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Making Landscape Decisions to Meet Net Zero Carbon: Pathways that consider ethics, socio-ecological diversity, and landscape functions. (2022)
Report
Cole, B., Saratsi, E., Earnshaw, K., Wilcock, S., Gardner, E., Bradley, A., …Bezant, J. (2022). Making Landscape Decisions to Meet Net Zero Carbon: Pathways that consider ethics, socio-ecological diversity, and landscape functions. University of Leicester: NERC Landscape Decisions

Landscapes are an integral part of the net-zero challenge; not only are they carbon
stores but they constitute the environments upon which humans develop their livelihoods,
interact and shape their cultures.
This report focuses on three key landsc... Read More about Making Landscape Decisions to Meet Net Zero Carbon: Pathways that consider ethics, socio-ecological diversity, and landscape functions..

Performance Analysis of Zero-Difference GPS L1/L2/L5 and Galileo E1/E5a/E5b/E6 Point Positioning Using CNES Uncombined Bias Products (2022)
Journal Article
Zhao, L., Blunt, P., & Yang, L. (2022). Performance Analysis of Zero-Difference GPS L1/L2/L5 and Galileo E1/E5a/E5b/E6 Point Positioning Using CNES Uncombined Bias Products. Remote Sensing, 14(3), Article 650. https://doi.org/10.3390/rs14030650

The modernization of Global Navigation Satellite System (GNSS) including the transmission of signals on multiple frequencies has greatly promoted the development of the popular PPP (Precise Point Positioning) technique. A key issue of multi-frequency... Read More about Performance Analysis of Zero-Difference GPS L1/L2/L5 and Galileo E1/E5a/E5b/E6 Point Positioning Using CNES Uncombined Bias Products.

Challenges in Geriatric Oncology—A Surgeon’s Perspective (2022)
Journal Article
Parks, R., & Cheung, K. L. (2022). Challenges in Geriatric Oncology—A Surgeon’s Perspective. Current Oncology, 29(2), 659-674. https://doi.org/10.3390/curroncol29020058

As our global population ages, we will see more cancer diagnoses in older adults. Surgery is an important treatment modality for solid tumours, forming the majority of all cancers. However, the management of older adults with cancer can be more compl... Read More about Challenges in Geriatric Oncology—A Surgeon’s Perspective.

Silicic Acid Cycling in the Bering Sea During the Mid-Pleistocene Transition (2022)
Journal Article
Worne, S., Swann, G. E., Kender, S., Lacey, J. H., & Leng, M. J. (2022). Silicic Acid Cycling in the Bering Sea During the Mid-Pleistocene Transition. Paleoceanography and Paleoclimatology, 37(2), Article e2021PA004284. https://doi.org/10.1029/2021PA004284

The rate of deep-ocean carbon burial is considered important for modulating glacial-interglacial atmospheric CO2 concentrations and global climate during the Quaternary. It has been suggested that glacial iron fertilization and increased efficiency o... Read More about Silicic Acid Cycling in the Bering Sea During the Mid-Pleistocene Transition.

Characterization of potential nanoporous sodium titanate film formation on Ti6Al4V and TiO2 microspherical substrates via wet-chemical alkaline conversion (2022)
Journal Article
Wadge, M. D., Carrington, M. J., Constantin, H., Orange, K., Greaves, J., Islam, M. T., …Grant, D. M. (2022). Characterization of potential nanoporous sodium titanate film formation on Ti6Al4V and TiO2 microspherical substrates via wet-chemical alkaline conversion. Materials Characterization, 185, Article 111760. https://doi.org/10.1016/j.matchar.2022.111760

The authors present novel insights into the formation of nanoporous, wet-chemically produced sodium titanate films onto microspherical substrates of varying composition. Microspheres of Ti6Al4V (atomised; ca. 20–50 μm), which were utilised due to the... Read More about Characterization of potential nanoporous sodium titanate film formation on Ti6Al4V and TiO2 microspherical substrates via wet-chemical alkaline conversion.

Government R&D support and firms’ access to external financing: funding effects, certification effects, or both? (2022)
Journal Article
Guo, D., Guo, Y., & Jiang, K. (2022). Government R&D support and firms’ access to external financing: funding effects, certification effects, or both?. Technovation, 115, Article 102469. https://doi.org/10.1016/j.technovation.2022.102469

We examine the effects of government R&D support on a firm's access to external financing, focusing on the mechanisms through which the impacts are achieved. Based on a panel dataset of Chinese manufacturing firms, we compare firms backed by governme... Read More about Government R&D support and firms’ access to external financing: funding effects, certification effects, or both?.

Impact of receiving recorded mental health recovery narratives on quality of life in people experiencing non-psychosis mental health problems (NEON-O Trial): updated randomised controlled trial protocol (2022)
Journal Article
Rennick-Egglestone, S., Elliott, R., Newby, C., Robinson, C., & Slade, M. (2022). Impact of receiving recorded mental health recovery narratives on quality of life in people experiencing non-psychosis mental health problems (NEON-O Trial): updated randomised controlled trial protocol. Trials, 23, Article 90. https://doi.org/10.1186/s13063-022-06027-z

Background: Mental health recovery narratives are first-person lived experience accounts of recovery from mental health problems, which refer to events or actions over a period of time, and which include elements of adversity or struggle, and also se... Read More about Impact of receiving recorded mental health recovery narratives on quality of life in people experiencing non-psychosis mental health problems (NEON-O Trial): updated randomised controlled trial protocol.

Genetic Associations and Architecture of Asthma-COPD Overlap (2022)
Journal Article
John, C., Guyatt, A. L., Shrine, N., Packer, R., Olafsdottir, T. A., Liu, J., …Tobin, M. D. (2022). Genetic Associations and Architecture of Asthma-COPD Overlap. Chest, 161(5), 1155-1166. https://doi.org/10.1016/j.chest.2021.12.674

Background
Some people have characteristics of both asthma and COPD (asthma-COPD overlap), and evidence suggests they experience worse outcomes than those with either condition alone.
Research Question
What is the genetic architecture of asthma-CO... Read More about Genetic Associations and Architecture of Asthma-COPD Overlap.

The effectiveness of psychological interventions on mental health and quality of life in people living with type 1 diabetes: a systematic review and meta-analysis (2022)
Journal Article
Efthymiadis, A., Bourlaki, M., & Bastounis, A. (2022). The effectiveness of psychological interventions on mental health and quality of life in people living with type 1 diabetes: a systematic review and meta-analysis. Diabetology International, https://doi.org/10.1007/s13340-021-00564-9

Background: Living with type 1 diabetes can be associated with significant psychological morbidity, poor glycaemic control, and increased risk for microvascular complications. This systematic review sought to investigate the effects of psychological... Read More about The effectiveness of psychological interventions on mental health and quality of life in people living with type 1 diabetes: a systematic review and meta-analysis.

Immerse Yourself in ASPIRE - Adding Persuasive Technology Methodology to the ASPIRE Framework (2022)
Presentation / Conference Contribution
Taylor, M., Wharrad, H., & Konstantinidis, S. (2021, September). Immerse Yourself in ASPIRE - Adding Persuasive Technology Methodology to the ASPIRE Framework. Presented at 24th International Conference on Interactive Collaborative Learning (ICL2021), Dresden, Germany

With their ability to captivate learners and simulate real world scenarios it is little wonder that healthcare education is experiencing rapid growth in the use of Immersive technologies such as Augmented Reality (AR), Virtual Reality (VR) and Extend... Read More about Immerse Yourself in ASPIRE - Adding Persuasive Technology Methodology to the ASPIRE Framework.

Charting galactic accelerations - II: How to ‘learn’ accelerations in the solar neighbourhood (2022)
Journal Article
Naik, A. P., An, J., Burrage, C., & Evans, N. W. (2022). Charting galactic accelerations - II: How to ‘learn’ accelerations in the solar neighbourhood. Monthly Notices of the Royal Astronomical Society, 511(2), 1609-1621. https://doi.org/10.1093/mnras/stac153

Gravitational acceleration fields can be deduced from the collisionless Boltzmann equation, once the distribution function is known. This can be constructed via the method of normalizing flows from data sets of the positions and velocities of stars.... Read More about Charting galactic accelerations - II: How to ‘learn’ accelerations in the solar neighbourhood.

The bright extragalactic ALMA redshift survey (BEARS) I: redshifts of bright gravitationally lensed galaxies from the Herschel ATLAS (2022)
Journal Article
Urquhart, S. A., Bendo, G. J., Serjeant, S., Bakx, T., Hagimoto, M., Cox, P., …Young, A. J. (2022). The bright extragalactic ALMA redshift survey (BEARS) I: redshifts of bright gravitationally lensed galaxies from the Herschel ATLAS. Monthly Notices of the Royal Astronomical Society, 511(2), 3017–3033. https://doi.org/10.1093/mnras/stac150

We present spectroscopic measurements for 71 galaxies associated with 62 of the brightest high-redshift submillimetre sources from the Southern fields of the Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS), while targeting 85 sources whi... Read More about The bright extragalactic ALMA redshift survey (BEARS) I: redshifts of bright gravitationally lensed galaxies from the Herschel ATLAS.

Health Technology Adoption in Liver Disease: Innovative Use of Data Science Solutions for Early Disease Detection (2022)
Journal Article
Bennett, L., Purssell, H., Street, O., Piper Hanley, K., Morling, J. R., Hanley, N. A., …ID-LIVER Consortium. (2022). Health Technology Adoption in Liver Disease: Innovative Use of Data Science Solutions for Early Disease Detection. Frontiers in Digital Health, 4, Article 737729. https://doi.org/10.3389/fdgth.2022.737729

Chronic liver disease (CLD) is an ignored epidemic. Premature mortality is considerable and in the United Kingdom (UK) liver disease is in the top three for inequitable healthcare alongside heart and respiratory disease. Fifty percentage of patients... Read More about Health Technology Adoption in Liver Disease: Innovative Use of Data Science Solutions for Early Disease Detection.

Historiarum libri quinque: Hegesippus between Josephus and Sallust (2022)
Journal Article
Woudhuysen, G., & Stover, J. (2022). Historiarum libri quinque: Hegesippus between Josephus and Sallust. Histos, 16, 1-27

This article examines the influence of Sallust on Hegesippus, the fourth-century historian and adaptor of Josephus (commonly referred to as pseudo-Hegesippus). Analysis of the structure of his work reveals that Hegesippus strove to write in five book... Read More about Historiarum libri quinque: Hegesippus between Josephus and Sallust.

Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021 (2022)
Journal Article
Abhishek, A., Tata, L. J., Mamas, M., & Avery, A. J. (2022). Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021. Annals of the Rheumatic Diseases, 81(6), 898-899. https://doi.org/10.1136/annrheumdis-2021-221989

Design and Performance of L-CaPaMan2 (2022)
Journal Article
Titov, A., Russo, M., & Ceccarelli, M. (2022). Design and Performance of L-CaPaMan2. Applied Sciences, 12(3), Article 1380. https://doi.org/10.3390/app12031380

The improved solution of L‐CaPaMan design is elaborated with solutions for low‐cost lightweight features. A new prototype is presented as a result of design improvements by using market components and 3D printing manufacturing. The new prototype as L... Read More about Design and Performance of L-CaPaMan2.

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease (2022)
Preprint / Working Paper
Holstege, H., Hulsman, M., Charbonnier, C., Grenier-Boley, B., Quenez, O., Grozeva, D., …Lambert, J.-C. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease

The genetic component of Alzheimer’s disease (AD) has been mainly assessed using Genome Wide Association Studies (GWAS), which do not capture the risk contributed by rare variants. Here, we compared the gene-based burden of rare damaging variants in... Read More about Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease.

Development of a Gene-Activated Scaffold Incorporating Multifunctional Cell-Penetrating Peptides for pSDF-1α Delivery for Enhanced Angiogenesis in Tissue Engineering Applications (2022)
Journal Article
Power, R. N., Cavanagh, B. L., Dixon, J. E., Curtin, C. M., & O’Brien, F. J. (2022). Development of a Gene-Activated Scaffold Incorporating Multifunctional Cell-Penetrating Peptides for pSDF-1α Delivery for Enhanced Angiogenesis in Tissue Engineering Applications. International Journal of Molecular Sciences, 23(3), Article 1460. https://doi.org/10.3390/ijms23031460

Non-viral gene delivery has become a popular approach in tissue engineering, as it permits the transient delivery of a therapeutic gene, in order to stimulate tissue repair. However, the efficacy of non-viral delivery vectors remains an issue. Our la... Read More about Development of a Gene-Activated Scaffold Incorporating Multifunctional Cell-Penetrating Peptides for pSDF-1α Delivery for Enhanced Angiogenesis in Tissue Engineering Applications.