatric Blood and Cancer, Article e31588. https://doi.org/10.1002/pbc.31588

It is crucial to understand the morbidity associated with treatments for young children with ependymoma given this is a high incidence age group also known to be at risk of poorer cognitive outcomes. This review aimed to identify the quality of exist... Read More about Cognitive Outcomes in Children Treated for Ependymoma Diagnosed Under 36 Months: A Systematic Review.