Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence
(2018)
Journal Article
Evans, T., D. Johnson, A., & Loose, M. (in press). Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence. Scientific Reports, 8(1), Article 618. https://doi.org/10.1038/s41598-017-19128-6
Large repeat rich genomes present challenges for assembly using short read technologies. The 32 Gb axolotl genome is estimated to contain ~19 Gb of repetitive DNA making an assembly from short reads alone effectively impossible. Indeed, this model sp... Read More about Virtual genome walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence.