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Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials (2023)
Journal Article
Rahman, R., Janowski, M., Killick-Cole, C. L., Singleton, W. G. B., Campbell, E., Walczak, P., …Walker, D. A. (2023). Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials. Cancers, 15(3), Article 857. https://doi.org/10.3390/cancers15030857

Brain and spinal tumors affect 1 in 1000 people by 25 years of age, and have diverse histological, biological, anatomical and dissemination characteristics. A mortality of 30–40% means the majority are cured, although two-thirds have life-long disabi... Read More about Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials.

Fourth Report on Chicken Genes and Chromosomes 2022 (2023)
Journal Article
Smith, J., Alfieri, J. M., Anthony, N., Arensburger, P., Athrey, G. N., Balacco, J., Balic, A., Bardou, P., Barela, P., Bigot, Y., Blackmon, H., Borodin, P. M., Carroll, R., Casono, M. C., Charles, M., Cheng, H., Chiodi, M., Cigan, L., Coghill, L. M., Crooijmans, R., …Zhou, H. (2023). Fourth Report on Chicken Genes and Chromosomes 2022. Cytogenetic and Genome Research, 162(8-9), 405–528. https://doi.org/10.1159/000529376

The chicken continues to hold its position as a leading model organism within many areas of research, as well as being a major source of protein for human consumption. The First Report on Chicken Genes and Chromosomes [Schmid et al., 2000], which was... Read More about Fourth Report on Chicken Genes and Chromosomes 2022.

Exploring the microstructure of hydrated collagen hydrogels under scanning electron microscopy (2023)
Journal Article
Merryweather, D. J., Weston, N., Roe, J., Parmenter, C., Lewis, M. P., & Roach, P. (2023). Exploring the microstructure of hydrated collagen hydrogels under scanning electron microscopy. Journal of Microscopy, 290(1), 40-52. https://doi.org/10.1111/jmi.13174

Collagen hydrogels are a rapidly expanding platform in bioengineering and soft materials engineering for novel applications focused on medical therapeutics, medical devices and biosensors. Observations linking microstructure to material properties an... Read More about Exploring the microstructure of hydrated collagen hydrogels under scanning electron microscopy.

Modelling the influence of mechanical-ecohydrological feedback on the nonlinear dynamics of peatlands (2023)
Journal Article
Mahdiyasa, A. W., Large, D. J., Muljadi, B. P., & Icardi, M. (2023). Modelling the influence of mechanical-ecohydrological feedback on the nonlinear dynamics of peatlands. Ecological Modelling, 478, Article 110299. https://doi.org/10.1016/j.ecolmodel.2023.110299

Peatlands are complex systems that exhibit nonlinear dynamics due to internal and external feedback mechanisms. However, the feedback of vegetation on peat volume changes that potentially affect peatland dynamics is not well understood. Here, we anal... Read More about Modelling the influence of mechanical-ecohydrological feedback on the nonlinear dynamics of peatlands.

Revisiting primary endocrine therapy versus surgery in older women with breast cancer: meta-analysis (2023)
Journal Article
Chan, K. S., Chong, M. T. H., Chia, C. L. K., & Cheung, K. L. (2023). Revisiting primary endocrine therapy versus surgery in older women with breast cancer: meta-analysis. British Journal of Surgery, 110(4), 420-431. https://doi.org/10.1093/bjs/znac435

Background Old age is associated with increased co-morbidities, resulting in reduced life expectancy. Primary endocrine therapy is an alternative to primary surgical therapy for patients with breast cancer and increased co-morbidities. The aim was to... Read More about Revisiting primary endocrine therapy versus surgery in older women with breast cancer: meta-analysis.

The incidence of Kawasaki disease using hospital admissions data for England 2006-2021 (2023)
Journal Article
Odingo, M., Rutter, M., Bowley, J., Peach, E. J., Lanyon, P. C., Grainge, M. J., …Pearce, F. A. (2023). The incidence of Kawasaki disease using hospital admissions data for England 2006-2021. Rheumatology, 62(9), 3117–3125. https://doi.org/10.1093/rheumatology/kead051

Objective: To describe the incidence of Kawasaki Disease (kDa) between 2006 and 2021 in England. Methods: We identified all cases in hospital episode statistics with an ICD-10 diagnostic code M303 (for kDa) between 1 April 2006 and 31 March 2021. We... Read More about The incidence of Kawasaki disease using hospital admissions data for England 2006-2021.

The Association Between Medication Use in Older Women with Early-Stage Operable Primary Breast Cancer and Decision Regarding Primary Treatment (2023)
Journal Article
Tse, N., Parks, R. M., Holmes, H. M., & Cheung, K. L. (2023). The Association Between Medication Use in Older Women with Early-Stage Operable Primary Breast Cancer and Decision Regarding Primary Treatment. Oncologist, 28(3), e128-e135. https://doi.org/10.1093/oncolo/oyac278

Background Polypharmacy is one factor contributing to increased mortality, hospitalization, and adverse drug reactions in older adults. The aim of this study was to measure the prevalence of polypharmacy in a cohort of older women with early-stage op... Read More about The Association Between Medication Use in Older Women with Early-Stage Operable Primary Breast Cancer and Decision Regarding Primary Treatment.

Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners (2023)
Journal Article
Chattopadhyay, K., Kapoor, N., Heinrich, M., Mitra, A., Mittal, M., Lewis, S. A., …Leonardi-Bee, J. (2023). Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners. Frontiers in Medicine, 10, Article 1043715. https://doi.org/10.3389/fmed.2023.1043715

Background: Type 2 diabetes mellitus (T2DM), a common chronic health condition, has major health and socioeconomic consequences. In the Indian subcontinent, it is a health condition for which individuals commonly consult Ayurvedic (traditional medica... Read More about Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners.

Manufacturing Relocation Ambiguity Model: A Prerequisite for Knowledge Management (2023)
Journal Article
Fjellström, D., Hilletofth, P., Fang, T., Kumar, V., Kumar, A., & Hua Tan, K. (2023). Manufacturing Relocation Ambiguity Model: A Prerequisite for Knowledge Management. British Journal of Management, 34(3), 1100-1116. https://doi.org/10.1111/1467-8551.12710

Knowledge management and manufacturing relocation have been treated as independent spheres. However, for a relocation to be fruitful, knowledge management needs to be incorporated. The purpose of this research is to shed light on the lack of knowledg... Read More about Manufacturing Relocation Ambiguity Model: A Prerequisite for Knowledge Management.

Social capital, environmental justice and carcinogenic waste releases: US county-level evidence, 1998–2019 (2023)
Journal Article
Ataullah, A., Coleman, S., Le, H., & Wang, Z. (2023). Social capital, environmental justice and carcinogenic waste releases: US county-level evidence, 1998–2019. Regional Studies, 57(11), 2220-2237. https://doi.org/10.1080/00343404.2022.2159023

We examine the role of social capital in explaining the highly unequal regional distribution of firms’ carcinogenic releases. Our model predicts that social capital, by enabling information-sharing and coordination among community members, decreases... Read More about Social capital, environmental justice and carcinogenic waste releases: US county-level evidence, 1998–2019.

Reflexive governance architectures: Considering the ethical implications of autonomous technology adoption in food supply chains (2023)
Journal Article
Manning, L., Brewer, S., Craigon, P. J., Frey, J., Gutierrez, A., Jacobs, N., …Pearson, S. (2023). Reflexive governance architectures: Considering the ethical implications of autonomous technology adoption in food supply chains. Trends in Food Science and Technology, 133, 114-126. https://doi.org/10.1016/j.tifs.2023.01.015

Background: The application of autonomous technology in food supply chains gives rise to a number of ethical considerations associated with the interaction between human and technology, human-technology-plant and human-technology-animal. These consid... Read More about Reflexive governance architectures: Considering the ethical implications of autonomous technology adoption in food supply chains.

The first year in formal schooling improves working memory and academic abilities (2023)
Journal Article
Davidson, C., Shing, Y. L., McKay, C., Rafetseder, E., & Wijeakumar, S. (2023). The first year in formal schooling improves working memory and academic abilities. Developmental Cognitive Neuroscience, 60, Article 101205. https://doi.org/10.1016/j.dcn.2023.101205

Neurocognition and academic abilities during the period of 4 and 7 years of age are impacted by both the transition from kindergarten to primary school and age-related developmental processes. Here, we used a school cut-off design to tease apart the... Read More about The first year in formal schooling improves working memory and academic abilities.

Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial (2023)
Journal Article
Morriss, R., Patel, S., Boutry, C., Patel, P., Guo, B., Briley, P. M., …Kai, J. (2023). Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial. Lancet Psychiatry, 10(3), 172-183. https://doi.org/10.1016/S2215-0366%2823%2900007-X

Background: Randomised sham-controlled trials of cranial electrostimulation with the Alpha-Stim Anxiety Insomnia and Depression (AID) device have reported improved anxiety and depression symptoms; however, no adequately powered sham-controlled trials... Read More about Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial.

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline (2023)
Journal Article
Thomas, E. O., Manara, A., Dineen, R. A., Mortimer, A., Aziz, O., Dean, P., …Gardiner, D. (2023). The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline. Anaesthesia, 78(3), 330-336. https://doi.org/10.1111/anae.15950

This multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurolog... Read More about The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline.

Anticipating Sino-UK fintech networks and the changing geographies of money as infrastructure (2023)
Journal Article
Hall, S. (2023). Anticipating Sino-UK fintech networks and the changing geographies of money as infrastructure. Environment and Planning A, 55(4), 931-948. https://doi.org/10.1177/0308518X221140413

This paper examines Sino-UK financial relations in the fintech sector. Through an empirical focus on fintech payments systems, the analysis locates fintech within broader research on the internationalisation of Chinese finance. Conceptually, the pape... Read More about Anticipating Sino-UK fintech networks and the changing geographies of money as infrastructure.

Sustainability of Bioenergy – Mapping the Risks & Benefits to Inform Future Bioenergy Systems (2023)
Preprint / Working Paper
James Welfle, A., Almena, A., Naveed Arshad, M., William Banks, S., Butnar, I., Jane Chong, K., Cooper, S. J., Daly, H., Garcia Freites, S., Güleç, F., Hardacre, C., Holland, R., Lan, L., Siah Lee, C., Robertson, P., Rowe, R., Shepherd, A., Skillen, N., Tedesco, S., Thornley, P., …Roeder, M. Sustainability of Bioenergy – Mapping the Risks & Benefits to Inform Future Bioenergy Systems

Bioenergy is widely included in energy strategies for its GHG mitigation potential. Bioenergy technologies will likely have to be deployed at scale to meet decarbonisation targets, and consequently biomass will have to be increasingly grown/mobilised... Read More about Sustainability of Bioenergy – Mapping the Risks & Benefits to Inform Future Bioenergy Systems.

Oral lipid-based formulations alter delivery of cannabidiol to different anatomical regions in the brain (2023)
Journal Article
Brookes, A., Jewell, A., Feng, W., Bradshaw, T. D., Butler, J., & Gershkovich, P. (2023). Oral lipid-based formulations alter delivery of cannabidiol to different anatomical regions in the brain. International Journal of Pharmaceutics, 635, Article 122651. https://doi.org/10.1016/j.ijpharm.2023.122651

Delivery to the brain is a challenging task due to its protection by the blood–brain barrier (BBB). Lipids and fatty acids are reported to affect the permeability of the BBB, although this has not been reported following oral administration. Cannabid... Read More about Oral lipid-based formulations alter delivery of cannabidiol to different anatomical regions in the brain.

Building Resilient Crop Production Systems for Drought-Prone Areas—A Case for Bambara Groundnut (Vigna subterranea L. Verdc) and Groundnut (Arachis hypogaea L.) (2023)
Journal Article
Kundy, A. C., Mayes, S., Msanya, B., Ndakidemi, P., & Massawe, F. (2023). Building Resilient Crop Production Systems for Drought-Prone Areas—A Case for Bambara Groundnut (Vigna subterranea L. Verdc) and Groundnut (Arachis hypogaea L.). Agronomy, 13(2), Article 383. https://doi.org/10.3390/agronomy13020383

Drought is a major crop production constraint worldwide. Some legume crops are known for their ability to resist water deficit stress. This study evaluated the responses of bambara groundnut (Vigna subterranea (L.) Verdc) and groundnut (Arachis hypog... Read More about Building Resilient Crop Production Systems for Drought-Prone Areas—A Case for Bambara Groundnut (Vigna subterranea L. Verdc) and Groundnut (Arachis hypogaea L.).

The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis (2023)
Journal Article
Sahota, G. S., Fisher, V., Patel, B., JuJ, K., & Taggar, J. S. (2023). The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis. Medical Teacher, 45(9), 997-1004. https://doi.org/10.1080/0142159x.2023.2168183

Introduction
Situational judgement tests (SJTs) are a recognised assessment method for admission into medical school, selection into postgraduate training programs, and postgraduate competency assessment. More recently, however, SJTs have been used... Read More about The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis.