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Minimal models for RNA simulations (2025)
Journal Article
Thirumalai, D., Hori, N., & Nguyen, H. T. (2025). Minimal models for RNA simulations. Current Opinion in Structural Biology, 93, Article 103107. https://doi.org/10.1016/j.sbi.2025.103107

The increasing importance of RNA as a prime player in biology can hardly be overstated. Problems in RNA, such as folding and RNA–RNA interactions that drive phase separation, require cations. Because experiments alone cannot reveal the dynamics of ca... Read More about Minimal models for RNA simulations.

Regional profiling reveals a distinct glioblastoma infiltrative margin proteome (2025)
Journal Article
Kocon, A., Smith, S. J., Morentin, B., Callado, L. F., Carter, W., & Rahman, R. (2025). Regional profiling reveals a distinct glioblastoma infiltrative margin proteome. Scientific Reports, 15, Article 24021. https://doi.org/10.1038/s41598-025-09228-z

Isocitrate dehydrogenase wild-type glioblastoma, a malignant brain tumour of glial origin, confers a poor prognosis with a median survival of 12 to 16 months from diagnosis. Glioblastomas are aggressive tumours that rapidly proliferate and diffusely... Read More about Regional profiling reveals a distinct glioblastoma infiltrative margin proteome.

Patients with non-White ethnicity and from poorer social classes are sicker at initial presentation to hospital with COVID-19 infection (2025)
Journal Article
Crooks, C. J., West, J., Gazis, T., Morling, J., Simmonds, M., Juurlink, I., Briggs, S., Cruickshank, S., Hammond-Pears, S., Shaw, D., Card, T., & Fogarty, A. W. (2025). Patients with non-White ethnicity and from poorer social classes are sicker at initial presentation to hospital with COVID-19 infection. Public Health, 246, Article 105851. https://doi.org/10.1016/j.puhe.2025.105851

Objectives
During the COVID-19 pandemic, individuals from non-White and with poorer socio-economic status (SES) had higher rates of mortality than their counterparts. The hypothesis that these individuals had more severe respiratory failure at the t... Read More about Patients with non-White ethnicity and from poorer social classes are sicker at initial presentation to hospital with COVID-19 infection.

A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily (2025)
Journal Article
Parr, R. J., Santin, Y. G., Ratkevičiūte, G., Caulton, S. G., Radford, P., Gurvič, D., Jenkins, M., Doyle, M. T., Mead, L., Silale, A., Van Den Berg, B., Knowles, T. J., Sockett, R. E., Stansfeld, P. J., Laloux, G., & Lovering, A. L. (2025). A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily. Nature Communications, 16, Article 6213. https://doi.org/10.1038/s41467-025-61633-0

Outer membrane proteins (OMPs) define the surface biology of Gram-negative bacteria, with roles in adhesion, transport, catalysis and signalling. Specifically, porin beta-barrels are common diffusion channels, predominantly monomeric/trimeric in natu... Read More about A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily.

Factory Tourism in Inter-war Britain: The Spectacular Construction of Social-Democratic Mass Production (2025)
Journal Article
Hornsey, R. (in press). Factory Tourism in Inter-war Britain: The Spectacular Construction of Social-Democratic Mass Production. Modern British History,

In the 1920s and 1930s, many British manufacturers opened their factories to hundreds of thousands of ordinary consumers. In part, this was a response to an increasingly competitive market for branded household commodities, in which visitors were off... Read More about Factory Tourism in Inter-war Britain: The Spectacular Construction of Social-Democratic Mass Production.

17-year trends in radiological disease burden of multiple sclerosis at presentation (2025)
Journal Article
Taylor, M., Alrawashdeh, O., Evangelou, N., & Garjani, A. (2025). 17-year trends in radiological disease burden of multiple sclerosis at presentation. Multiple Sclerosis and Related Disorders, https://doi.org/10.1016/j.msard.2025.106607

At a population level, MS disease progression appears to have slowed in recent years. This study assessed whether earlier detection of people with potentially milder radiological disease is contributing to these observed trends in MS disease course.... Read More about 17-year trends in radiological disease burden of multiple sclerosis at presentation.

Five years of patient and public involvement and engagement (PPIE) in the development and evaluation of the Pain-at-Work Toolkit to support employees’ self-management of chronic pain at work (2025)
Journal Article
Blake, H., Abbott-Fleming, V., Greaves, S., Somerset, S., Chaplin, W. J., Wainwright, E., & Walker-Bone, K. (in press). Five years of patient and public involvement and engagement (PPIE) in the development and evaluation of the Pain-at-Work Toolkit to support employees’ self-management of chronic pain at work. Research Involvement and Engagement,

Psychiatric Comorbidity in Intellectual Developmental Disorders: A Systematic Review (2025)
Journal Article
Astilleros Martínez, B., Pilar Martin, M., & Kotera, Y. (2025). Psychiatric Comorbidity in Intellectual Developmental Disorders: A Systematic Review. British Journal of Hospital Medicine, https://doi.org/10.12968/hmed.2024.0686

Aims/Background Intellectual developmental disorders (IDD) are characterized by significant limitations in intellectual functioning and adaptive behavior, affecting conceptual, social, and practical skills. They impact 1% of the global population, w... Read More about Psychiatric Comorbidity in Intellectual Developmental Disorders: A Systematic Review.

A flaw in Sider’s vagueness argument for perdurantism: endurantism endures (2025)
Journal Article
Noonan, H. (2025). A flaw in Sider’s vagueness argument for perdurantism: endurantism endures. Analytic Philosophy, https://doi.org/10.1111/phib.12386

Sider’s vagueness argument for perdurantism (2001: 126ff.) has long been seen as one of the most powerful, or perhaps the most powerful, in the perdurantist’s arsenal. In its absence the case against endurantism is significantly weakened. Despite its... Read More about A flaw in Sider’s vagueness argument for perdurantism: endurantism endures.

Enhanced heat transfer of PCM-based heat sink augmented with plate-fins and hybrid nanoparticles for electronics cooling (2025)
Journal Article
Arshad, A., Jabbal, M., & Yan, Y. (2025). Enhanced heat transfer of PCM-based heat sink augmented with plate-fins and hybrid nanoparticles for electronics cooling. International Journal of Thermal Sciences, 218, Article 110107. https://doi.org/10.1016/j.ijthermalsci.2025.110107

Passive cooling technologies based on phase change material (PCM) reveal as emerging technique for thermal management of electronic components effciently. Therefore, the current study explores the combined effect of hybrid nanoparticles (HNPs), plate... Read More about Enhanced heat transfer of PCM-based heat sink augmented with plate-fins and hybrid nanoparticles for electronics cooling.

Enhancement of Inpatient Mortality Prognostication with Machine Learning in a Prospective Global Cohort of Patients with Cirrhosis with External Validation (2025)
Journal Article
Silvey, S., Kamath, P. S., George, J., Choudhury, A., Xie, Q., Topazian, M., Desalgn Mekonnen, H., Cao, Z., Nagral, A., Rajender Reddy, K., Adebayo, D., Asrani, S. K., Rajoriya, N., Arrese, M., Aghayeva, S., Sharma, M., Gonzalez Huezo, S., Gadano, A., Basri Yapici, H., Debzi, N., …Bajaj, J. S. (in press). Enhancement of Inpatient Mortality Prognostication with Machine Learning in a Prospective Global Cohort of Patients with Cirrhosis with External Validation. Gastroenterology,

Background and aims:
Cirrhosis is a major global burden requiring frequent hospitalizations with a high inpatient mortality. Traditional prognostic tools focused on inpatient mortality are affected by global disparities, which impacts timely manage... Read More about Enhancement of Inpatient Mortality Prognostication with Machine Learning in a Prospective Global Cohort of Patients with Cirrhosis with External Validation.

Impact of physician assistants on quality of care: rapid review (2025)
Journal Article
Cooper, N., Agius, S., Freeman, K., Church, H., Yoosoof, F., Frain, A., Frain, J., McConnell, R., Wilson, E., & Leonardi-Bee, J. (2025). Impact of physician assistants on quality of care: rapid review. BMJ, 390, Article e086358. https://doi.org/10.1136/bmj-2025-086358

Objective To determine the impact of physician assistants, compared with physicians, on quality of care in the context of an ongoing UK policy review.

Design Rapid systematic review.

Search strategy Keyword search of three databases; search and... Read More about Impact of physician assistants on quality of care: rapid review.

Managing Minds at Work: A Feasibility Pilot Cluster Randomised Controlled Trial of a Web-based Interactive Training for Managers to Promote Mental Health at Work (2025)
Journal Article
Hassard, J., Blake, H., Dulal-Arthur, T., Frost, A., Bartle, C., Yarker, J., Munir, F., Vaughan, B., Daly, G., Meyer, C., Russell, S., & Thomson, L. (in press). Managing Minds at Work: A Feasibility Pilot Cluster Randomised Controlled Trial of a Web-based Interactive Training for Managers to Promote Mental Health at Work. JMIR Mental Health,

Mapping the adaptive landscape of Batesian mimicry using 3D-printed stimuli (2025)
Journal Article
Taylor, C. H., Watson, D. J. G., Skelhorn, J., Bell, D., Burdett, S., Codyre, A., Cooley, K., Davies, J. R., Dawson, J. J., D’Cruz, T., Gandhi, S. R., Jackson, H. J., Lowe, R., Ogilvie, E., Pond, A. L., Rees, H., Richardson, J., Sains, J., Short, F., Brignell, C., …Reader, T. (2025). Mapping the adaptive landscape of Batesian mimicry using 3D-printed stimuli. Nature, https://doi.org/10.1038/s41586-025-09216-3

In a classic example of adaptation, harmless Batesian mimics gain protection from predators through resemblance to one or more unpalatable models. Mimics vary greatly in accuracy, and explaining the persistence of inaccurate mimics is an ongoing chal... Read More about Mapping the adaptive landscape of Batesian mimicry using 3D-printed stimuli.

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index (2025)
Journal Article
Ivell, R., Tilumcu, B., Alhujaili, W., & Anand‐Ivell, R. (2025). Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index. Andrology, https://doi.org/10.1111/andr.70091

Background: The constitutive Leydig cell hormone insulin-like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declinin... Read More about Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index.

Exploring stroke survivor and employer experiences of disruption within the RETurn to work After stroKE (RETAKE) trial during the COVID-19 pandemic (2025)
Journal Article
Trusson, D., Powers, K., Radford, K., Bowen, A., Craven, K., Farrin, A., McKevitt, C., Murray, J., Phillips, J., Stevens, J., & Clarke, D. (2025). Exploring stroke survivor and employer experiences of disruption within the RETurn to work After stroKE (RETAKE) trial during the COVID-19 pandemic. Frontiers in Sociology, 10, https://doi.org/10.3389/fsoc.2025.1434353

Introduction: Returning to work is a goal for many stroke survivors, with benefits for individuals and society. The ReTurn to work After stroKE (RETAKE) trial, which aimed to improve stroke survivors’ work outcomes through early stroke-specific vocat... Read More about Exploring stroke survivor and employer experiences of disruption within the RETurn to work After stroKE (RETAKE) trial during the COVID-19 pandemic.

A comparison of the molecular pharmacological properties of current short, long and ultra-long-acting β2-agonists used for asthma and COPD (2025)
Journal Article
Proudman, R. G. W., & Baker, J. G. (in press). A comparison of the molecular pharmacological properties of current short, long and ultra-long-acting β2-agonists used for asthma and COPD. Pharmacology Research and Perspectives, https://doi.org/10.22541/au.174560615.57789698/v1

β-agonists have been used in asthma for 120 years. There are two recent changes: ultra-long-acting agonists for COPD and new asthma guidelines recommending formoterol/ICS inhalers phasing out short-acting salbutamol inhalers. Few studies directly com... Read More about A comparison of the molecular pharmacological properties of current short, long and ultra-long-acting β2-agonists used for asthma and COPD.