Skip to main content

Research Repository

Advanced Search

All Outputs (38511)

Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation (2024)
Journal Article
Young, K. J., Leboeuf-Yde, C., Gorrell, L., Bergström, C., Evans, D. W., Axén, I., Chance-Larsen, K., Gagey, O., Georgopoulos, V., Goncalves, G., Harris, C., Harsted, S., Kerry, R., Lee, E., McCarthy, C., Nim, C., Nyirö, L., Schweinhardt, P., & Vogel, S. (2024). Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation. Chiropractic & Manual Therapies, 32(1), Article 28. https://doi.org/10.1186/s12998-024-00549-w

Background
Spinal manipulation (SM) has been claimed to change anatomy, either in structure or position, and that these changes may be the cause of clinical improvements. The aim of this systematic review was to evaluate and synthesise the peer-revi... Read More about Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation.

Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide (2024)
Journal Article
Taher, R., Hall, C. L., Gomez Bergin, A. D., Gupta, N., Heaysman, C., Jacobsen, P., Kabir, T., Kalnad, N., Keppens, J., Hsu, C.-W., McGuire, P., Peters, E., Shergill, S., Stahl, D., Wensley Stock, B., & Yiend, J. (2024). Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide. Trials, 25, Article 604. https://doi.org/10.1186/s13063-024-08421-1

Background: The field of digital mental health has followed an exponential growth trajectory in recent years. While the evidence base has increased significantly, its adoption within health and care services has been slowed by several challenges, inc... Read More about Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide.

A systematic review of teaching Comparative and International Education (CIE) in higher education: Themes, contexts, and methods (2024)
Journal Article
Li, M., Li, S., & Yuan, T. (in press). A systematic review of teaching Comparative and International Education (CIE) in higher education: Themes, contexts, and methods. Compare: A Journal of Comparative and International Education,

This paper scrutinises the teaching of Comparative and International Education (CIE) in higher education, addressing the gap in the discourse on how CIE is taught. Utilising the latest 'Preferred Reporting Items for Systematic Reviews and Meta-Analys... Read More about A systematic review of teaching Comparative and International Education (CIE) in higher education: Themes, contexts, and methods.

Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation (2024)
Journal Article
Zeeshan, M., Rashpa, R., Ferguson, D. J., Mckeown, G., Nugmanova, R., Subudhi, A. K., Beyeler, R., Pashley, S. L., Markus, R., Brady, D., Roques, M., Bottrill, A. R., Fry, A. M., Pain, A., Vaughan, S., Holder, A. A., Tromer, E. C., Brochet, M., & Tewari, R. (2024). Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation. PLoS Biology, 22(9), Article e3002802. https://doi.org/10.1371/journal.pbio.3002802

Mitosis is an important process in the cell cycle required for cells to divide. Never in mitosis (NIMA)-like kinases (NEKs) are regulators of mitotic functions in diverse organisms. Plasmodium spp., the causative agent of malaria is a divergent unice... Read More about Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation.

Marine mammals as indicators of Anthropocene Ocean Health (2024)
Journal Article
Plön, S., Andra, K., Auditore, L., Gegout, C., Hale, P. J., Hampe, O., Ramilo-Henry, M., Burkhardt-Holm, P., Jaigirdar, A. M., Klein, L., Maewashe, M. K., Müssig, J., Ramsarup, N., Roussouw, N., Sabin, R., Shongwe, T. C., & Tuddenham, P. (2024). Marine mammals as indicators of Anthropocene Ocean Health. npj Biodiversity, 3(1), Article 24. https://doi.org/10.1038/s44185-024-00055-5

The current state of marine mammal populations reflects increasing anthropogenic impacts on the global Ocean. Adopting a holistic approach towards marine mammal health, incorporating healthy individuals and healthy populations, these taxa present ind... Read More about Marine mammals as indicators of Anthropocene Ocean Health.

Professor Klaus Fassbender: The Father of Mobile Stroke Units (2024)
Journal Article
Podlasek, A., Walter, S., Licenik, R., & Grunwald, I. (2024). Professor Klaus Fassbender: The Father of Mobile Stroke Units. Cureus, 16(9), Article e69050. https://doi.org/10.7759/cureus.69050

Professor Klaus Fassbender is a distinguished neurologist from Germany, widely recognized for his groundbreaking contributions to the fields of neurology and neurodegenerative disease. His work has been pivotal in advancing our understanding of the p... Read More about Professor Klaus Fassbender: The Father of Mobile Stroke Units.

Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis (2024)
Journal Article
Dhillon, P. S., Marei, O., Podlasek, A., Butt, W., Rice, H., de Villiers, L., Carraro do Nascimento, V., McConachie, N., Lenthall, R., Nair, S., Malik, L., Bhogal, P., Dineen, R. A., & England, T. J. (2024). Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis. Journal of Stroke and Cerebrovascular Diseases, 33(11), Article 108002. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108002

Background The efficacy and safety of endovascular thrombectomy (EVT) beyond 6 hours from stroke onset for patients with large vessel occlusion (LVO) selected without CT perfusion(CTP) or MR imaging(MRI) is undeterm... Read More about Endovascular thrombectomy vs best medical management for late presentation acute ischaemic stroke with large vessel occlusion without CT perfusion or MR imaging selection: A systematic review and meta-analysis.

A New Heteroskedasticity-Robust Test for Explosive Bubbles (2024)
Journal Article
Harvey, D. I., Leybourne, S. J., Taylor, A. M. R., & Zu, Y. (in press). A New Heteroskedasticity-Robust Test for Explosive Bubbles. Journal of Time Series Analysis,

We propose a new class of modified regression-based tests for detecting asset price bubbles designed to be robust to the presence of general forms of both conditional and unconditional heteroskedasticity in the price series. This modification, based... Read More about A New Heteroskedasticity-Robust Test for Explosive Bubbles.

Exploring general practitioners’ management of self-harm in young people: a qualitative study (2024)
Journal Article
Mughal, F., Saunders, B., Lewis, M., Armitage, C., Dikomitis, L., Lancaster, G., Townsend, E., & Chew-Graham, C. A. (2024). Exploring general practitioners’ management of self-harm in young people: a qualitative study. Health Expectations, 27(5), Article e70026. https://doi.org/10.1111/hex.70026

Background
General practitioners (GPs) are key to the frontline assessment and treatment of young people after self-harm. Young people value GP-led self-harm care but little is known about how GPs manage young people after self-harm.

Aim
To und... Read More about Exploring general practitioners’ management of self-harm in young people: a qualitative study.

Does Political Corruption Reduce Pro-Social Behavior by Bureaucrats? Lab Experimental Evidence from Bangladesh (2024)
Journal Article
Woodhouse, E. F., Meyer-Sahling, J.-H., Sass Mikkelsen, K., Schuster, C., Maruful Islam, K., & Rahman, T. (in press). Does Political Corruption Reduce Pro-Social Behavior by Bureaucrats? Lab Experimental Evidence from Bangladesh. Governance,

Numerous studies assess how politicians control and shape bureaucracy. Yet, how politicians’ behavior affects the norms and behaviors of bureaucrats through role modeling has not been studied. This is a curious omission, in light of evidence that soc... Read More about Does Political Corruption Reduce Pro-Social Behavior by Bureaucrats? Lab Experimental Evidence from Bangladesh.

Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges (2024)
Journal Article
Hall, C. L., Gómez Bergin, A. D., & Rennick-Egglestone, S. (2024). Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges. Journal of Medical Internet Research, 26, Article e58939. https://doi.org/10.2196/58939

Digital mental health interventions are routinely integrated into mental health services internationally, and can contribute to the reduction of the global mental health treatment gap that has been identified by the World Health Organisation. Researc... Read More about Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges.

Paving the Road While Walking – Perspectives from Flexible Assertive Community Treatment Managers on Preparing the Implementation of Peer Support Work (PSW) in Outpatient Services (2024)
Journal Article
Johansen, K. K., Lerbaek, B., Slade, M., Castelein, S., & Jørgensen, R. (2024). Paving the Road While Walking – Perspectives from Flexible Assertive Community Treatment Managers on Preparing the Implementation of Peer Support Work (PSW) in Outpatient Services. Issues in Mental Health Nursing, https://doi.org/10.1080/01612840.2024.2391848

This qualitative study explored the perspectives of Flexible Assertive Community Treatment managers on preparation and employment of peer support workers. The study was based on semi-structured interviews with managers (n = 5) in Outpatient Services... Read More about Paving the Road While Walking – Perspectives from Flexible Assertive Community Treatment Managers on Preparing the Implementation of Peer Support Work (PSW) in Outpatient Services.

Parenting in a changing climate: the relationship between talking to children aged 5-11 about climate change, family eco-behaviours and climate change anxiety (2024)
Journal Article
Jackson, J., Rawson, R., Colman, R., Kotero, Y., & Brooks-Ucheaga, M. (2024). Parenting in a changing climate: the relationship between talking to children aged 5-11 about climate change, family eco-behaviours and climate change anxiety. Global Health Economics and Sustainability, 2(3), Article 3172. https://doi.org/10.36922/ghes.3172

Climate change has a substantial impact on human health and the increased symptoms of climate change anxiety have led to a global call for action. However, data exploring the relationship between climate change, mental health, and individuals with pa... Read More about Parenting in a changing climate: the relationship between talking to children aged 5-11 about climate change, family eco-behaviours and climate change anxiety.

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. (2024)
Journal Article
Kyratzi, P., Matika, O., Brassington, A. H., Clare, C. E., Xu, J., Barrett, D. A., Emes, R. D., Archibald, A. L., Paldi, A., Sinclair, K. D., Wattis, J., & Rauch, C. (in press). Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. Physiological Genomics, https://doi.org/10.1152/physiolgenomics.00049.2024

Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and varia... Read More about Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping..

Cannabidiol and fluorinated derivative anti-cancer properties against glioblastoma multiforme cell lines, and synergy with imidazotetrazine agents (2024)
Journal Article
Brookes, A., Kindon, N., Scurr, D. J., Alexander, M. R., Gershkovich, P., & Bradshaw, T. (2024). Cannabidiol and fluorinated derivative anti-cancer properties against glioblastoma multiforme cell lines, and synergy with imidazotetrazine agents. BJC Reports, 2, Article 67. https://doi.org/10.1038/s44276-024-00088-0

Background
Glioblastoma multiforme (GBM) is an aggressive cancer with poor prognosis, partly due to resistance to the standard chemotherapy treatment, temozolomide (TMZ). Phytocannabinoid cannabidiol (CBD) has exhibited anti-cancer effects against G... Read More about Cannabidiol and fluorinated derivative anti-cancer properties against glioblastoma multiforme cell lines, and synergy with imidazotetrazine agents.

Theoretical Study on the Biosynthesis of the Mandapamates: Mechanistic Insights Using Density Functional Theory (2024)
Journal Article
Wang, D., Pattenden, G., Fow, K. L., Stocks, M. J., Hirst, J. D., & Tang, B. (2024). Theoretical Study on the Biosynthesis of the Mandapamates: Mechanistic Insights Using Density Functional Theory. Journal of Organic Chemistry, https://doi.org/10.1021/acs.joc.4c00859

Density functional theory (B3LYP-D3(BJ) and ωB97XD) calculations have been used to assess the stereochemical outcomes of the proposed transannular [4 + 2] cycloaddition pathway for the biosynthesis of mandapamate and isomandapamate from macrocyclic i... Read More about Theoretical Study on the Biosynthesis of the Mandapamates: Mechanistic Insights Using Density Functional Theory.

Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial (2024)
Journal Article
Harris, V., Holmes, J., Gbinigie, O., Rahman, N. M., Richards, D. B., Hayward, G., Dorward, J., Lowe, D. M., Standing, J. F., Breuer, J., Khoo, S., Petrou, S., Hood, K., Ahmed, H., Carson-Stevens, A., Nguyen-Van-Tam, J. S., Patel, M. G., Saville, B. R., Francis, N., Thomas, N. P. B., …Butler, C. C. (2024). Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial. Lancet Infectious Diseases, https://doi.org/10.1016/s1473-3099%2824%2900431-6

Background
No randomised controlled trials have yet reported on the effectiveness of molnupiravir on longer term outcomes for COVID-19. The PANORAMIC trial found molnupiravir reduced time to recovery in acute COVID-19 over 28 days. We aimed to repor... Read More about Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial.

Primary liver cancer risk and mortality in patients with alcohol-related cirrhosis in England and Denmark: observational cohort studies (2024)
Journal Article
Jensen, M. D., West, J., Crooks, C., Morling, J. R., Kraglund, F., Card, T., Askgaard, G., & Jepsen, P. (2024). Primary liver cancer risk and mortality in patients with alcohol-related cirrhosis in England and Denmark: observational cohort studies. American Journal of Gastroenterology, https://doi.org/10.14309/ajg.0000000000003077

Background & Aims:

Patients with alcohol-related cirrhosis (ALD cirrhosis) have an increased risk of primary liver cancer (hepatocellular carcinoma [HCC] or intrahepatic cholangiocarcinoma [iCCA]). England recommends surveillance for HCC in these... Read More about Primary liver cancer risk and mortality in patients with alcohol-related cirrhosis in England and Denmark: observational cohort studies.