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Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition (2010)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C., & Cassaday, H. J. (2010). Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition. Neuroscience, 170(1), https://doi.org/10.1016/j.neuroscience.2010.06.066

Latent inhibition (LI) refers to the reduction in conditioning to a stimulus that has received repeated non-reinforced pre-exposure. Investigations into the neural substrates of LI have focused on the nucleus accumbens (NAc) and its inputs from the h... Read More about Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition.

Protease sensing with nanoparticle based platforms (2010)
Journal Article
Welser, K., Adsley, R., Moore, B. M., Chan, W. C., & Aylott, J. W. (2011). Protease sensing with nanoparticle based platforms. Analyst, 136(1), 29-41. https://doi.org/10.1039/c0an00429d

Nanoparticulate systems in various unique configurations are highly effective at detecting protease activity both in vivo and in vitro. In this article, we have summarised the conventional modern methods for monitoring protease activity, and critical... Read More about Protease sensing with nanoparticle based platforms.

Changing patterns of care coordination within old-age services in England (2010)
Journal Article
Sutcliffe, C., Hughes, J., Chester, H., Xie, C., & Challis, D. (2010). Changing patterns of care coordination within old-age services in England. Care Management Journals, 11(3), 156-165. https://doi.org/10.1891/1521-0987.11.3.157

There has been a focus internationally in recent years on policies and strategies to divert the long-term care of frail older people away from residential and nursing home care and enhance provision of community-based care by improving care coordinat... Read More about Changing patterns of care coordination within old-age services in England.

Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage (2010)
Journal Article
Ala'Aldeen, D. A., Flint, M., Oldfield, N. J., Omer, S. A., McNeil, L. K., Jiang, Q., Murphy, E., Giardina, P. C., Novikova, E. G., Dodge-Scully, I. L., Bayliss, C. D., Turner, D. P., Neal, K. R., Hoiseth, S. K., Jansen, K. U., & Anderson, A. S. (2010). Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage. Vaccine, 28(48), 7667-7675. https://doi.org/10.1016/j.vaccine.2010.09.038

Recombinant forms of Neisseria meningitidis factor H binding protein (fHBP) are undergoing clinical trials in candidate vaccines against serogroup B meningococcal disease. Little is known, however, about the host response to fHBP during natural carri... Read More about Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: Role of fetal exposure to β-hydroxybutyrate (2010)
Journal Article
Langley-Evans, S. C., Daniel, Z. C., Wells, C. A., Ryan, K. J., Plant, R., & Welham, S. J. (2011). Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: Role of fetal exposure to β-hydroxybutyrate. Experimental Physiology, 96(2), 203-215. https://doi.org/10.1113/expphysiol.2010.054460

Maternal undernutrition during sensitive periods of pregnancy results in offspring predisposed towards the development of a number of diseases of adulthood, including hypertension and diabetes. In order to determine the nature of any gross alteration... Read More about Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: Role of fetal exposure to β-hydroxybutyrate.

High wintertime particulate matter pollution over an offshore island (Kinmen) off southeastern China: an overview (2010)
Journal Article
Hsu, S. C., Liu, S. C., Tsai, F., Engling, G., Lin, I. I., Chou, C. K. C., Kao, S. J., Lung, S. C. C., Chan, C. Y., Lin, S. C., Huang, J. C., Chi, K. H., Chen, W. N., Lin, F. J., Huang, C. H., Kuo, C. L., Wu, T. C., & Huang, Y. T. (2010). High wintertime particulate matter pollution over an offshore island (Kinmen) off southeastern China: an overview. Journal of Geophysical Research, 115(D17), https://doi.org/10.1029/2009JD013641

Both the Yangtze River Delta (YRD) and the Pearl River Delta (PRD), the two most rapidly developing areas in eastern China, have suffered from serious air pollution, and thus, numerous investigations were devoted to studying these problems. Other are... Read More about High wintertime particulate matter pollution over an offshore island (Kinmen) off southeastern China: an overview.

Improved dynamic lexicographic ordering for multi-objective optimisation (2010)
Presentation / Conference Contribution
Castro-Gutierrez, J., Landa-Silva, D., & Moreno-Perez, J. A. Improved dynamic lexicographic ordering for multi-objective optimisation. Presented at Parallel Problem Solving from Nature - PPSN XI, Lecture Notes in Computer Science, Vol. 6239

There is a variety of methods for ranking objectives in multiobjective optimization and some are difficult to define because they require information a priori (e.g. establishing weights in a weighted approach or setting the ordering in a lexicographi... Read More about Improved dynamic lexicographic ordering for multi-objective optimisation.

TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein (2010)
Journal Article
Clarke, D. L., Clifford, R. L., Jindarat, S., Proud, D., Pang, L., Belvisi, M., & Knox, A. J. (2010). TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein. Journal of Biological Chemistry, 285(38), 29101-29110. https://doi.org/10.1074/jbc.m109.0999952

Asthmatic airway smooth muscle (ASM) expresses interferon-γ-inducible protein-10 (CXCL10), a chemokine known to mediate mast cell migration into ASM bundles that has been reported in the airways of asthmatic patients. CXCL10 is elevated in patients s... Read More about TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein.

CODEA : an agent based multi-objective optimization framework (2010)
Presentation / Conference Contribution
Castro-Gutierrez, J., Landa-Silva, D., & Moreno-Perez, J. CODEA : an agent based multi-objective optimization framework. Presented at VII Congreso Espaol sobre Metaheursticas, Algoritmos Evolutivos y Bioinspirados (MAEB 2010)

This work presents CODEA, a COoperative DEcentralized Architecture for Multiobjective Optimization. CODEA is an objectoriented framework that aims at the creation of groups of agents to tackle complex problems by cooperative search. This cooperation... Read More about CODEA : an agent based multi-objective optimization framework.

On the relevance of the mathematics curriculum to young people (2010)
Journal Article
Sealey, P., & Noyes, A. (2010). On the relevance of the mathematics curriculum to young people. Curriculum Journal, 21(3), https://doi.org/10.1080/09585176.2010.504573

In this paper we draw upon focus group data from a large study of learner trajectories through 14-19 mathematics education to think about the notion of relevance in the mathematics curriculum. Drawing on data from three socially distanced sites we e... Read More about On the relevance of the mathematics curriculum to young people.

A multicentre randomised controlled trial of day hospital-based falls prevention programme for a screened population of community-dwelling older people at high risk of falls (2010)
Journal Article
Conroy, S., Kendrick, D., Harwood, R., Gladman, J., Coupland, C., Sach, T., Drummond, A., Youde, J., Edmans, J., & Masud, T. (2010). A multicentre randomised controlled trial of day hospital-based falls prevention programme for a screened population of community-dwelling older people at high risk of falls. Age and Ageing, 39(6), 704–710. https://doi.org/10.1093/ageing/afq096

Objective:

To determine the clinical effectiveness of a day hospital-delivered multifactorial falls prevention programme, for community-dwelling older people at high risk of future falls identified through a screening process.

Design:

Mult... Read More about A multicentre randomised controlled trial of day hospital-based falls prevention programme for a screened population of community-dwelling older people at high risk of falls.

Modelling office energy consumption: an agent based approach (2010)
Presentation / Conference Contribution
Zhang, T., Siebers, P.-O., & Aickelin, U. Modelling office energy consumption: an agent based approach. Presented at 3rd World Congress on Social Simulation (WCSS2010)

In this paper, we develop an agent-based model which integrates four important elements, i.e. organisational energy management policies/regulations, energy management technologies, electric appliances and equipment, and human behaviour, based on a ca... Read More about Modelling office energy consumption: an agent based approach.

Hormone transport (2010)
Book Chapter
Kerr, I. D., Carrier, D. J., & Twycross, J. (2010). Hormone transport. In The Plant Plasma Membrane (379-397). Springer. https://doi.org/10.1007/978-3-642-13431-9_17

Hormone transport in plants is a fundamental process governing all aspects of plant development. Identification and functional analysis of plasma membrane proteins, which regulate the import and export of plant hormones, is a requirement if we are to... Read More about Hormone transport.

Discrete-event simulation is dead, long live agent-based simulation! (2010)
Journal Article
Siebers, P.-O., Macal, C. M., Garnett, J., Buxton, D., & Pidd, M. (2010). Discrete-event simulation is dead, long live agent-based simulation!. Journal of Simulation, 4(3), 204-210

There has been much discussion about why agent-based simulation (ABS) is not as widely used as discrete-event simulation in Operational Research (OR) as it is in neighbouring disciplines such as Computer Science, the Social Sciences or Economics. To... Read More about Discrete-event simulation is dead, long live agent-based simulation!.

Paper mulberry (Broussonetia papyrifera) as a commensal model for human mobility in Oceania: anthropological, botanical and genetic considerations (2010)
Journal Article
Seelenfreund, D., Clarke, A., Oyanedel, N., Piña, R., Lobos, S., Matisoo-Smith, E., & Seelenfreund, A. (2010). Paper mulberry (Broussonetia papyrifera) as a commensal model for human mobility in Oceania: anthropological, botanical and genetic considerations. New Zealand Journal of Botany, 48(3-4), 231-247. https://doi.org/10.1080/0028825X.2010.520323

Paper mulberry (Broussonetia papyrifera (L.) Vent.) was one of the most widely distributed crop species in prehistoric Oceania, occurring from continental East Asia to the Polynesian islands. Its broad distribution is largely due to human-mediated di... Read More about Paper mulberry (Broussonetia papyrifera) as a commensal model for human mobility in Oceania: anthropological, botanical and genetic considerations.

Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium (2010)
Journal Article
Mohammed, I., Suleman, H., Otri, A. M., Kulkarni, B. B., Chen, P., Hopkinson, A., & Dua, H. S. (2010). Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium. Investigative Ophthalmology & Visual Science, 51(9), 4677-4682. https://doi.org/10.1167/iovs.10-5334

Purpose: Antimicrobial peptides (AMPs) are multifunctional host defense molecules. Human β-defensin 9 (HBD9) has previously been shown to be downregulated during ocular surface (OS) infection or inflammation. Here, the authors aimed to study localiz... Read More about Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium.

Optimized reprocessing of documents using stored processor state (2010)
Presentation / Conference Contribution
Ollis, J. A., Brailsford, D. F., & Bagley, S. R. Optimized reprocessing of documents using stored processor state. Presented at ACM Symposium on Document Engineering (DocEng '10)

Variable Data Printing (VDP) allows customised versions of material such as advertising flyers to be readily produced. However, VDP is often extremely demanding of computing resources because, even when much of the material stays invariant from one d... Read More about Optimized reprocessing of documents using stored processor state.

Computational study of non-linear great deluge for university course timetabling (2010)
Book Chapter
Obit, J. H., & Landa-Silva, D. (2010). Computational study of non-linear great deluge for university course timetabling. In V. Sgurev, M. Hadjiski, & J. Kacprzyk (Eds.), Intelligent systems: from theory to practice. Springer

The great deluge algorithm explores neighbouring solutions which are accepted if they are better than the best solution so far or if the detriment in quality is no larger than the current water level. In the original great deluge method, the water le... Read More about Computational study of non-linear great deluge for university course timetabling.

Transforming legal aid: access to criminal defence services (2010)
Book
Kemp, V. (2010). Transforming legal aid: access to criminal defence services. Ministry of Justice

With legal aid reform having the potential to change the organisation of criminal defence services a survey of users in the criminal justice system was undertaken. The findings helped to highlight potential barriers to legal advicea and further resea... Read More about Transforming legal aid: access to criminal defence services.