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Professor CHRIS HOLLIS's Outputs (9)

Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial (2022)
Journal Article
Andrén, P., Holmsved, M., Ringberg, H., Wachtmeister, V., Isomura, K., Aspvall, K., Lenhard, F., Hall, C. L., Davies, B., Murphy, T., Hollis, C., Sampaio, F., Feldman, I., Bottai, M., Serlachius, E., Andersson, E., Fernández De La Cruz, L., & Mataix-Cols, D. (2022). Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial. JAMA Network Open, 5(8), Article e2225614. https://doi.org/10.1001/jamanetworkopen.2022.25614

Importance: The availability of behavior therapy for individuals with Tourette syndrome (TS) and chronic tic disorder (CTD) is limited. Objective: To determine the efficacy and cost-effectiveness of internet-delivered exposure and response prevention... Read More about Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial.

Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals (2022)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & RADAR-CNS Consortium. (2022). Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals. BMC Medical Informatics and Decision Making, 22(1), Article 125. https://doi.org/10.1186/s12911-022-01856-z

BACKGROUND: Epilepsy, multiple sclerosis(MS) and depression are long term, central nervous system disorders which have a significant impact on everyday life. Evaluating symptoms of these conditions is problematic and typically involves repeated visit... Read More about Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals.

The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study (2022)
Journal Article
Hall, C. L., Marston, L., Khan, K., Brown, B. J., Sanderson, C., Andrén, P., Bennett, S., Heyman, I., Mataix-Cols, D., Serlachius, E., Hollis, C., & Murphy, T. (2023). The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study. Child Psychiatry and Human Development, 54(6), 1499–1509. https://doi.org/10.1007/s10578-022-01348-1

To understand how children and young people with tic disorders were affected by COVID-19, we compared pre and during pandemic scores on the Yale Global Tic Severity Scale (YGTSS). Participants were young people (N = 112; male:78%; 9–17 years) randomi... Read More about The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study.

Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses (2022)
Journal Article
Freeman, D., Lambe, S., Kabir, T., Petit, A., Rosebrock, L., Yu, L.-M., Dudley, R., Chapman, K., Morrison, A., O'Regan, E., Aynsworth, C., Jones, J., Murphy, E., Powling, R., Galal, U., Grabey, J., Rovira, A., Martin, J., Hollis, C., Clark, D. M., …West, J. (2022). Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses. Lancet Psychiatry, 9(5), 375-388. https://doi.org/10.1016/S2215-0366%2822%2900060-8

Background
Automated delivery of psychological therapy using immersive technologies such as virtual reality (VR) might greatly increase the availability of effective help for patients. We aimed to evaluate the efficacy of an automated VR cognitive t... Read More about Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses.

Factors influencing the efficacy of an online behavioural intervention for children and young people with tics: Process evaluation of a randomised controlled trial (2022)
Journal Article
Khan, K., Hollis, C., Hall, C. L., Davies, E. B., Murray, E., Andrén, P., Mataix-Cols, D., Murphy, T., & Glazebrook, C. (2022). Factors influencing the efficacy of an online behavioural intervention for children and young people with tics: Process evaluation of a randomised controlled trial. Journal of Behavioral and Cognitive Therapy, 32(3), 197-206. https://doi.org/10.1016/j.jbct.2022.02.005

The Online Remote Behavioural Intervention for Tics (ORBIT) trial found that an internet-delivered, therapist-supported, and parent-assisted Exposure and Response Prevention (ERP) intervention reduced tic severity and improved clinical outcomes. This... Read More about Factors influencing the efficacy of an online behavioural intervention for children and young people with tics: Process evaluation of a randomised controlled trial.

Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., & Coupland, C. (2022). Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records. Evidence-Based Mental Health, 25(4), 169-176. https://doi.org/10.1136/ebmental-2021-300355

BACKGROUND: Studies report an increased risk of self-harm or suicide in people prescribed mirtazapine compared with other antidepressants. OBJECTIVES: To compare the risk of serious self-harm in people prescribed mirtazapine versus other antidepressa... Read More about Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records.

The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., Hippisley-Cox, J., & Coupland, C. (2022). The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records. BMC Medicine, 20(1), Article 43. https://doi.org/10.1186/s12916-022-02247-x

Background
Studies have reported an increased risk of mortality among people prescribed mirtazapine compared to other antidepressants. The study aimed to compare all-cause and cause-specific mortality between adults prescribed mirtazapine or other s... Read More about The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records.

Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply (2022)
Journal Article
Hollis, C., Hall, C. L., Marston, L., & ORBIT Trial Team. (2022). Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply. Lancet Psychiatry, 9(2), 106-107. https://doi.org/10.1016/S2215-0366%2821%2900503-4

We thank Qianzhi Wang and colleagues for their endorsement of the ORBIT trial1, 2 and for acknowledging the importance of the findings. We are grateful for the opportunity to clarify the issue of adherence within the trial, which we believe to be a... Read More about Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply.