All Outputs (45313)

Digital ecologies in practice (2024)
Journal Article
Hartman Davies, O., Turnbull, J., & Searle, A. (2024). Digital ecologies in practice. cultural geographies, https://doi.org/10.1177/14744740241269172

Digital mediation profoundly shapes how cultural geographers understand and encounter nature. Practice-based engagements with digitally mediated natures pose methodological, aesthetic and ethical questions for cultural geographers. Reflecting on a co... Read More about Digital ecologies in practice.

Natural product pharmacology: the British Journal of Pharmacology perspective (2024)
Journal Article
Wang, X., Izzo, A. A., Papapetropoulos, A., Alexander, S. P. H., Cortese‐Krott, M., Kendall, D. A., Martemyanov, K. A., Mauro, C., Panettieri, R. A., Patel, H. H., Schulz, R., Stefanska, B., Stephens, G. J., Teixeira, M. M., Vergnolle, N., & Ferdinandy, P. (2024). Natural product pharmacology: the British Journal of Pharmacology perspective. British Journal of Pharmacology, https://doi.org/10.1111/bph.17300

Natural products (NPs) have long been used as a rich source of bioactive compounds for drug development. Recent technological advancements have revitalised natural products research as evidenced by increased publications in this field. In this editor... Read More about Natural product pharmacology: the British Journal of Pharmacology perspective.

‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse (2024)
Journal Article
Martin, P. R. (2024). ‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse. cultural geographies, https://doi.org/10.1177/14744740241269142

This article seeks to advance recent literatures exploring the important role of poetry in the production and circulation of geographical knowledge. It does this by critically analysing a poem that was written by the traveller and scholar Wiliam Heal... Read More about ‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse.

The role of the ALKBH5 RNA demethylase in invasive breast cancer (2024)
Journal Article
Woodcock, C. L., Alsaleem, M., Toss, M. S., Lothion-Roy, J., Harris, A. E., Jeyapalan, J. N., Blatt, N., Rizvanov, A. A., Miftakhova, R. R., Kariri, Y. A., Madhusudan, S., Green, A. R., Rutland, C. S., Fray, R. G., Rakha, E. A., & Mongan, N. P. (2024). The role of the ALKBH5 RNA demethylase in invasive breast cancer. Discover Oncology, 15(1), Article 343. https://doi.org/10.1007/s12672-024-01205-8

Background: N6-methyladenosine (m6A) is the most common internal RNA modification and is involved in regulation of RNA and protein expression. AlkB family member 5 (ALKBH5) is a m6A demethylase. Given the important role of m6A in biological mechanism... Read More about The role of the ALKBH5 RNA demethylase in invasive breast cancer.

Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain (2024)
Journal Article
Zeng, L., Engels, S., Swann, G. E., Chen, X., Huang, X., Cao, Y., & McGowan, S. (2024). Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain. Journal of Hydrology, 641, Article 131839. https://doi.org/10.1016/j.jhydrol.2024.131839

Dam construction for social-economic benefits has raised substantial biological and ecological concerns. However, contrasting findings have been reported regarding the role of hydrological modification in floodplain lake ecosystems. Here, we evaluate... Read More about Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain.

Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial (2024)
Journal Article
Sharpe, M., Walker, J., van Niekerk, M., Toynbee, M., Magill, N., Frost, C., White, I. R., Walker, S., Duarte, A., Owens, C., Dickens, C., Price, A., Sharpe, M., Walker, J., van Niekerk, M., Toynbee, M., Magill, N., Frost, C., White, I. R., Walker, S., …Yousif, M. (2024). Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial. Lancet Psychiatry, 11(9), 684-695. https://doi.org/10.1016/s2215-0366%2824%2900188-3

Background: Older people admitted to hospital in an emergency often have prolonged inpatient stays that worsen their outcomes, increase health-care costs, and reduce bed availability. Growing evidence suggests that the biopsychosocial complexity of t... Read More about Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial.

Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing? (2024)
Journal Article
Ogunbode, C. A., Salmela-Aro, K., Maran, D. A., van den Broek, K., Doran, R., Lins, S., Torres-Marín, J., Navarro-Carrillo, G., Rocchi, G., & Schermer, J. A. (2024). Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing?. Journal of Affective Disorders, 364, 37-40. https://doi.org/10.1016/j.jad.2024.08.018

Background: Research on the nature and prevalence of phenomena like climate anxiety (or eco-anxiety) is increasing rapidly but there is little understanding of the conditions under which climate change worry becomes more or less likely to significant... Read More about Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing?.

Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data (2024)
Journal Article
CIPOLLETTA, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A., Mamas, M., Choi, H., Tata, L., & Abhishek, A. (in press). Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data. The Lancet Rheumatology,

Background Starting urate-lowering therapy (ULT) may trigger gout flares. Gout flares have been temporally associated with an increased risk of cardiovascular events (CVEs).
Objective To estimate the risk of CVEs among patients with gout initiating... Read More about Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data.

Determination of hATG8 Binding Selectivity of AIM (Autophagy-Interacting Motif) Peptides Using Native Electrospray Ionization Mass Spectrometry (2024)
Book Chapter
Brennan, A., Oldham, N., Layfield, R., & Scott, D. (2024). Determination of hATG8 Binding Selectivity of AIM (Autophagy-Interacting Motif) Peptides Using Native Electrospray Ionization Mass Spectrometry. In I. P. Nezis (Ed.), Selective autophagy: methods and protocols (237-246). Springer. https://doi.org/10.1007/978-1-0716-4067-8_19

Establishing the hATG8 binding selectivity of AIM (autophagy-interacting motif) sequences found within autophagy system proteins provides insights into their biological roles, and in the case of disease-associated AIM mutations, potential pathophysio... Read More about Determination of hATG8 Binding Selectivity of AIM (Autophagy-Interacting Motif) Peptides Using Native Electrospray Ionization Mass Spectrometry.

Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance (2024)
Journal Article
Heydon, J., Chakraborty, R., Patel, V., Wood, C., Wood, M., & Bunce, C. (2024). Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance. Environmental Management, https://doi.org/10.1007/s00267-024-02014-z

Domestic combustion emissions pose a growing risk to public health, especially in the UK. Existing responses are polarised, with government advocating use of lower emission fuels and stoves while clean air campaigners call for blanket bans on burning... Read More about Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance.

A systematic review of physical activity and nutritional interventions for the management of normal weight and overweight obesity (2024)
Journal Article
Jacob, E., Moura, A., & Avery, A. (2024). A systematic review of physical activity and nutritional interventions for the management of normal weight and overweight obesity. Nutrition, Metabolism and Cardiovascular Diseases, https://doi.org/10.1016/j.numecd.2024.08.001

Aims: Normal Weight Obesity (NWO) and Overweight Obesity (OWO) are prevalent conditions, yet knowledge of management is limited. This review aims to assess the effectiveness of physical activity and nutritional interventions in the management of NWO... Read More about A systematic review of physical activity and nutritional interventions for the management of normal weight and overweight obesity.

The Conversationality Index: A quantitative assessment of conversation in social media interactions (2024)
Journal Article
Cotgrove, L., Thul, R., & Conklin, K. (in press). The Conversationality Index: A quantitative assessment of conversation in social media interactions. Internet Pragmatics,

There has been an explosion in social media use, with Statista estimating that worldwide, Facebook has over 3 billion regular active users, YouTube 2.5 billion, and Instagram and WhatsApp 2 billion. While social media allows one to connect and intera... Read More about The Conversationality Index: A quantitative assessment of conversation in social media interactions.

Cost-effectiveness of HCC Surveillance Strategies in Patients With Compensated Liver Cirrhosis in the United Kingdom (2024)
Journal Article
Garay, O. U., Ambühl, L. E., Bird, T. G., Barnes, E., Irving, W. L., Walkley, R., & Rowe, I. A. (2024). Cost-effectiveness of HCC Surveillance Strategies in Patients With Compensated Liver Cirrhosis in the United Kingdom. Value in Health, https://doi.org/10.1016/j.jval.2024.07.015

This study aimed to evaluate the cost-effectiveness (CE) of four hepatocellular carcinoma (HCC) surveillance strategies in the UK, the GAAD algorithm, which combines gender (biological sex) and age with Elecsys® biomarker assays, alpha-fetoprotein (A... Read More about Cost-effectiveness of HCC Surveillance Strategies in Patients With Compensated Liver Cirrhosis in the United Kingdom.

Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor (2024)
Journal Article
Egun, I. L., Akinwolemiwa, B., Yin, B., Tian, H., He, H., Fow, K. L., Zhang, H., Chen, G. Z., & Hu, D. (2024). Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor. Bioresource Technology, 409, 131251. https://doi.org/10.1016/j.biortech.2024.131251

Biomass-derived carbon for supercapacitors faces the challenge of achieving hierarchical porous carbon with graphitic structure and specific heteroatoms through a single-stage thermal process that minimises resource input. Herein, molten base carboni... Read More about Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor.

2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy (2024)
Journal Article
Das, S., McIvor, C., Greener, A., Suwita, C., Argent, S. P., & O'Duill, M. L. (2024). 2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy. Angewandte Chemie, https://doi.org/10.1002/anie.202410954

The 2,2-difluoroethyl group is an important lipophilic hydrogen bond donor in medicinal chemistry, but its incorporation into small molecules is often challenging. Herein, we demonstrate electrophilic 2,2-difluoroethylation of thiol, amine and alcoho... Read More about 2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy.

Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain (2024)
Journal Article
Brown, J. A., Hughes, A., Bhutta, M. F., Trautrims, A., & Trueba, M. L. (2024). Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain. Competition and Change, https://doi.org/10.1177/10245294241272190

Drawing on research into medical gloves global value chains (GVCs), this article examines the interacting roles that states differently positioned in GVCs have played in preventing and eliminating forced labour. Our case study, based on a worker surv... Read More about Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain.

Bringing the voice of social housing tenants into shaping the health and care research agenda (2024)
Journal Article
Phillips, O. R., Mardell, D., Stephenson, K., Hussain, S., Burton, D., Bernard, B., Stevenson, S., & Morling, J. R. (2024). Bringing the voice of social housing tenants into shaping the health and care research agenda. Research Involvement and Engagement, 10, Article 85. https://doi.org/10.1186/s40900-024-00613-y

Background: A larger percentage of social housing tenants have poorer physical and mental health outcomes compared to private renters and homeowners. They are also at a greater risk of respiratory conditions, cardiovascular disease, communicable dise... Read More about Bringing the voice of social housing tenants into shaping the health and care research agenda.

Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials (2024)
Journal Article
Jackson, J., Moreton, J., Barnett, N., & Hurst, M. (2024). Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials. Journal of Research in Nursing,

Background
The methodologies for clinical research trials are evolving to greater usage of social media platforms, providing opportunities to incorporate smart technologies in their delivery. Research Nurses should consider how they can utilise pla... Read More about Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials.

Identifying tinnitus in mice by tracking the motion of body markers in response to an acoustic startle (2024)
Journal Article
Wallace, M. N., Berger, J. I., Hockley, A., Sumner, C. J., Akeroyd, M. A., Palmer, A. R., & McNaughton, P. A. (2024). Identifying tinnitus in mice by tracking the motion of body markers in response to an acoustic startle. Frontiers in Neuroscience, 18, Article 1452450. https://doi.org/10.3389/fnins.2024.1452450

Rodent models of tinnitus are commonly used to study its mechanisms and potential treatments. Tinnitus can be identified by changes in the gap-induced prepulse inhibition of the acoustic startle (GPIAS), most commonly by using pressure detectors to m... Read More about Identifying tinnitus in mice by tracking the motion of body markers in response to an acoustic startle.

Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement (2024)
Journal Article
Ball, J. D., Hills, E., Altaf, A., Ramesh, P., Green, M., Surti, F. B., Minhas, J. S., Robinson, T. G., Bond, B., Lester, A., Hoiland, R., Klein, T., Liu, J., Nasr, N., Junejo, R. T., Müller, M., Lecchini-Visintini, A., Mitsis, G., Burma, J. S., Smirl, J. D., …Beishon, L. . C. (2024). Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement. Journal of Cerebral Blood Flow and Metabolism, https://doi.org/10.1177/0271678x241270452

Neurovascular coupling (NVC) is the perturbation of cerebral blood flow (CBF) to meet varying metabolic demands induced by various levels of neural activity. NVC may be assessed by Transcranial Doppler ultrasonography (TCD), using task activation pro... Read More about Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement.