All Outputs (672)

Associations between udder health and reproductive performance in United Kingdom dairy cows (2012)
Journal Article
Hudson, C., Bradley, A. J., Breen, J., & Green, M. J. (2012). Associations between udder health and reproductive performance in United Kingdom dairy cows. Journal of Dairy Science, 95(7), https://doi.org/10.3168/jds.2011-4629

The objective of this research was to evaluate the relationship between udder health and reproductive performance in UK dairy cows. Data from 80 herds were restructured such that each unit of data represented a 2-d period during lactation where a cow... Read More about Associations between udder health and reproductive performance in United Kingdom dairy cows.

Collaborative knowledge building with shared video representations: Special Issue on supporting shared representations in collaborative activities (2012)
Journal Article
BARTHEL, R., AINSWORTH, S., & SHARPLES, M. (2013). Collaborative knowledge building with shared video representations: Special Issue on supporting shared representations in collaborative activities. International Journal of Human-Computer Studies, 71(1), 59--75. https://doi.org/10.1016/j.ijhcs.2012.02.006

Online video has become established as a fundamental part of the fabric of the web; widely used by people for information sharing, learning and entertainment. We report results from a design study that explored how people interact to create shared mu... Read More about Collaborative knowledge building with shared video representations: Special Issue on supporting shared representations in collaborative activities.

Evidence and belief in regulatory decisions – incorporating expected utility into decision modelling (2012)
Journal Article
Li, J., Davies, G., Kendall, G., Soane, E., Bai, R., Rocks, S., & Pollard, S. (2012). Evidence and belief in regulatory decisions – incorporating expected utility into decision modelling. Expert Systems with Applications, 39(10), https://doi.org/10.1016/j.eswa.2012.01.193

Recent changes in the assessment and management of risks has had the effect that greater importance has been placed on relationships between individuals and within groups to inform decision making. In this paper, we provide the theoretical underpinni... Read More about Evidence and belief in regulatory decisions – incorporating expected utility into decision modelling.

A new sequential covering strategy for inducing classification rules with ant colony algorithms (2012)
Journal Article
Otero, F. E. B., Freitas, A. A., & Johnson, C. G. (2012). A new sequential covering strategy for inducing classification rules with ant colony algorithms. IEEE Transactions on Evolutionary Computation, 17(1), 64-76. https://doi.org/10.1109/TEVC.2012.2185846

Ant colony optimization (ACO) algorithms have been successfully applied to discover a list of classification rules. In general, these algorithms follow a sequential covering strategy, where a single rule is discovered at each iteration of the algorit... Read More about A new sequential covering strategy for inducing classification rules with ant colony algorithms.

In vivo confocal microscopic findings in patients with limbal stem cell deficiency (2012)
Journal Article
Miri, A., Alomar, T., Nubile, M., Al-aqaba, M., Lanzini, M., Fares, U., …Dua, H. S. (2012). In vivo confocal microscopic findings in patients with limbal stem cell deficiency. British Journal of Ophthalmology, 96(4), 523-529. https://doi.org/10.1136/bjophthalmol-2011-300551

In vivo confocal microscopic features of normal limbus (2012)
Journal Article
Miri, A., Al-Aqaba, M., Otri, A. M., Fares, U., Said, D. G., Faraj, L. A., & Dua, H. S. (2012). In vivo confocal microscopic features of normal limbus. British Journal of Ophthalmology, 96(4), 530-536. https://doi.org/10.1136/bjophthalmol-2011-300550

Handedness and the excitability of cortical inhibitory circuits (2012)
Journal Article
Reid, C. S., & Serrien, D. J. (in press). Handedness and the excitability of cortical inhibitory circuits. Behavioural Brain Research, 230(1), https://doi.org/10.1016/j.bbr.2012.02.008

Inhibitory processes play a significant role in the control of goal-directed actions. To increase insights into these mechanisms as a function of handedness, we measured the transient inhibition of volitional motor activity induced by single pulse tr... Read More about Handedness and the excitability of cortical inhibitory circuits.

The Veterinary Business Landscape: Contemporary Issues and Emerging Trends (2012)
Book Chapter
Henry, C., & Treanor, L. (2012). The Veterinary Business Landscape: Contemporary Issues and Emerging Trends. In C. C. Perez-Marin (Ed.), A Bird's-Eye View of Veterinary Medicine. InTech. https://doi.org/10.5772/31960

Investigation of the haemodynamic effects of exenatide in healthy male subjects (2012)
Journal Article
Mendis, B., Simpson, E., Macdonald, I., & Mansell, P. (2012). Investigation of the haemodynamic effects of exenatide in healthy male subjects. British Journal of Clinical Pharmacology, 74(3), 437-444. https://doi.org/10.1111/j.1365-2125.2012.04214.x

AIMS In clinical studies of glucagon-like peptide-1 (GLP-1) agonists used in the management of patients with type 2 diabetes, there is often a small accompanying fall in blood pressure. The mechanism underlying this effect is not known, although exen... Read More about Investigation of the haemodynamic effects of exenatide in healthy male subjects.

Evaluation of Rehabilitation of Memory in Neurological Disabilities (ReMiND): a randomized controlled trial (2012)
Journal Article
das Nair, R., & Lincoln, N. (in press). Evaluation of Rehabilitation of Memory in Neurological Disabilities (ReMiND): a randomized controlled trial. Clinical Rehabilitation, 26(10), https://doi.org/10.1177/0269215511435424

OBJECTIVE:The evidence for the effectiveness of memory rehabilitation is inconclusive. The aim was to compare the effectiveness of two group memory rehabilitation programmes with a self-help group control.
DESIGN:Single-blind randomized controlled t... Read More about Evaluation of Rehabilitation of Memory in Neurological Disabilities (ReMiND): a randomized controlled trial.

"Mother-weights" and lost fathers: parents in South Asian American literature (2012)
Journal Article
Maxey, R. (2012). "Mother-weights" and lost fathers: parents in South Asian American literature. Wasafiri, 27(1), https://doi.org/10.1080/02690055.2012.636892

That parent-child relationships should play a significant role within South Asian American literature is perhaps no surprise, since this is crucial material for any writer. But the particular forms they so often take – a dysfunctional mother-daughter... Read More about "Mother-weights" and lost fathers: parents in South Asian American literature.

Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness (2012)
Journal Article
Lerner, T. R., Lovering, A. L., Bui, N. K., Uchida, K., Aizawa, S., Vollmer, W., & Sockett, R. E. (2012). Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness. PLoS Pathogens, 8(2), Article e1002524. https://doi.org/10.1371/journal.ppat.1002524

Bdellovibrio are predatory bacteria that have evolved to invade virtually all Gram-negative bacteria, including many prominent pathogens. Upon invasion, prey bacteria become rounded up into an osmotically stable niche for the Bdellovibrio, preventing... Read More about Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness.

An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients (2012)
Journal Article
Hill, A. A., & Malashetty, M. (2012). An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 468(2138), https://doi.org/10.1098/rspa.2011.0137

This paper explores an operative technique for deriving nonlinear stability by studying double-diffusive porous convection with a concentration-based internal heat source. Previous stability analyses on this problem have yielded regions of potential... Read More about An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients.

Subcellular calcium dynamics in a whole-cell model of an atrial myocyte (2012)
Journal Article
Thul, R., Coombes, S., Roderick, H. L., & Bootman, M. D. (2012). Subcellular calcium dynamics in a whole-cell model of an atrial myocyte. Proceedings of the National Academy of Sciences, 109(6), 2150-2155. https://doi.org/10.1073/pnas.1115855109

In this study, we present an innovative mathematical modeling approach that allows detailed characterization of Ca 2+ movement within the three-dimensional volume of an atrial myocyte. Essential aspects of the model are the geometrically realistic re... Read More about Subcellular calcium dynamics in a whole-cell model of an atrial myocyte.

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma (2012)
Journal Article
in the microvascular niche of paediatric high grade glioma. Acta Neuropathologica, 124(1), https://doi.org/10.1007/s00401-012-0952-1

Paediatric high grade glioma (pHGG) (World Health Organisation astrocytoma grades III and IV) remains poor prognosis tumours, with a median survival of only 15 months following diagnosis. Current investigation of anti-angiogenic strategies has focuse... Read More about CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma.

Variations in structures, processes and outcomes of community mental health teams for older people: A systematic review of the literature (2012)
Journal Article
Abendstern, M., Harrington, V., Brand, C., Tucker, S., Wilberforce, M., & Challis, D. (2012). Variations in structures, processes and outcomes of community mental health teams for older people: A systematic review of the literature. Aging and Mental Health, 16(7), 861-873. https://doi.org/10.1080/13607863.2011.651431

Objectives: In the UK and elsewhere, specialist community mental health teams (CMHTs) are central to the provision of comprehensive services for older people with mental ill health. Recent guidance documents suggest a core set of attributes that such... Read More about Variations in structures, processes and outcomes of community mental health teams for older people: A systematic review of the literature.

Baby knows best? The impact of weaning style on food preferences and body mass index in early childhood in a case–controlled sample (2012)
Journal Article
Townsend, E., & Pitchford, N. J. (2012). Baby knows best? The impact of weaning style on food preferences and body mass index in early childhood in a case–controlled sample. BMJ Open, 2(1), Article e000298. https://doi.org/10.1136/bmjopen-2011-000298

Objective The impact of different weaning methods on food preferences and body mass index (BMI) in early childhood is not known. Here, we examine if weaning method—baby-led weaning versus traditional spoon feeding—influences food preferences and heal... Read More about Baby knows best? The impact of weaning style on food preferences and body mass index in early childhood in a case–controlled sample.

Evaluating the travel, physical activity and carbon impacts of a 'natural experiment' in the provision of new walking and cycling infrastructure: Methods for the core module of the iConnect study (2012)
Journal Article
Ogilvie, D., Bull, F., Cooper, A., Rutter, H., Adams, E., Brand, C., …Song, Y. (2012). Evaluating the travel, physical activity and carbon impacts of a 'natural experiment' in the provision of new walking and cycling infrastructure: Methods for the core module of the iConnect study. BMJ Open, 2, Article e000694. https://doi.org/10.1136/bmjopen-2011-000694

Introduction: Improving infrastructure to support walking and cycling is often regarded as fundamental to encouraging their widespread uptake. However, there is little evidence that specific provision of this kind has led to a significant increase in... Read More about Evaluating the travel, physical activity and carbon impacts of a 'natural experiment' in the provision of new walking and cycling infrastructure: Methods for the core module of the iConnect study.

Construction of synthetic regulatory networks in yeast (2012)
Journal Article
Blount, B. A., Weenink, T., & Ellis, T. (2012). Construction of synthetic regulatory networks in yeast. FEBS Letters, 586(15), 2112-2121. https://doi.org/10.1016/j.febslet.2012.01.053

Yeast species such as Saccharomyces cerevisiae have been exploited by humans for millennia and so it is therefore unsurprising that they are attractive cells to re-engineer for industrial use. Despite many beneficial traits yeast has for synthetic bi... Read More about Construction of synthetic regulatory networks in yeast.

Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation. (2012)
Journal Article
McRobb, F. M., Crosby, I. T., Yuriev, E., Lane, J. R., & Capuano, B. (2012). Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation. Journal of Medicinal Chemistry, 55(4), 1622-1634. https://doi.org/10.1021/jm201420s

To date all typical and atypical antipsychotics target the dopamine D(2) receptor. Clozapine represents the best-characterized atypical antipsychotic, although it displays only moderate (submicromolar) affinity for the dopamine D(2) receptor. Herein,... Read More about Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation..