Professor AMIR GHAEMMAGHAMI's Outputs (2)

The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent (2012)
Journal Article
Al-Ghouleh, A., Johal, R., Sharquie, I. K., Emara, M., Harrington, H., Shakib, F., & Ghaemmaghami, A. M. (2012). The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent. PLoS ONE, 7(3), Article 11. https://doi.org/10.1371/journal.pone.0033929

Allergens are initiators of both innate and adaptive immune responses. They are recognised at the site of entry by epithelial and dendritic cells (DCs), both of which activate innate inflammatory circuits that can collectively induce Th2 immune respo... Read More about The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent.

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite (2012)
Journal Article
Emara, M., Royer, P.-J., Mahdavi, J., Shakib, F., & Ghaemmaghami, A. M. (2012). Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite. Journal of Biological Chemistry, 287(8), https://doi.org/10.1074/jbc.M111.312520

Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance of immune responses to microbial pathogens as well as to allergens, but the exact mechanisms of their involvement in allergic responses and Th2 cell differenti... Read More about Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.