Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension
(2008)
Journal Article
Nasim, M. T., Ghouri, A., Patel, B., James, V., Rudarakanchana, N., Morrell, N. W., & Trembath, R. C. (2008). Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension. Human Molecular Genetics, 17(11), 1683-1694. https://doi.org/10.1093/hmg/ddn059
All Outputs (38870)
Modern matrons and infection control practices: aspirations and realities (2008)
Journal Article
Koteyko, N., & Nerlich, B. (2008). Modern matrons and infection control practices: aspirations and realities. British Journal of Infection Control, 9(2),Modern matrons were introduced in 2001 by the Department of Health to lead clinical teams in the prevention of healthcare associated infection. The facilitative role of modern matron requires both managerial and entrepreneurial skills and senior nurs... Read More about Modern matrons and infection control practices: aspirations and realities.
Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein (2008)
Journal Article
Owsianka, A. M., Tarr, A. W., Keck, Z. Y., Li, T. K., Witteveldt, J., Adair, R., …Patel, A. H. (2008). Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein. Journal of General Virology, 89(3), 653-659. https://doi.org/10.1099/vir.0.83386-0The humoral response to hepatitis C virus (HCV) may contribute to controlling infection. We previously isolated human monoclonal antibodies to conformational epitopes on the HCV E2 glycoprotein. Here, we report on their ability to inhibit infection b... Read More about Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.
Formulaic sequences: Are they processed more quickly than nonformulaic language by native and nonnative speakers? (2008)
Journal Article
Conklin, K., & Schmitt, N. (2008). Formulaic sequences: Are they processed more quickly than nonformulaic language by native and nonnative speakers?. Applied Linguistics, 29(1), 72-89. https://doi.org/10.1093/applin/amm022It is generally accepted that formulaic sequences like take the bull by the horns serve an important function in discourse and are widespread in language. It is also generally believed that these sequences are processed more efficiently because singl... Read More about Formulaic sequences: Are they processed more quickly than nonformulaic language by native and nonnative speakers?.
Recognition and management of pain in cattle (2008)
Journal Article
Hudson, C., Whay, H., & Huxley, J. (2008). Recognition and management of pain in cattle. In Practice, 30(3), https://doi.org/10.1136/inpract.30.3.126Attitudes towards pain and its control in farm animals have lagged behind those in companion animal species. However, a considerable amount of work over the past 15 years has focused on the perception of pain in cattle based on objective and subjecti... Read More about Recognition and management of pain in cattle.
Insulin-like factor 3 levels in amniotic fluid of human male fetuses (2008)
Journal Article
Anand-Ivell, R., Ivell, R., Driscoll, D., & Manson, J. (2008). Insulin-like factor 3 levels in amniotic fluid of human male fetuses. Human Reproduction, 23(5), 1180-1186. https://doi.org/10.1093/humrep/den038BACKGROUND: Rodent studies suggest that the peptide hormone insulin-like factor 3 (Insl3) made by the fetal testis is responsible for the first transabdominal phase of testicular descent, and may be affected by xenobiotics to disrupt male reproductiv... Read More about Insulin-like factor 3 levels in amniotic fluid of human male fetuses.
Identification and characterization of novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae (2008)
Journal Article
Oldfield, N. J., Donovan, E. A., Worrall, K. E., Wooldridge, K. G., Langford, P. R., Rycroft, A. N., & Ala'Aldeen, D. A. (2008). Identification and characterization of novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae. Vaccine, 26(16), 1942-1954. https://doi.org/10.1016/j.vaccine.2008.02.022Actinobacillus pleuropneumoniae is an important respiratory pathogen of swine, for which there is no highly effective vaccine. A phage expression library of the A. pleuropneumoniae genome was constructed and screened to identify potential vaccine com... Read More about Identification and characterization of novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae.
Safety in paediatric clinical trials - a 7-year review (2008)
Journal Article
Sammons, H., Gray, C., Hudson, H., Cherrill, J., & Choonara, I. (2008). Safety in paediatric clinical trials - a 7-year review. Acta Paediatrica, 97(4), 474-477. https://doi.org/10.1111/j.1651-2227.2008.00676.xAim: The safety of clinical trials in children has not been previously studied. We aimed to identify how safety is monitored and the extent of adverse drug reactions (ADRs).
Methods: A literature review of the Medline Database for therapeutic clin... Read More about Safety in paediatric clinical trials - a 7-year review.
The male experience of infertility: A thematic analysis of an online infertility support group bulletin board (2008)
Journal Article
Malik, S. M., & Coulson, N. (2008). The male experience of infertility: A thematic analysis of an online infertility support group bulletin board. Journal of Reproductive and Infant Psychology, 26(1), 18-30. https://doi.org/10.1080/02646830701759777Past research has suggested that men and women differ in their response to the experience of infertility. However, there is comparatively little research focusing specifically on the male perspective of infertility. The aim of this study was to exami... Read More about The male experience of infertility: A thematic analysis of an online infertility support group bulletin board.
Distinct migratory and non-migratory ecotypes of an endemic New Zealand eleotrid (Gobiomorphus cotidianus) – implications for incipient speciation in island freshwater fish species (2008)
Journal Article
Michel, C., Hicks, B. J., Stölting, K. N., Clarke, A. C., Stevens, M. I., Tana, R., …van den Heuvel, M. R. (2008). Distinct migratory and non-migratory ecotypes of an endemic New Zealand eleotrid (Gobiomorphus cotidianus) – implications for incipient speciation in island freshwater fish species. BMC Evolutionary Biology, 8(1), Article 49. https://doi.org/10.1186/1471-2148-8-49Background. Many postglacial lakes contain fish species with distinct ecomorphs. Similar evolutionary scenarios might be acting on evolutionarily young fish communities in lakes of remote islands. One process that drives diversification in island fre... Read More about Distinct migratory and non-migratory ecotypes of an endemic New Zealand eleotrid (Gobiomorphus cotidianus) – implications for incipient speciation in island freshwater fish species.
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis (2008)
Journal Article
Xavier, R. J., Huett, A., & Rioux, J. D. (2008). Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis. Gut, 57(6), 717-720. https://doi.org/10.1136/gut.2007.134254Crohns disease (CD) is a complex polygenic trait whereby multiple genetic and non-genetic risk factors contribute to disease susceptibility. Association testing is a statistical approach commonly used for identifying genetic risk factors for complex/... Read More about Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.
Effect of specimen preparation method on the stress-strain behavior of sand in plane-strain compression tests (2008)
Journal Article
Wanatowski, D., & Chu, J. (2008). Effect of specimen preparation method on the stress-strain behavior of sand in plane-strain compression tests. Geotechnical Testing Journal, 31(4), https://doi.org/10.1520/GTJ101307Experimental results are presented in this paper to study the effect of specimen preparation method on the stress-strain behavior of sand in plane-strain compression tests. The data obtained from K0 consolidation, drained, undrained and strain path t... Read More about Effect of specimen preparation method on the stress-strain behavior of sand in plane-strain compression tests.
Democratization in a passive dendritic tree: An analytical investigation (2008)
Journal Article
Timofeeva, Y., Cox, S. J., Coombes, S., & Josic, K. (2008). Democratization in a passive dendritic tree: An analytical investigation. Journal of Computational Neuroscience, 25(2), 228-244. https://doi.org/10.1007/s10827-008-0075-9One way to achieve amplification of distal synaptic inputs on a dendritic tree is to scale the amplitude and/or duration of the synaptic conductance with its distance from the soma. This is an example of what is often referred to as "dendritic democr... Read More about Democratization in a passive dendritic tree: An analytical investigation.
The genetic diversity of planktic foraminifera and the global distribution of ribosomal RNA genotypes (2008)
Journal Article
Darling, K. F., & Wade, C. M. (2008). The genetic diversity of planktic foraminifera and the global distribution of ribosomal RNA genotypes. Marine Micropaleontology, 67(3-4), 216-238. https://doi.org/10.1016/j.marmicro.2008.01.009Fossil planktic foraminifers in the ocean sediments play an unparalleled role in our understanding of the oceanographic environment in the past. An in depth knowledge of their diversity, ecology and biogeography in the modern ocean lies central to th... Read More about The genetic diversity of planktic foraminifera and the global distribution of ribosomal RNA genotypes.
Reclaiming Academia from Post-academia (2008)
Journal Article
Moriarty, P. (2008). Reclaiming Academia from Post-academia. Nature Nanotechnology, 3,Post-academic science, driven as it is by commercialisation and market forces, is fundamentally at odds with core academic principles. Publicly-funded academics have an obligation to carry out science for the public good, a responsibility which is in... Read More about Reclaiming Academia from Post-academia.
Interstitial glucose profile associated with symptoms attributed to hypoglycemia by otherwise healthy women (2008)
Journal Article
Simpson, E. J., Holdsworth, M., & Macdonald, I. A. (2008). Interstitial glucose profile associated with symptoms attributed to hypoglycemia by otherwise healthy women. American Journal of Clinical Nutrition, 87(2), 354-361. https://doi.org/10.1093/ajcn/87.2.354Background: Reports of postprandial symptoms attributed to hypoglycemia by otherwise healthy individuals appear to be relatively common in UK women. Whether these symptoms are related to blood glucose is a contentious issue, which periodic ambulatory... Read More about Interstitial glucose profile associated with symptoms attributed to hypoglycemia by otherwise healthy women.
A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand (2008)
Journal Article
Bai, R., & Kendall, G. (in press). A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand. INFORMS Journal on Computing, 20(1), https://doi.org/10.1287/ijoc.1070.0219Asignificant amount of work has investigated inventory control problems associated with fresh produce. Much of this work has considered deteriorating inventory control with many models having been proposed for various situations. However, no research... Read More about A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand.
Enhancing productivity: the role of management practices (2008)
Journal Article
Siebers, P.-O., Aickelin, U., Battisti, G., Celia, H., Clegg, C., Fu, X., Hoyos, R. D., Iona, A., Petrescu, A., & Peixoto, A. (2008). Enhancing productivity: the role of management practices. https://doi.org/10.2139/ssrn.1309605There is no doubt that management practices are linked to the productivity and performance of a company. However, research findings are mixed. This paper provides a multi-disciplinary review of the current evidence of such a relationship and offers s... Read More about Enhancing productivity: the role of management practices.
Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach (2008)
Journal Article
Crossley, N. A., Sena, E. S., Goehler, J., Horn, J., van der Worp, H. B., Bath, P. M., …Dirnagl, U. (2008). Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach. Stroke, 39, https://doi.org/10.1161/STROKEAHA.107.498725Background and Purpose: At least part of the failure in the transition from experimental to clinical studies in stroke has been attributed to the imprecision introduced by problems in the design of experimental stroke studies. Using a metaepidemiolog... Read More about Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.
A mixer design for the pigtail braid (2008)
Journal Article
Binder, B. J., & Cox, S. M. (2008). A mixer design for the pigtail braid. Fluid Dynamics Research, 40(1), 34-44. https://doi.org/10.1016/j.fluiddyn.2006.09.001The stirring of a body of viscous fluid using multiple stirring rods is known to be particularly effective when the rods trace out a path corresponding to a nontrivial mathematical braid. The optimal braid is the so-called "pigtail braid", in which t... Read More about A mixer design for the pigtail braid.