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Metal–organic frameworks constructed from Group 1 metals (Li, Na) and silicon-centered linkers (2018)
Journal Article
Pugh, D., Ashworth, E., Robertson, K., Delmas, L. C., White, A. J. P., Horton, P. N., …Davies, R. P. (2019). Metal–organic frameworks constructed from Group 1 metals (Li, Na) and silicon-centered linkers. Crystal Growth and Design, 19(1), 487-497. https://doi.org/10.1021/acs.cgd.8b01567

A series of “light metal” metal–organic frameworks containing secondary building units (SBUs) based on Li+ and Na+ cations have been prepared using the silicon-centered linkers MexSi(p-C6H4CO2H)4-x (x = 2, 1, 0). The unipositive charge, small size, a... Read More about Metal–organic frameworks constructed from Group 1 metals (Li, Na) and silicon-centered linkers.

The benefits of international volunteering in a low-resource setting: development of a core outcome set (2018)
Journal Article
Tyler, N., Chatwin, J., Byrne, G., Hart, J., & Byrne-Davis, L. (2018). The benefits of international volunteering in a low-resource setting: development of a core outcome set. Human Resources for Health, 16(1), Article 69. https://doi.org/10.1186/s12960-018-0333-5

Background: Qualitative narrative analysis and case studies form the majority of the current peer-reviewed literature about the benefits of professional volunteering or international placements for healthcare professionals. These often describe gener... Read More about The benefits of international volunteering in a low-resource setting: development of a core outcome set.

Tensions within the Ministry of Provenance: reflections on co-creating a research game together with artists (2018)
Journal Article
Wetzel, R., Bachour, K., & Flintham, M. (2018). Tensions within the Ministry of Provenance: reflections on co-creating a research game together with artists. Simulation and Gaming, 50(3), 329-358. https://doi.org/10.1177/1046878118818867

Background: Research games are challenging to design as they seek to fulfil a research agenda as well as work as a game. We have successfully collaborated with a group of artists in a research game about people’s perception of provenance called The A... Read More about Tensions within the Ministry of Provenance: reflections on co-creating a research game together with artists.

Local asymptotic equivalence of pure states ensembles and quantum Gaussian white noise (2018)
Journal Article
Butucea, C., Guţă, M., & Nussbaum, M. (2018). Local asymptotic equivalence of pure states ensembles and quantum Gaussian white noise. Annals of Statistics, 46(6B), 3676-3706. https://doi.org/10.1214/17-aos1672

Quantum technology is increasingly relying on specialised statistical inference methods for analysing quantum measurement data. This motivates the development of “quantum statistics”, a field that is shaping up at the overlap of quantum physics and “... Read More about Local asymptotic equivalence of pure states ensembles and quantum Gaussian white noise.

Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis (2018)
Journal Article
Otete, H., Fleming, K. M., West, J., & Orton, E. (2019). Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis. Alcohol and Alcoholism, 54(2), 131–138. https://doi.org/10.1093/alcalc/agy085

Aims: This study aimed to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk.

Method: Using linked gene... Read More about Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis.

Testing explosive bubbles with time-varying volatility (2018)
Journal Article
Harvey, D. I., Leybourne, S. J., & Zu, Y. (2019). Testing explosive bubbles with time-varying volatility. Econometric Reviews, 38(10), 1131-1151. https://doi.org/10.1080/07474938.2018.1536099

This paper considers the problem of testing for an explosive bubble in financial data in the presence of time-varying volatility. We propose a weighted least squares-based variant of the Phillips, Wu and Yu (2011) test for explosive autoregressive be... Read More about Testing explosive bubbles with time-varying volatility.

Cell death pathologies: targeting death pathways and the immune system for cancer therapy (2018)
Journal Article
Pentimalli, F., Grelli, S., Di Daniele, N., Melino, G., & Amelio, I. (2019). Cell death pathologies: targeting death pathways and the immune system for cancer therapy. Genes and Immunity, 20(7), 539-554. https://doi.org/10.1038/s41435-018-0052-x

Alterations in the molecular mechanisms of cell death are a common feature of cancer. These alterations enable malignant cells to survive intrinsic death signalling leading to accumulation of genetic aberrations and helping them to cope with adverse... Read More about Cell death pathologies: targeting death pathways and the immune system for cancer therapy.

Temporal relationships between systemic lupus erythematosus and comorbidities (2018)
Journal Article
Kuo, C. F., Chou, I.-J., Rees, F., Grainge, M. J., Lanyon, P., Davenport, G., …Doherty, M. (2019). Temporal relationships between systemic lupus erythematosus and comorbidities. Rheumatology, 58(5), 840-848. https://doi.org/10.1093/rheumatology/key335

© The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. Objective: To examine the burden of comorbidities prior to and after the diagnosis of SLE and its impact on mortality.... Read More about Temporal relationships between systemic lupus erythematosus and comorbidities.

A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare (2018)
Journal Article
Liu, L., Hao, F., Morgan, S. P., Correia, R., Norris, A., & Korposh, S. (2019). A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare. Sensing and Bio-Sensing Research, 22, Article 100254. https://doi.org/10.1016/j.sbsr.2018.100254

A reflection-mode carbon dioxide (CO2) fibre optic sensor (FOS) is developed based on the colorimetric change of pH indicator dye thymol blue. The CO2 sensing film comprises thymol blue and tetramethylammonium hydroxide in the form of an ion pair dop... Read More about A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare.

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 (2018)
Journal Article
Tzelepis, K., De Braekeleer, E., Aspris, D., Barbieri, I., Vijayabaskar, M. S., Liu, W., …Vassiliou, G. S. (2018). SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature Communications, 9(1), Article 5378. https://doi.org/10.1038/s41467-018-07620-0

We recently identified the splicing kinase gene SRPK1 as a genetic vulnerability of acute myeloid leukemia (AML). Here, we show that genetic or pharmacological inhibition of SRPK1 leads to cell cycle arrest, leukemic cell differentiation and prolonge... Read More about SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.

The mathematical backgrounds of undergraduates from England (2018)
Journal Article
Hodgen, J., Adkins, M., & Tomei, A. (2020). The mathematical backgrounds of undergraduates from England. Teaching Mathematics and its Applications, 39(1), 38–60. https://doi.org/10.1093/teamat/hry017

Participation in any kind of mathematical study during upper secondary education in England is significantly lower than in other educational systems. As a result, many English students enter university at age 18 or 19 having not studied mathematics f... Read More about The mathematical backgrounds of undergraduates from England.

Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1 (2018)
Journal Article
Sanchez, J., e Huma, Z., Lane, J., Liu, X., Bridgford, J. L., Payne, R. J., …Stone, M. J. (2018). Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1. Journal of Biological Chemistry, 294(10), 3464-3475. https://doi.org/10.1074/jbc.ra118.006535

© 2019 Sanchez et al. Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc. Interactions between secreted immune proteins called chemokines and their cognate G protein– coupled receptors regulate the t... Read More about Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1.

Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma (2018)
Journal Article
Burchill, S. A., Ziegler, D. S., Etchevers, H. C., Norris, M. D., Cheng, P. N., McConville, C. M., …Mussai, F. (2019). Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma. Cancer Research, 79(3), 611-624. https://doi.org/10.1158/0008-5472.CAN-18-2139

© 2018 American Association for Cancer Research. Neuroblastoma is the most common childhood solid tumor, yet the prognosis for high-risk disease remains poor. We demonstrate here that arginase 2 (ARG2) drives neuroblastoma cell proliferation via regu... Read More about Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma.

Interventions for treating wrist fractures in children (Review) (2018)
Journal Article
H.G. Handoll, H., Elliott, J., Iheozor‐Ejiofor, Z., Hunter, J., & Karantana, A. (2018). Interventions for treating wrist fractures in children (Review). Cochrane Database of Systematic Reviews, 2018(12), 1-239. https://doi.org/10.1002/14651858.CD012470.pub2

© 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Wrist fractures, involving the distal radius, are the most common fractures in children. Most are buckle fractures, which are stable fractures, unlike greenstick an... Read More about Interventions for treating wrist fractures in children (Review).

In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide (2018)
Journal Article
Temperton, R., Gibson, A., & O'Shea, J. (2018). In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide. Physical Chemistry Chemical Physics, 21(3), 1393-1398. https://doi.org/10.1039/c8cp06912c

Ultra-thin aluminium oxide was grown on a rutile titanium dioxide surface by atomic layer deposition using trimethylaluminium and water precursors. This process, carried out using realistic temperatures and pressures (1 mbar, 450 K), was monitored in... Read More about In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide.

Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum (2018)
Journal Article
Sharma, P., Hartley, C. S., Haque, M., Coffey, T. J., Egan, S. A., & Flynn, R. J. (2018). Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum. Frontiers in Immunology, 9, Article 3011. https://doi.org/10.3389/fimmu.2018.03011

The neonatal period represents a window of susceptibility for ruminants given the abundance of infectious challenges in their environment. Maternal transfer of immunity does not occur in utero but post-parturition, however this does not compensate fo... Read More about Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum.

Closure of the Bering Strait caused Mid-Pleistocene Transition cooling (2018)
Journal Article
Kender, S., Ravelo, A. C., Worne, S., Swann, G. E. A., Leng, M. J., Asahi, H., …Hall, I. R. (2018). Closure of the Bering Strait caused Mid-Pleistocene Transition cooling. Nature Communications, 9(1), Article 5386. https://doi.org/10.1038/s41467-018-07828-0

The Mid-Pleistocene Transition (MPT) is characterised by cooling and lengthening glacial cycles from 600–1200 ka, thought to be driven by reductions in glacial CO2 in particular from ~900 ka onwards. Reduced high latitude upwelling, a process that re... Read More about Closure of the Bering Strait caused Mid-Pleistocene Transition cooling.

Portfolio sales and signaling (2018)
Journal Article
Bougheas, S., & Worrall, T. (2019). Portfolio sales and signaling. Journal of Banking and Finance, 99, 182-191. https://doi.org/10.1016/j.jbankfin.2018.12.008

This paper extends the DeMarzo and Duffie (1999) signaling model from single sales to portfolio sales. It shows that the extended model can account for retention of low quality assets and help explain why retained assets may be of varying quality.