All Outputs (691)

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development (2012)
Journal Article
Almeida, R. D., Loose, M., Sottile, V., Matsa, E., Denning, C., Young, L., Johnson, A. D., Gering, M., & Ruzov, A. (2012). 5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development. Epigenetics, 7(4), https://doi.org/10.4161/epi.19375

5-hydroxymethyl-cytosine (5-hmc) is a cytosine modification that is relatively abundant in mammalian pre-implantation
embryos and embryonic stem cells (Esc) derived from mammalian blastocysts. Recent observations imply that both
5-hmc and Tet1/2/... Read More about 5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

Salt release from potato crisps (2012)
Journal Article
Tian, X., & Fisk, I. D. (2012). Salt release from potato crisps. Food and Function, 3(4), https://doi.org/10.1039/C2FO10282J

The rate of salt release in-mouth from salted potato crisps was evaluated. It was hypothesised that
a slow steady release of sodium would occur on chewing and hydration; to test this a crisp was chewed
and held in the oral cavity without swallowing... Read More about Salt release from potato crisps.

Using evolutionary algorithms for fitting high-dimensional models to neuronal data (2012)
Journal Article
Svensson, C.-M., Coombes, S., & Peirce, J. (2012). Using evolutionary algorithms for fitting high-dimensional models to neuronal data. Neuroinformatics, 10(2), https://doi.org/10.1007/s12021-012-9140-7

n the study of neurosciences, and of complex biological systems in general, there is frequently a need to fit mathematical models with large numbers of parameters to highly complex datasets. Here we consider algorithms of two different classes, gradi... Read More about Using evolutionary algorithms for fitting high-dimensional models to neuronal data.

In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. (2012)
Presentation / Conference Contribution
Baker, J. G., Mistry, S. N., Fischer, P. M., Hill, S. J., Gardiner, S. M., & Kellam, B. In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. Presented at British Pharmacological Society 4th Focused Meeting on Cell Signalling

What counts as inclusion? (2012)
Journal Article
Walton, E., & Nel, N. (2012). What counts as inclusion?. Africa Education Review, 9(1), 1-26. https://doi.org/10.1080/18146627.2012.683606

In the years since the publication in South Africa of White Paper Six: Special needs education (Department of Education (DoE) 2001) various schools in the state and independent sectors have begun to implement inclusive policies and practices. With re... Read More about What counts as inclusion?.

Commentary (2012)
Journal Article
Blake, H. (2012). Commentary. International Journal of Therapy and Rehabilitation, 19(3), 143. https://doi.org/10.12968/ijtr.2012.19.3.143

[This is a commentary on: Tai Chi intervention for older adults using assistive devices in a senior living community: a pilot study (https://www.magonlinelibrary.com/doi/abs/10.12968/ijtr.2012.19.3.136?journalCode=ijtr)]

HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4+ T Cells and Promotes T-Cell Activation (2012)
Journal Article
Wang, J.-H., St. Gelais, C., Coleman, C. M., & Wu, L. (2012). HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4+ T Cells and Promotes T-Cell Activation. PLoS ONE, 7(3), Article e34521. https://doi.org/10.1371/journal.pone.0034521

The dendritic cell algorithm for intrusion detection (2012)
Book Chapter
Gu, F., Greensmith, J., & Aickelin, U. (2012). The dendritic cell algorithm for intrusion detection. In P. Lio, & D. Verma (Eds.), Biologically inspired networking and sensing : algorithms and architectures. IGI Global

As one of the solutions to intrusion detection problems, Artificial Immune Systems (AIS) have shown their advantages. Unlike genetic algorithms, there is no one archetypal AIS, instead there are four major paradigms. Among them, the Dendritic Cell Al... Read More about The dendritic cell algorithm for intrusion detection.

The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent (2012)
Journal Article
Al-Ghouleh, A., Johal, R., Sharquie, I. K., Emara, M., Harrington, H., Shakib, F., & Ghaemmaghami, A. M. (2012). The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent. PLoS ONE, 7(3), Article 11. https://doi.org/10.1371/journal.pone.0033929

Allergens are initiators of both innate and adaptive immune responses. They are recognised at the site of entry by epithelial and dendritic cells (DCs), both of which activate innate inflammatory circuits that can collectively induce Th2 immune respo... Read More about The glycosylation pattern of common allergens: the recognition and uptake of Der p 1 by epithelial and dendritic cells is carbohydrate dependent.

Promotionalism, Motivationalism and Reasons to Perform Physically Impossible Actions (2012)
Journal Article
Sinclair, N. (2012). Promotionalism, Motivationalism and Reasons to Perform Physically Impossible Actions. Ethical Theory and Moral Practice, 15(5), 647-659. https://doi.org/10.1007/s10677-012-9360-9

In this paper I grant the Humean premise that some reasons for action are grounded in the desires of the agents whose reasons they are. I then consider the question of the relation between the reasons and the desires that ground them. According to pr... Read More about Promotionalism, Motivationalism and Reasons to Perform Physically Impossible Actions.

Achieving the desired transformer leakage inductance necessary in DC-DC converters for energy storage applications (2012)
Presentation / Conference Contribution
De, D., Klumpner, C., Rashed, M., Patel, C., Kulsangcharoen, P., & Asher, G. Achieving the desired transformer leakage inductance necessary in DC-DC converters for energy storage applications. Presented at 6th IET International Conference on Power Electronics, Machines and Drives (PEMD 2012)

This paper presents a cost effective winding design and evaluation of a medium frequency isolation transformer typically used in bidirectional isolated DC/DC converters. Since leakage inductance and winding resistance of a high frequency transformer... Read More about Achieving the desired transformer leakage inductance necessary in DC-DC converters for energy storage applications.

On the impact of Cu dispersion on CO2 photoreduction over Cu/TiO2 (2012)
Journal Article
Fernández, Y., Liu, D., Mackintosh, S., Ola, O., Maroto-Valer, M., Parlett, C. M., Lee, A. F., & Wu, J. C. (2012). On the impact of Cu dispersion on CO2 photoreduction over Cu/TiO2. Catalysis Communications, 25, 78-82. https://doi.org/10.1016/j.catcom.2012.03.025

A family of Cu/TiO2 catalysts was prepared using a refined sol–gel method, and tested in the photocatalytic reduction of CO2 by H2O to CH4 using a stirred batch, annular reactor. The resulting photoactivity was benchmarked against pure TiO2 nanoparti... Read More about On the impact of Cu dispersion on CO2 photoreduction over Cu/TiO2.

Molecular studies to identify the Fusarium species responsible for HT-2 and T-2 mycotoxins in UK oats (2012)
Journal Article
Edwards, S. G., Imathiu, S. M., Ray, R. V., Back, M., & Hare, M. C. (2012). Molecular studies to identify the Fusarium species responsible for HT-2 and T-2 mycotoxins in UK oats. International Journal of Food Microbiology, 156(2), 168-175. https://doi.org/10.1016/j.ijfoodmicro.2012.03.020

High levels of Fusarium mycotoxins HT-2 and T-2 have been detected in UK oats since surveys started in 2002. Fusarium langsethiae and the closely related species F. sporotrichioides have previously been associated with the contamination of cereals wi... Read More about Molecular studies to identify the Fusarium species responsible for HT-2 and T-2 mycotoxins in UK oats.

A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools (2012)
Journal Article
Perez, E., & Edmonds, B. A. (2012). A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools. PLoS ONE, 7(3), Article e31831. https://doi.org/10.1371/journal.pone.0031831

Objective: A systematic review was conducted to identify and quality assess how studies published since 1999 have
measured and reported the usage of hearing aids in older adults. The relationship between usage and other dimensions of hearing aid out... Read More about A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools.

Mechanical properties of the bovine claw horn during lactation (2012)
Journal Article
Winkler, B., & Margerison, J. K. (2012). Mechanical properties of the bovine claw horn during lactation. Journal of Dairy Science, 95(4), 1714-1728. https://doi.org/10.3168/jds.2011-4489

Claw horn disorders are one of the main causes of lameness in dairy cows globally. This study aimed to develop material testing techniques to assess changes in the mechanical properties of bovine claw horn (BCH) and to compare these mechanical proper... Read More about Mechanical properties of the bovine claw horn during lactation.

Neuronal spike-train responses in the presence of threshold noise (2012)
Journal Article
Coombes, S., Thul, R., Laudanski, J., Palmer, A., & Sumner, C. (in press). Neuronal spike-train responses in the presence of threshold noise. Frontiers in Life Science, 5(3-4), https://doi.org/10.1080/21553769.2011.556016

The variability of neuronal firing has been an intense topic of study for many years. From a modelling perspective it has often been studied in conductance based spiking models with the use of additive or multiplicative noise terms to represent chan... Read More about Neuronal spike-train responses in the presence of threshold noise.

Coupling of kinesin ATP turnover to translocation and microtubule regulation: One engine, many machines (2012)
Journal Article
Friel, C. T., & Howard, J. (2012). Coupling of kinesin ATP turnover to translocation and microtubule regulation: One engine, many machines. Journal of Muscle Research and Cell Motility, 33(6), 377-383. https://doi.org/10.1007/s10974-012-9289-6

The cycle of ATP turnover is integral to the action of motor proteins. Here we discuss how variation in this cycle leads to variation of function observed amongst members of the kinesin superfamily of microtubule associated motor proteins. Variation... Read More about Coupling of kinesin ATP turnover to translocation and microtubule regulation: One engine, many machines.

Theory, Practice, and Crisis: Changing Economic Geographies of Money and Finance (2012)
Book Chapter
Hall, S. (2012). Theory, Practice, and Crisis: Changing Economic Geographies of Money and Finance. In T. J. Barnes, J. Peck, & E. Sheppard (Eds.), The Wiley‐Blackwell Companion to Economic Geography (91-103). Wiley-Blackwell. https://doi.org/10.1002/9781118384497.ch5

Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects (2012)
Journal Article
Bodi, Z., Zhong, S., Mehra, S., Song, J., Graham, N., Li, H., May, S., & Fray, R. G. (2012). Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects. Frontiers in Plant Science, 3(48), Article 48. https://doi.org/10.3389/fpls.2012.00048

We previously showed that the N6-methyladenosine (m6A) mRNA methylase is essential during Arabidopsis thaliana embryonic development. We also demonstrated that this modification is present at varying levels in all mature tissues. However, the require... Read More about Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects.

Synthetic peptides derived from an N-terminal domain of the E2 protein of GB virus C in the study of GBV-C/HIV-1 co-infection (2012)
Journal Article
Fernández, L., Chan, W. C., Egido, M., Gómara, M. J., & Haro, I. (2012). Synthetic peptides derived from an N-terminal domain of the E2 protein of GB virus C in the study of GBV-C/HIV-1 co-infection. Journal of Peptide Science, 18(5), 326-335. https://doi.org/10.1002/psc.2403

Synthetic peptides derived from GB virus C (GBV-C) have previously been studied in our group for the development of new systems capable of diagnosing diseases caused by this humanotropic virus. We also recently described specific peptide domains of t... Read More about Synthetic peptides derived from an N-terminal domain of the E2 protein of GB virus C in the study of GBV-C/HIV-1 co-infection.