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Professor HARMINDER DUA's Outputs (56)

Pre-Descemet's endothelial keratoplasty (PDEK) (2014)
Journal Article
Dua, H., Agarwal, A., Narang, P., Kumar, D. A., Agarwal, A., Jacob, S., Agarwal, A., & Gupta, A. (2014). Pre-Descemet's endothelial keratoplasty (PDEK). British Journal of Ophthalmology, 98(9), 1181-1185. https://doi.org/10.1136/bjophthalmol-2013-304639

A new surgical technique for endothelial keratoplasty is described, in which the composite of pre-Descemet's layer (Dua's layer) with Descemet's membrane and endothelium is transplanted subsequent to the removal of the recipient's Descemet's membrane... Read More about Pre-Descemet's endothelial keratoplasty (PDEK).

Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting (2014)
Journal Article
Dua, H., Said, D., Elalfy, M., Gatzioufas, Z., El-Zakzouk, E., Hassan, M., Saif, M., Zaki, A., & Hafezi, F. (2014). Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting. Ophthalmology: Journal of The American Academy of Ophthalmology, 121(7), 1377-1382. https://doi.org/10.1016/j.ophtha.2014.01.011

Concise review: evidence for CD34 as a common marker for diverse progenitors (2014)
Journal Article
Sidney, L. E., Branch, M. J., Dunphy, S. E., Dua, H. S., & Hopkinson, A. (2014). Concise review: evidence for CD34 as a common marker for diverse progenitors. STEM CELLS, 32(6), 1380-1389. https://doi.org/10.1002/stem.1661

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and progenitor cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants. Due to these historical... Read More about Concise review: evidence for CD34 as a common marker for diverse progenitors.

Corneal Densitometry as an Indicator of Corneal Health (2011)
Journal Article
Otri, A. M., Fares, U., Al-Aqaba, M. A., & Dua, H. S. (2012). Corneal Densitometry as an Indicator of Corneal Health. Ophthalmology: Journal of The American Academy of Ophthalmology, 119(3), 501-508. https://doi.org/10.1016/j.ophtha.2011.08.024

Purpose
To establish prospectively the normal values of corneal density of healthy subjects using the Pentacam Scheimpflug system (Oculus, Inc., Wetzlar, Germany) and to investigate alteration in corneal density during active and healed stages of ba... Read More about Corneal Densitometry as an Indicator of Corneal Health.

Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis (2011)
Journal Article
Mohammed, I., Abedin, A., Tsintzas, K., Abedin, S. A., Otri, A. M., Hopkinson, A., Mathew, M., & Dua, H. S. (2011). Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis. Cornea, 30(8), 899-904. https://doi.org/10.1097/ICO.0b013e31820126e5

Purpose:

Antimicrobial peptides (AMPs) and toll-like receptors (TLRs) form part of the “chemical barrier” of the ocular surface to microbes. Evidence suggests that pathogen recognition by TLR releases AMPs, altering AMP-TLR profiles in pathologic... Read More about Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis.

Signalling pathways involved in ribonuclease-7 expression (2010)
Journal Article
Mohammed, I., Yeung, A., Abedin, A., Hopkinson, A., & Dua, H. S. (2011). Signalling pathways involved in ribonuclease-7 expression. Cellular and Molecular Life Sciences, 68(11), 1941-1952. https://doi.org/10.1007/s00018-010-0540-2

Antimicrobial peptides are host defence molecules that play a potential role in preventing infection at the epithelial surfaces. Ribonuclease (RNase)-7 has been shown to possess a broad spectrum of microbicidal activity against various pathogens. Her... Read More about Signalling pathways involved in ribonuclease-7 expression.

Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium (2010)
Journal Article
Mohammed, I., Suleman, H., Otri, A. M., Kulkarni, B. B., Chen, P., Hopkinson, A., & Dua, H. S. (2010). Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium. Investigative Ophthalmology & Visual Science, 51(9), 4677-4682. https://doi.org/10.1167/iovs.10-5334

Purpose: Antimicrobial peptides (AMPs) are multifunctional host defense molecules. Human β-defensin 9 (HBD9) has previously been shown to be downregulated during ocular surface (OS) infection or inflammation. Here, the authors aimed to study localiz... Read More about Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium.

Epidermal Growth Factor Variations in Amniotic Membrane Used for Ex Vivo Tissue Constructs (2009)
Journal Article
Gicquel, J.-J., Dua, H. S., Brodie, A., Mohammed, I., Suleman, H., Lazutina, E., James, D. K., & Hopkinson, A. (2009). Epidermal Growth Factor Variations in Amniotic Membrane Used for Ex Vivo Tissue Constructs. Tissue Engineering Part A, 15(8), 1919-1927. https://doi.org/10.1089/ten.tea.2008.0432

Introduction: The amniotic membrane (AM) is used for engineering ex vivo tissue constructs used in ocular surface reconstruction. Epidermal growth factor (EGF) content of the AM is believed to play a key role in supporting corneal epithelial cell exp... Read More about Epidermal Growth Factor Variations in Amniotic Membrane Used for Ex Vivo Tissue Constructs.

A novel antimicrobial peptide on the ocular surface shows decreased expression in inflammation and infection (2008)
Journal Article
Abedin, A., Mohammed, I., Hopkinson, A., & Dua, H. S. (2008). A novel antimicrobial peptide on the ocular surface shows decreased expression in inflammation and infection. Investigative Ophthalmology & Visual Science, 49(1), 28-33. https://doi.org/10.1167/iovs.07-0645

PURPOSE: Antimicrobial peptides (AMPs) are cationic host defense peptides with microbicidal and cell-signaling properties. They show promise as potential therapeutic agents. In the present study, a beta-defensin AMP gene was isolated from the ocular... Read More about A novel antimicrobial peptide on the ocular surface shows decreased expression in inflammation and infection.