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Passive control of temperature distribution in cancerous tissue during photothermal therapy using optical phase change nanomaterials (2020)
Journal Article
Ren, Y., Chen, Q., Li, H., Qi, H., & Yan, Y. (2021). Passive control of temperature distribution in cancerous tissue during photothermal therapy using optical phase change nanomaterials. International Journal of Thermal Sciences, 161, Article 106754. https://doi.org/10.1016/j.ijthermalsci.2020.106754

Thermal therapy is a very promising alternative treatment for benign tumor, in which the temperature control is a key issue to avoid unwanted thermal damage of healthy tissue. However, the active temperature control methods usually require the assist... Read More about Passive control of temperature distribution in cancerous tissue during photothermal therapy using optical phase change nanomaterials.

Identifying, managing and supporting patients with a rare disease (2020)
Journal Article
Evans, W., McKay, L., & Qureshi, N. (2021). Identifying, managing and supporting patients with a rare disease. InnovAiT, 14(2), 92-99. https://doi.org/10.1177/1755738020974411

Rare diseases (RDs) are defined as diseases that affect less than 1 in 2000 people, 71.9% are genetic and 69.9% have symptom onset in childhood. There are an estimated 8000 rare diseases, and although individually rare, collectively they are common,... Read More about Identifying, managing and supporting patients with a rare disease.

Understanding farmers' naturalistic decision making around prophylactic antibiotic use in lambs using a grounded theory and natural language processing approach (2020)
Journal Article
Doidge, C., Ferguson, E., Lovatt, F., & Kaler, J. (2021). Understanding farmers' naturalistic decision making around prophylactic antibiotic use in lambs using a grounded theory and natural language processing approach. Preventive Veterinary Medicine, 186, Article 105226. https://doi.org/10.1016/j.prevetmed.2020.105226

The routine use of antibiotics for prevention of disease in neonatal lambs has been highlighted as inappropriate, yet research suggests that many farmers in the UK still carry out this practice. The aim of the study was to understand farmers' natural... Read More about Understanding farmers' naturalistic decision making around prophylactic antibiotic use in lambs using a grounded theory and natural language processing approach.

PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages (2020)
Journal Article
Mahri, S., Hardy, E., Wilms, T., De Keersmaecker, H., Braeckmans, K., De Smedt, S., Bosquillon, C., & Vanbever, R. (2021). PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages. International Journal of Pharmaceutics, 593, Article 120107. https://doi.org/10.1016/j.ijpharm.2020.120107

Conjugation to high molecular weight (MW ≥ 20 kDa) polyethylene glycol (PEG) was previously shown to largely prolong the lung residence time of recombinant human deoxyribonuclease I (rhDNase) and improve its therapeutic efficacy following pulmonary d... Read More about PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages.

Porous ceramics: Light in weight but heavy in energy and environment technologies (2020)
Journal Article
Chen, Y., Wang, N., Ola, O., Xia, Y., & Zhu, Y. (2021). Porous ceramics: Light in weight but heavy in energy and environment technologies. Materials Science and Engineering: R: Reports, 143, Article 100589. https://doi.org/10.1016/j.mser.2020.100589

Benefitting from the combined properties of intrinsic ceramic materials and advanced porous configuration, lightweight porous ceramics with porosity ranging from 2.3 to 99% and pore size distribution within 3 nm - 3 mm exhibit low density, large spec... Read More about Porous ceramics: Light in weight but heavy in energy and environment technologies.

Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China (2020)
Journal Article
Cong, W., Elsheikha, H. M., Li, M.-Y., Ma, J.-Y., Zou, Y., & Jiang, Z.-Y. (2021). Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China. Acta Tropica, 214, Article 105779. https://doi.org/10.1016/j.actatropica.2020.105779

Increasing evidence exisits for the role that shellfish play in the epidemiology of Toxoplasma gondii in marine environment. However, limited information is available on the level of T. gondii infection in wild marine snails, which can play a role in... Read More about Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China.

A paradox in bacterial pathogenesis: Activation of the local macrophage inflammasome is required for virulence of streptococcus uberis (2020)
Journal Article
Archer, N., Egan, S. A., Coffey, T. J., Emes, R. D., Addis, M. F., Ward, P. N., Blanchard, A. M., & Leigh, J. A. (2020). A paradox in bacterial pathogenesis: Activation of the local macrophage inflammasome is required for virulence of streptococcus uberis. Pathogens, 9(12), 1-23. https://doi.org/10.3390/pathogens9120997

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Streptococcus uberis is a common cause of intramammary infection and mastitis in dairy cattle. Unlike other mammary pathogens, S. uberis evades detection by mammary epithelial cells, and the h... Read More about A paradox in bacterial pathogenesis: Activation of the local macrophage inflammasome is required for virulence of streptococcus uberis.

Experimental investigation into the integration of solid desiccant packed beds with oscillating heat pipes for energy efficient isothermal adsorption processes (2020)
Journal Article
Yeboah, S. K., & Darkwa, J. (2021). Experimental investigation into the integration of solid desiccant packed beds with oscillating heat pipes for energy efficient isothermal adsorption processes. Thermal Science and Engineering Progress, 21, Article 100791. https://doi.org/10.1016/j.tsep.2020.100791

The heat of adsorption released during physical adsorption of water vapour on solid desiccants increases its surface vapour pressure consequently decreasing its adsorption capacity. In packed beds, this raises the bed temperature subsequently increas... Read More about Experimental investigation into the integration of solid desiccant packed beds with oscillating heat pipes for energy efficient isothermal adsorption processes.

High rates of biodeposition and N-excretion indicate strong functional effects of mussels (Bivalvia: Unionida) in certain anthropogenic tropical freshwater habitats (2020)
Journal Article
Zieritz, A., Ning, C. W., Mcgowan, S., & Gibbins, C. (2021). High rates of biodeposition and N-excretion indicate strong functional effects of mussels (Bivalvia: Unionida) in certain anthropogenic tropical freshwater habitats. Hydrobiologia, 848(12-13), 3153-3166. https://doi.org/10.1007/s10750-020-04464-y

The functional roles of freshwater mussels (Unionida) in tropical systems are poorly understood. We quantified the effects of mussel filtration, excretion and deposition in three anthropogenic tropical systems, i.e. a man-made lake, abandoned mining... Read More about High rates of biodeposition and N-excretion indicate strong functional effects of mussels (Bivalvia: Unionida) in certain anthropogenic tropical freshwater habitats.

Iterative Run-to-Run Learning Model to Derive Continuous Brachial Pressure Estimates from Arterial and Venous Lines During Dialysis Treatment (2020)
Journal Article
Stewart, J., Stewart, P., Walker, T., Viramontes Horner, D., Lucas, B., White, K., Taal, M. W., Selby, N. M., & Morris, M. (2021). Iterative Run-to-Run Learning Model to Derive Continuous Brachial Pressure Estimates from Arterial and Venous Lines During Dialysis Treatment. Biomedical Signal Processing and Control, 65, Article 102346. https://doi.org/10.1016/j.bspc.2020.102346

Objective: Non-invasive continuous blood pressure monitoring is not yet part of routine practice in renal dialysis units but could be a valuable tool in the detection and prevention of significant variations in patient blood pressure during treatment... Read More about Iterative Run-to-Run Learning Model to Derive Continuous Brachial Pressure Estimates from Arterial and Venous Lines During Dialysis Treatment.

Outpatient physiotherapy versus home-based rehabilitation for patients at risk of poor outcomes after knee arthroplasty: CORKA RCT (2020)
Journal Article
Lamb, S. E., Schussel, M. M., Barker, K. L., Room, J., Knight, R., Dutton, S. J., Toye, F., Leal, J., Kent, S., Kenealy, N., Maia Schussel, M., Collins, G., Beard, D. J., Price, A., Underwood, M., Drummond, A., Cook, E., & Lamb, S. E. (2020). Outpatient physiotherapy versus home-based rehabilitation for patients at risk of poor outcomes after knee arthroplasty: CORKA RCT. Health Technology Assessment, 24(65), 1-115. https://doi.org/10.3310/hta24650

Background: Over 100,000 primary knee arthroplasty operations are undertaken annually in the UK. Around 15–30% of patients do not report a good outcome. Better rehabilitation strategies may improve patient-reported outcomes. Objectives: To compare th... Read More about Outpatient physiotherapy versus home-based rehabilitation for patients at risk of poor outcomes after knee arthroplasty: CORKA RCT.

Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety (2020)
Journal Article
Thurley, P., Bowker, R., Bhatti, I., Skelly, R., Law, R., Salaman, R., Young, B., & Fogarty, A. (2020). Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety. BMJ Open Quality, 9(4), Article e000900. https://doi.org/10.1136/bmjoq-2019-000900

Background Over recent decades, CT scans have become routinely available and are used in both acute medical and outpatient environments. However, there is a small increase in the risk of adverse consequences, including an increase in the risk of both... Read More about Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety.

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells (2020)
Journal Article
Stoddart, L. A., Kindon, N. D., Otun, O., Harwood, C. R., Patera, F., Veprintsev, D. B., Woolard, J., Briddon, S. J., Franks, H. A., Hill, S. J., & Kellam, B. (2020). Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells. Communications Biology, 3(1), Article 722. https://doi.org/10.1038/s42003-020-01451-w

© 2020, The Author(s). To study the localisation of G protein-coupled receptors (GPCR) in their native cellular environment requires their visualisation through fluorescent labelling. To overcome the requirement for genetic modification of the recept... Read More about Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells.

Deliberate Practice in Simulation-Based Surgical Skills Training: A Scoping Review (2020)
Journal Article
Higgins, M., Madan, C. R., & Patel, R. (2021). Deliberate Practice in Simulation-Based Surgical Skills Training: A Scoping Review. Journal of Surgical Education, 78(4), 1328-1339. https://doi.org/10.1016/j.jsurg.2020.11.008

BACKGROUND: In recent years there has been a shift from traditional Halstedian methods toward more simulation-based medical education (SBME) for developing surgical skills. Questions remain about the role and value of SBME, although feedback and enga... Read More about Deliberate Practice in Simulation-Based Surgical Skills Training: A Scoping Review.

USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER (2020)
Journal Article
Jacinto, A. F., Achterberg, W., Wachholz, P. A., Dening, T., Dening, K. H., Devi, R., Oliveira, D., Everink, I., Azevedo, P. S., Villas Boas, P. J., Hinsliff-Smith, K., Hoedl, M., Schols, J. M., Shepherd, V., Gratao, A., Watanabe, H. A., Zazzetta, M. S., Goodman, C., Spilsby, K., & Gordon, A. (2020). USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER. Journal of Nursing Home Research, 6(109-113), https://doi.org/10.14283/jnhrs.2020.28

The Brazilian care home sector is underdeveloped, and the limited available evidence suggests that care quality falls below international standards. Development of the Brazilian care home sector could be associated with better outcomes for those rece... Read More about USING INTERNATIONAL COLLABORATIONS TO SHAPE RESEARCH AND INNOVATION INTO CARE HOMES IN BRAZIL: A WHITE PAPER.

Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans (2020)
Journal Article
Wilson, C. A., Berger, J. I., De Boer, J., Sereda, M., Hall, D. A., & Wallace, M. N. (2020). Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans. Acta Scientific Otolaryngology, 2(12), 40-52

A widely used method for detecting tinnitus in rodents is the gap pre-pulse inhibition of the acoustic startle (GPIAS). One variant uses the Preyer reflex to assess the startle response and a component of this can be measured as a small muscle pote... Read More about Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans.

Temperature effect on the material removal mechanism of soft-brittle crystals at nano/micron scale (2020)
Journal Article
Liu, Q., Liao, Z., & Axinte, D. (2020). Temperature effect on the material removal mechanism of soft-brittle crystals at nano/micron scale. International Journal of Machine Tools and Manufacture, 159(Part B), Article 103620. https://doi.org/10.1016/j.ijmachtools.2020.103620

© 2020 Elsevier Ltd Soft-brittle crystals, e.g. KH2PO4 (KDP), are difficult-to-cut due to their high brittleness which can easily generate crack during the machining process. The conventional method to machine this kind of material is by inducing duc... Read More about Temperature effect on the material removal mechanism of soft-brittle crystals at nano/micron scale.

Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT (2020)
Journal Article
Batchelor, J. M., Thomas, K. S., Akram, P., Azad, J., Bewley, A., Chalmers, J. R., Cheung, S. T., Duley, L., Eleftheriadou, V., Ellis, R., Ferguson, A., Goulding, J. M., Haines, R. H., Hamad, H., Ingram, J. R., Laguda, B., Leighton, P., Levell, N., Makrygeorgou, A., Meakin, G. D., …Montgomery, A. A. (2020). Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT. Health Technology Assessment, 24(64), 1-164. https://doi.org/10.3310/hta24640

Background: Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo. Objective: To explore the clinical effectiveness and cost-effecti... Read More about Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT.