All Outputs (26)

The experience of apathy in dementia: A qualitative study (2021)
Journal Article
Baber, W., Chang, C. Y. M., Yates, J., & Dening, T. (2021). The experience of apathy in dementia: A qualitative study. Alzheimer's and Dementia, 17(S7), Article e051411. https://doi.org/10.1002/alz.051411

Background

The presence of apathy is associated with less favourable outcomes in dementia, including more rapid functional and cognitive decline, greater disease severity and increased mortality. We aimed to explore and gain an understanding into... Read More about The experience of apathy in dementia: A qualitative study.

Diverse imaging features of adolescent glioblastoma. (2021)
Journal Article
Campion, T., Stoneham, S., Al-Busaidi, A., Kumar, A., Jaunmuktane, Z., Brandner, S., Kitchen, N., & Thust, S. (2022). Diverse imaging features of adolescent glioblastoma. BJR Case Reports, 8(2), Article 20210207. https://doi.org/10.1259/bjrcr.20210207

We highlight an unusual case of multifocal glioblastoma in an adolescent patient, manifesting as four discrete brain lesions, each distinct in appearance. Familiarity with the diverse imaging features of glioblastoma can reduce misdiagnosis and avoid... Read More about Diverse imaging features of adolescent glioblastoma..

Child and Adolescent Offending (2021)
Book Chapter
Paddock, E., Chou, S., & Browne, K. D. (2021). Child and Adolescent Offending. In J. M. Brown, & M. A. H. Horvath (Eds.), The Cambridge Handbook of Forensic Psychology (35-53). (2nd edition). Cambridge University Press (CUP). https://doi.org/10.1017/9781108848916.005

Developmental approaches to child and adolescent offending emphasise the role of individual and psychological factors when explaining the onset of offending, as well as the role of early risk and protective factors on future offending. This chapter w... Read More about Child and Adolescent Offending.

Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review (2021)
Journal Article
Jathanna, N., Podlasek, A., Sokol, A., Auer, D., Chen, X., & Jamil-Copley, S. (2021). Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review. Cardiovascular Digital Health Journal, 2(6), S21-S29. https://doi.org/10.1016/j.cvdhj.2021.11.005

Background: Accurate, rapid quantification of ventricular scar using cardiac magnetic resonance imaging (CMR) carries importance in arrhythmia management and patient prognosis. Artificial intelligence (AI) has been applied to other radiological chall... Read More about Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review.

The emergence of telehealth in orthotic services across the United Kingdom (2021)
Journal Article
Eddison, N., Healy, A., Calvert, S., & Chockalingam, N. (2023). The emergence of telehealth in orthotic services across the United Kingdom. Assistive Technology: The Offical Journal of RESNA, 35(2), 163-168. https://doi.org/10.1080/10400435.2021.1995531

COVID-19 has impacted the National Health Service provision, creating urgency for departments to adapt and adopt new ways of delivering healthcare. The purpose of this service evaluation was to determine the emergence of telehealth in orthotic servic... Read More about The emergence of telehealth in orthotic services across the United Kingdom.

Exploring Social Support in an Online Support Community for Tourette Syndrome and Tic Disorders: An Analysis of Postings (2021)
Preprint / Working Paper
Soós, M. J., Coulson, N. S., & Davies, E. B. (2021). Exploring Social Support in an Online Support Community for Tourette Syndrome and Tic Disorders: An Analysis of Postings

Background:

Online support communities have become an accessible way of gaining social, emotional, and informational support from peers and may be particularly useful for individuals with chronic conditions. To date, there have been few studies ex... Read More about Exploring Social Support in an Online Support Community for Tourette Syndrome and Tic Disorders: An Analysis of Postings.

A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial (2021)
Journal Article
Fox, C. P., Ali, A. S., McIlroy, G., Thust, S., Martinez-Calle, N., Jackson, A. E., Hopkins, L. M., Thomas, C. M., Kassam, S., Wright, J., Chaganti, S., Smith, J., Chau, I., Culligan, D., Linton, K. M., Collins, G. P., Ferreri, A. J. M., Lewis, D., Davies, A. J., Johnson, R., …Cwynarski, K. (2021). A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial. Blood Advances, 5(20), 4073-4082. https://doi.org/10.1182/bloodadvances.2021004779

Relapsed or refractory primary central nervous system lymphoma (rrPCNSL) confers a poor prognosis with no accepted standard of care. Very few prospective studies have been conducted in this patient group. This study was a multicenter phase 1/2 study... Read More about A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial.

Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK (2021)
Journal Article
Singh, J., & Hassard, J. (2021). Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK. Social Science Journal, https://doi.org/10.1080/03623319.2021.1979825

The present study investigates relations among emotional labour, emotional regulation strategies, and secondary traumatic stress (STS) in a sample of allied mental health professionals (AMHPs) in the UK. It empirically examines the relationship betwe... Read More about Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK.

Understanding long-term trends in smoking in England, 1972–2019: an age–period–cohort approach (2021)
Journal Article
Opazo Breton, M., Gillespie, D., Pryce, R., Bogdanovica, I., Angus, C., Hernandez Alava, M., Brennan, A., & Britton, J. (2022). Understanding long-term trends in smoking in England, 1972–2019: an age–period–cohort approach. Addiction, 117(5), 1392-1403. https://doi.org/10.1111/add.15696

Background and aims:

Smoking prevalence has been falling in England for more than 50 years, but remains a prevalent and major public health problem. This study used an age–period–cohort (APC) approach to measure lifecycle, historical and generati... Read More about Understanding long-term trends in smoking in England, 1972–2019: an age–period–cohort approach.

Filtration-Histogram Based Magnetic Resonance Texture Analysis (MRTA) for the Distinction of Primary Central Nervous System Lymphoma and Glioblastoma (2021)
Journal Article
MacIver, C. L., Al Busaidi, A., Ganeshan, B., Maynard, J. A., Wastling, S., Hyare, H., Brandner, S., Markus, J. E., Lewis, M. A., Groves, A. M., Cwynarski, K., & Thust, S. C. (2021). Filtration-Histogram Based Magnetic Resonance Texture Analysis (MRTA) for the Distinction of Primary Central Nervous System Lymphoma and Glioblastoma. Journal of Personalized Medicine, 11(9), Article 876. https://doi.org/10.3390/jpm11090876

Primary central nervous system lymphoma (PCNSL) has variable imaging appearances, which overlap with those of glioblastoma (GBM), thereby necessitating invasive tissue diagnosis. We aimed to investigate whether a rapid filtration histogram analysis o... Read More about Filtration-Histogram Based Magnetic Resonance Texture Analysis (MRTA) for the Distinction of Primary Central Nervous System Lymphoma and Glioblastoma.

Cardiovascular disease risk communication in NHS Health Checks: a qualitative video-stimulated recall interview study with practitioners (2021)
Journal Article
Gidlow, C., J Ellis, N., Riley, V., Cowap, L., Crone, D., Cottrell, E., Grogan, S., Chambers, R., Calvert, S., & Clark-Carter, D. (2021). Cardiovascular disease risk communication in NHS Health Checks: a qualitative video-stimulated recall interview study with practitioners. BJGP Open, 5(5), Article 0049. https://doi.org/10.3399/bjgpo.2021.0049

Background
NHS Health Check (NHSHC) is a national programme to identify and manage cardiovascular disease (CVD) risk. Practitioners delivering the programme should be competent in discussing CVD risk, but there is evidence of limited understanding... Read More about Cardiovascular disease risk communication in NHS Health Checks: a qualitative video-stimulated recall interview study with practitioners.

Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies (2021)
Journal Article
Scaife, P. J., Simpson, A., Kurlak, L. O., Briggs, L. V., Gardner, D. S., Pipkin, F. B., Jones, C. J. P., & Mistry, H. D. (2021). Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies. International Journal of Molecular Sciences, 22(14), Article 7295. https://doi.org/10.3390/ijms22147295

Up to 11% of pregnancies extend to post-term with adverse obstetric events linked to pregnancies over 42 weeks. Oxidative stress and senescence (cells stop growing and dividing by irreversibly arresting their cell cycle and gradually ageing) can resu... Read More about Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies.

Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study (2021)
Journal Article
Casado-Espada, N. M., Alvarez-Navares, A., Lozano-Lopez, M. T., Gamonal-Limcaoco, R. S., de la Iglesia-Larrad, J., Garzón, M. Á., Dening, T., & Roncero, C. (2021). Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study. Heroin Addiction And Related Clinical Problems, 23(3), 37-44

Background: Increasing opioid consumption in recent years has given rise to compelling significant concerns. Fentanyl, heroin, new psychoactive substances and prescribed opioids have been named as the main substances involved in the ‘opioid epidemic’... Read More about Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study.

Normative misperceptions of unhealthy snacking amongst 11- to 12-year-old secondary school students (2021)
Journal Article
Calvert, S., C. Dempsey, R., & Povey, R. (2021). Normative misperceptions of unhealthy snacking amongst 11- to 12-year-old secondary school students. Appetite, 166, Article 105462. https://doi.org/10.1016/j.appet.2021.105462

Younger adolescents are at an age where they have increasing control of their diet, and where peers become an important social reference for acceptable and normative dietary behaviours. These normative perceptions are often inaccurate and can lead to... Read More about Normative misperceptions of unhealthy snacking amongst 11- to 12-year-old secondary school students.

Longitudinal structural and perfusion MRI enhanced by machine learning outperforms standalone modalities and radiological expertise in high-grade glioma surveillance (2021)
Journal Article
Siakallis, L., Sudre, C. H., Mulholland, P., Fersht, N., Rees, J., Topff, L., Thust, S., Jager, R., Cardoso, M. J., Panovska-Griffiths, J., & Bisdas, S. (2021). Longitudinal structural and perfusion MRI enhanced by machine learning outperforms standalone modalities and radiological expertise in high-grade glioma surveillance. Neuroradiology, 63(12), 2047-2056. https://doi.org/10.1007/s00234-021-02719-6

Purpose: Surveillance of patients with high-grade glioma (HGG) and identification of disease progression remain a major challenge in neurooncology. This study aimed to develop a support vector machine (SVM) classifier, employing combined longitudinal... Read More about Longitudinal structural and perfusion MRI enhanced by machine learning outperforms standalone modalities and radiological expertise in high-grade glioma surveillance.

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials (2021)
Journal Article
Podlasek, A., Dhillon, P. S., Butt, W., Grunwald, I. O., & England, T. J. (2021). Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials. International Journal of Stroke, 16(6), 621-631. https://doi.org/10.1177/17474930211021353

Background: Direct mechanical thrombectomy may result in similar outcomes compared to a bridging approach with intravenous thrombolysis (IVT + MT) in acute ischemic stroke. Recent randomized controlled trials have varied in their design and noninferi... Read More about Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials.

Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG) (2021)
Journal Article
Barajas, R. F., Politi, L. S., Anzalone, N., Schöder, H., Fox, C. P., Boxerman, J. L., Kaufmann, T. J., Quarles, C. C., Ellingson, B. M., Auer, D., Andronesi, O. C., Ferreri, A. J. M., Mrugala, M. M., Grommes, C., Neuwelt, E. A., Ambady, P., Rubenstein, J. L., Illerhaus, G., Nagane, M., Batchelor, T. T., & Hu, L. S. (2021). Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG). Neuro-Oncology, 23(7), 1056-1071. https://doi.org/10.1093/neuonc/noab020

Advanced molecular and pathophysiologic characterization of primary central nervous system lymphoma (PCNSL) has revealed insights into promising targeted therapeutic approaches. Medical imaging plays a fundamental role in PCNSL diagnosis, staging, an... Read More about Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG).

Obesity is associated with reduced cerebral blood flow – modified by physical activity (2021)
Journal Article
Knight, S. P., Laird, E., Williamson, W., O'Connor, J., Newman, L., Carey, D., De Looze, C., Fagan, A. J., Chappell, M. A., Meaney, J. F., & Kenny, R. A. (2021). Obesity is associated with reduced cerebral blood flow – modified by physical activity. Neurobiology of Aging, 105, 35-47. https://doi.org/10.1016/j.neurobiolaging.2021.04.008

This study examined the associations of body mass index (BMI), waist-to-hip ratio (WHR), waist circumference (WC), and physical activity (PA) with gray matter cerebral blood flow (CBFGM) in older adults. Cross-sectional data was used from the Irish L... Read More about Obesity is associated with reduced cerebral blood flow – modified by physical activity.

Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., Clarke, J., Selby, K., Vijayan, H., Kulkarni, N., Brown, N., Sayal, K., Hollis, C., & Groom, M. J. (2021). Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 94. https://doi.org/10.1186/s40814-021-00830-2

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2021)
Journal Article
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. (2021). The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome. Journal of Neuropsychology, 15(3), 340-362. https://doi.org/10.1111/jnp.12242

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterized by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.