All Outputs (2792)

Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases (2014)
Journal Article
Jenner, M., Afonso, J. P., Bailey, H. R., Frank, S., Kampa, A., Piel, J., & Oldfield, N. J. (2015). Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases. Angewandte Chemie International Edition, 54(6), https://doi.org/10.1002/anie.201410219

Type I modular polyketide synthases (PKSs), responsible for the biosynthesis of many biologically active agents, possess a ketosynthase (KS) domain within each module to catalyze chain elongation.
Acylation of the KS active site Cys residue is foll... Read More about Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases.

Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014)
Journal Article
Bossù, P., Tsuang, D. W., Lleò, A., Wallon, D., Todd, S., Dufouil, C., …Holmans, P. (2015). Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 11(6), 658-671. https://doi.org/10.1016/j.jalz.2014.05.1757

© 2015, Elsevier Inc. All rights reserved.

Background:

Late-onset Alzheimer's disease (AD) is heritable with 20 genes showing genome-wide association in the International Genomics of Alzheimer's Project (IGAP). To identify the biology underly... Read More about Convergent genetic and expression data implicate immunity in Alzheimer's disease.

Measuring sub-mm structural displacements using QDaedalus: a digital clip-on measuring system developed for total stations (2014)
Journal Article
Charalampous, E., Psimoulis, P., Guillaume, S., Spiridonakos, M., Klis, R., Burki, B., …Feltrin, G. (2015). Measuring sub-mm structural displacements using QDaedalus: a digital clip-on measuring system developed for total stations. Applied Geomatics, 7(2), https://doi.org/10.1007/s12518-014-0150-z

The monitoring of rigid structures of modal frequencies greater than 5 Hz and sub-mm displacement is mainly based so far on relative quantities from accelerometers, strain gauges etc. Additionally geodetic techniques such as GPS and Robotic Total Sta... Read More about Measuring sub-mm structural displacements using QDaedalus: a digital clip-on measuring system developed for total stations.

Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT) (2014)
Journal Article
Weng, S. F., Kai, J., Neil, H. A., Humphries, S. E., & Qureshi, N. (2015). Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT). Atherosclerosis, 238(2), https://doi.org/10.1016/j.atherosclerosis.2014.12.034

Objective: Heterozygous familial hypercholesterolaemia (FH) is a common autosomal dominant disorder. The vast majority of affected individuals remain undiagnosed, resulting in lost opportunities for preventing premature heart disease. Better use of r... Read More about Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT).

“You can’t just jump on a bike and go”: a qualitative study exploring parents’ perceptions of physical activity in children with type 1 diabetes (2014)
Journal Article
Quirk, H., Blake, H., Dee, B., & Glazebrook, C. (2014). “You can’t just jump on a bike and go”: a qualitative study exploring parents’ perceptions of physical activity in children with type 1 diabetes. BMC Pediatrics, 14(1), https://doi.org/10.1186/s12887-014-0313-4

Background

Parents of children with Type 1 Diabetes Mellitus (T1DM) have an important role in supporting diabetes management behaviours and helping to maintain their child’s healthy lifestyle. Physical activity has known benefits for children with... Read More about “You can’t just jump on a bike and go”: a qualitative study exploring parents’ perceptions of physical activity in children with type 1 diabetes.

Effects of bowel cleansing on the intestinal microbiota (2014)
Journal Article
Jalanka, J., Salonen, A., Salojärvi, J., Ritari, J., Immonen, O., Marciani, L., …de Vos, W. M. (2015). Effects of bowel cleansing on the intestinal microbiota. Gut, 64(10), 1562-1568. https://doi.org/10.1136/gutjnl-2014-307240

Objective: An adequate bowel cleansing is essential for a successful colonoscopy. Although purgative consumption is safe for the patient, there is little consensus on how the intestinal microbiota is affected by the procedure, especially regarding th... Read More about Effects of bowel cleansing on the intestinal microbiota.

Influenza promotes collagen deposition via ?v?6 integrin-mediated transforming growth factor ? activation. (2014)
Journal Article

Mesenchymal stromal cells express GARP/LRRC32 on their surface: Effects on their biology and immunomodulatory capacity (2014)
Journal Article
Carrillo-Galvez, A. B., Cobo, M., Cuevas-Ocaña, S., Gutiérrez-Guerrero, A., Sánchez-Gilabert, A., Bongarzone, P., …Anderson, P. (2015). Mesenchymal stromal cells express GARP/LRRC32 on their surface: Effects on their biology and immunomodulatory capacity. STEM CELLS, 33(1), 183-195. https://doi.org/10.1002/stem.1821

Mesenchymal stromal cells (MSCs) represent a promising tool for therapy in regenerative medicine, transplantation, and autoimmune disease due to their trophic and immunomodulatory activities. However, we are still far from understanding the mechanism... Read More about Mesenchymal stromal cells express GARP/LRRC32 on their surface: Effects on their biology and immunomodulatory capacity.

Rumour and Radiation: Sound in Video Art (2014)
Book
HEGARTY, P. (2015). Rumour and Radiation: Sound in Video Art. New York: Bloomsbury Publishing

This is a book about video art, and about sound art.

The thesis is that sound first entered the gallery via the video art of the 1960s and in so doing, created an unexpected noise. The early part of the book looks at this formative period and the... Read More about Rumour and Radiation: Sound in Video Art.

Recognition of Haptic Interaction Patterns in Dyadic Joint Object Manipulation (2014)
Journal Article
Madan, C. E., Kucukyilmaz, A., Sezgin, T. M., & Basdogan, C. (2015). Recognition of Haptic Interaction Patterns in Dyadic Joint Object Manipulation. IEEE Transactions on Haptics, 8(1), 54-66. https://doi.org/10.1109/toh.2014.2384049

The development of robots that can physically cooperate with humans has attained interest in the last decades. Obviously, this effort requires a deep understanding of the intrinsic properties of interaction. Up to now, many researchers have focused o... Read More about Recognition of Haptic Interaction Patterns in Dyadic Joint Object Manipulation.

The Iron Cage of Liberalism: International Politics and Unarmed Revolutions in the Middle East and North Africa (2014)
Book
Ritter, D. (2014). The Iron Cage of Liberalism: International Politics and Unarmed Revolutions in the Middle East and North Africa. Oxford University Press. https://doi.org/10.1093/acprof%3Aoso/9780199658329.001.0001

Revolutions no longer stand to be recognized. In contrast to the processes of political and social change spearheaded—and romanticized—by revolutionaries like Lenin and Mao, contemporary revolutions no longer require violent struggle in order to secu... Read More about The Iron Cage of Liberalism: International Politics and Unarmed Revolutions in the Middle East and North Africa.

Variation in the inter-service intervals of UK dairy cows (2014)
Journal Article
Remnant, J., Green, M. J., Huxley, J., & Hudson, C. (2015). Variation in the inter-service intervals of UK dairy cows. Journal of Dairy Science, 98(2), https://doi.org/10.3168/jds.2014-8366

An understanding of the normal estrous cycle length of the cow is important when managing and monitoring dairy herd fertility. Whilst the normal inter-ovulatory interval is widely considered to be 21 days, some studies have found alternative interval... Read More about Variation in the inter-service intervals of UK dairy cows.

Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs (2014)
Journal Article
Naqid, I. A., Owen, J. P., Maddison, B. C., Gardner, D. S., Foster, N., Tchorzewska, M., La Ragione, R. M., & Gough, K. C. (2015). Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs. Animal Feed Science and Technology, 201, 57-65. https://doi.org/10.1016/j.anifeedsci.2014.12.005

Salmonellosis causes significant economic losses to the pig industry and contaminated pork products are an important source of Salmonella for humans. The EU ban on the use of antibiotic growth promoters in pig production, and the emergence of antibio... Read More about Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs.

An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom (2014)
Journal Article
Bradley, A., Breen, J., Payne, B., White, V., & Green, M. (2015). An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom. Journal of Dairy Science, 98(3), https://doi.org/10.3168/jds.2014-8332

Vaccination can play a useful role in mastitis control programs, although there is a relative dearth of large, well-controlled field efficacy studies. This paper presents the findings on the use of a commercially available vaccine (Startvac, Hipra UK... Read More about An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom.

Data-informed fuzzy measures for fuzzy integration of intervals and fuzzy numbers (2014)
Journal Article
Havens, T. C., Anderson, D. T., & Wagner, C. (2015). Data-informed fuzzy measures for fuzzy integration of intervals and fuzzy numbers. IEEE Transactions on Fuzzy Systems, 23(5), https://doi.org/10.1109/TFUZZ.2014.2382133

The fuzzy integral (FI) with respect to a fuzzy measure (FM) is a powerful means of aggregating information. The most popular FIs are the Choquet and Sugeno, and most research focuses on these two variants. The arena of the FM is much more populated,... Read More about Data-informed fuzzy measures for fuzzy integration of intervals and fuzzy numbers.

Contrasting patterns of turnover between plants, pollinators and their interactions (2014)
Journal Article
Norfolk, O., Eichhorn, M. P., & Gilbert, F. S. (2015). Contrasting patterns of turnover between plants, pollinators and their interactions. Diversity and Distributions, 21(4), https://doi.org/10.1111/ddi.12295

Aim: Biogeographers typically assess patterns of diversity across landscapes. As interacting groups often exhibit contrasting trends, this leads to variation in the structure of interaction networks and thereby influences ecosystem processes. Here we... Read More about Contrasting patterns of turnover between plants, pollinators and their interactions.

Beyond risk-taking: effects of psychological safety on cooperative goal interdependence and prosocial behavior (2014)
Journal Article
Leung, K., Deng, H., Wang, J., & Zhou, F. (2015). Beyond risk-taking: effects of psychological safety on cooperative goal interdependence and prosocial behavior. Group and Organization Management, 40(1), https://doi.org/10.1177/1059601114564012

In addition to risk-taking behavior, we propose that psychological safety also promotes prosocial behavior through cooperative goal interdependence. To differentiate these two types of effects, we contrasted the moderating effects of two interpersona... Read More about Beyond risk-taking: effects of psychological safety on cooperative goal interdependence and prosocial behavior.

Screening for celiac disease in the general population and in high-risk groups (2014)
Journal Article
Ludvigsson, J. F., Card, T. R., Kaukinen, K., Bai, J., Zingone, F., Sanders, D. S., & Murray, J. A. (in press). Screening for celiac disease in the general population and in high-risk groups. United European Gastroenterology Journal, 3(2), https://doi.org/10.1177/2050640614561668

BACKGROUND: Celiac disease (CD) occurs in approximately 1% of the Western population. It is a lifelong disorder that is associated with impaired quality of life (QOL) and an excessive risk of comorbidity and death.

OBJECTIVES: To review the liter... Read More about Screening for celiac disease in the general population and in high-risk groups.

Performance evaluation of an energy storage system for household applications (2014)
Presentation / Conference Contribution
Klumpner, C. (2014). Performance evaluation of an energy storage system for household applications.

This presentation shows the progress made on the Supercapattery for household applications as of December 2014.

Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study (2014)
Journal Article
Alkahtani, S. A., Cherrill, J., Millward, C., Grayson, K., Hilliam, R., Sammons, H., & Choonara, I. (2014). Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study. BMJ Open, 4, Article e006421. https://doi.org/10.1136/bmjopen-2014-006421

Objectives: To explore access to primary healthcare and drug therapy by refugee children in the East Midlands region of England.
Design: Interviews with refugees with children and a control group of British parents with children.
Setting: East Midl... Read More about Access to medicines by child refugees in the East Midlands region of England: a cross-sectional study.