Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs

Naqid, Ibrahim A.; Owen, Jonathan P.; Maddison, Ben C.; Gardner, David S.; Foster, Neil; Tchorzewska, Monika; La Ragione, Roberto M.; Gough, Kevin C.

Abstract

Salmonellosis causes significant economic losses to the pig industry and contaminated pork products are an important source of Salmonella for humans. The EU ban on the use of antibiotic growth promoters in pig production, and the emergence of antibiotic resistance has meant there is a pressing need for alternative control strategies for pathogenic bacteria such as S. Typhimurium in pigs. Here, we determined the effects of prebiotic, probiotic and synbiotic diet regimes on antibody responses to oral Salmonella challenge of pigs. The data demonstrate that the inclusion of the probiotic Lactobacillus plantarum B2984 in the diet of piglets (∼1 × 1010 cfu/animal/day) enhanced serum IgM (P

Citation

Naqid, I. A., Owen, J. P., Maddison, B. C., Gardner, D. S., Foster, N., Tchorzewska, M., …Gough, K. C. (2015). Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs. Animal Feed Science and Technology, 201, 57-65. https://doi.org/10.1016/j.anifeedsci.2014.12.005

• Journal Article Type: Article
• Acceptance Date: Dec 6, 2014
• Online Publication Date: Dec 18, 2014
• Publication Date: 2015-03
• Deposit Date: Sep 24, 2015
• Publicly Available Date: Sep 24, 2015
• Journal: Animal Feed Science and Technology
• Print ISSN: 0377-8401
• Electronic ISSN: 0377-8401
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 201
• Pages: 57-65
• DOI: https://doi.org/10.1016/j.anifeedsci.2014.12.005
• Keywords: Prebiotic; Probiotic; Synbiotic; Immune response; Salmonella; Salmonellosis
• Public URL: https://nottingham-repository.worktribe.com/output/984727
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0377840114004064