All Outputs (182)

How do stroke early supported discharge services achieve intensive and responsive service provision? Findings from a realist evaluation study (WISE) (2023)
Journal Article
Chouliara, N., Cameron, T., Byrne, A., Lewis, S., Langhorne, P., Robinson, T., …Fisher, R. (2023). How do stroke early supported discharge services achieve intensive and responsive service provision? Findings from a realist evaluation study (WISE). BMC Health Services Research, 23(1), Article 299. https://doi.org/10.1186/s12913-023-09290-1

Background: Stroke Early Supported Discharge (ESD) involves provision of responsive and intensive rehabilitation to stroke survivors at home and it is recommended as part of the stroke care pathway. Core components have been identified to guide the d... Read More about How do stroke early supported discharge services achieve intensive and responsive service provision? Findings from a realist evaluation study (WISE).

Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis (2023)
Journal Article
Scarpone, R., Kimkool, P., Ierodiakonou, D., Leonardi-Bee, J., Garcia-Larsen, V., Perkin, M., & Boyle, R. J. (2023). Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis. JAMA Pediatrics, https://doi.org/10.1001/jamapediatrics.2023.0142

Importance: Earlier egg and peanut introduction probably reduce risk of egg or peanut allergy, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction. Objective: This study is a systematic r... Read More about Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis.

Ethnic inequalities in COVID-19 infection, hospitalisation, intensive care admission, and death: a global systematic review and meta-analysis of over 200 million study participants (2023)
Journal Article
Irizar, P., Pan, D., Kapadia, D., Bécares, L., Sze, S., Taylor, H., …Pareek, M. (2023). Ethnic inequalities in COVID-19 infection, hospitalisation, intensive care admission, and death: a global systematic review and meta-analysis of over 200 million study participants. eClinicalMedicine, 57, Article 101877. https://doi.org/10.1016/j.eclinm.2023.101877

Background: COVID-19 has exacerbated existing ethnic inequalities in health. Little is known about whether inequalities in severe disease and deaths, observed globally among minoritised ethnic groups, relates to greater infection risk, poorer prognos... Read More about Ethnic inequalities in COVID-19 infection, hospitalisation, intensive care admission, and death: a global systematic review and meta-analysis of over 200 million study participants.

Evaluating the efficacy and safety of single-agent etoposide intra-CSF chemotherapy in children and young people with relapsed/refractory central nervous system tumours (2023)
Journal Article
Butler, A., Meijer, L., Liu, J., Chohan, M., Jalloh, I., Macarthur, D., …Dandapani, M. (2023). Evaluating the efficacy and safety of single-agent etoposide intra-CSF chemotherapy in children and young people with relapsed/refractory central nervous system tumours. Child's Nervous System, 39, 1537-1544. https://doi.org/10.1007/s00381-023-05872-w

Purpose The aim of the project was to evaluate intra-CSF etoposide administration in a palliative setting for children and young people with relapsed/refractory central nervous system (CNS) tumours, with the primary endpoints being overall survival... Read More about Evaluating the efficacy and safety of single-agent etoposide intra-CSF chemotherapy in children and young people with relapsed/refractory central nervous system tumours.

Case Series of Genetically Confirmed Index Cases of Familial Hypercholesterolemia in Primary Care (2023)
Journal Article
Kamal, A., Kanchau, J. D., Shahuri, N. S., Mohamed-Yassin, M. S., Baharudin, N., Razak, S. A., …Ramli, A. S. (2023). Case Series of Genetically Confirmed Index Cases of Familial Hypercholesterolemia in Primary Care. American Journal of Case Reports, 24, Article e939489. https://doi.org/10.12659/AJCR.939489

BACKGROUND: In Malaysia, the prevalence of genetically confirmed heterozygous familial hypercholesterolemia (FH) was reported as 1 in 427. Despite this, FH remains largely underdiagnosed and undertreated in primary care. CASE REPORT: In this case... Read More about Case Series of Genetically Confirmed Index Cases of Familial Hypercholesterolemia in Primary Care.

Induction of labour (2023)
Journal Article
Azhur, S., & Walker, K. F. (2023). Induction of labour. Obstetrics, Gynaecology and Reproductive Medicine, 33(5), 121-128. https://doi.org/10.1016/j.ogrm.2023.02.001

Induction of labour describes the artificial stimulation of the onset of labour and occurs in up to 30% of pregnancies in the United Kingdom. Both mechanical and pharmacological methods of induction of labour exist. Induction of labour is associated... Read More about Induction of labour.

Psychology Meets Biology in COVID-19: What We Know and Why It Matters for Public Health (2023)
Journal Article
Jones, E. J., Ayling, K., Wiley, C. R., Geraghty, A. W., Greer, A. L., Holt-Lunstad, J., …Vedhara, K. (2023). Psychology Meets Biology in COVID-19: What We Know and Why It Matters for Public Health. Policy Insights from the Behavioral and Brain Sciences, 10(1), 33-40. https://doi.org/10.1177/23727322221145308

Psychosocial factors are related to immune, viral, and vaccination outcomes. Yet, this knowledge has been poorly represented in public health initiatives during the COVID-19 pandemic. This review provides an overview of biopsychosocial links relevant... Read More about Psychology Meets Biology in COVID-19: What We Know and Why It Matters for Public Health.

A systematic review and meta-analysis of suicidality in autistic and possibly autistic people without co-occurring intellectual disability (2023)
Journal Article
Newell, V., Phillips, L., Jones, C., Townsend, E., Richards, C., & Cassidy, S. (2023). A systematic review and meta-analysis of suicidality in autistic and possibly autistic people without co-occurring intellectual disability. Molecular Autism, 14, Article 12. https://doi.org/10.1186/s13229-023-00544-7

Background: Suicidality is highly prevalent in autistic people without co-occurring intellectual disabilities, and high autistic traits are found in adults who have attempted suicide. However, prevalence rates for both autistic and possibly autistic... Read More about A systematic review and meta-analysis of suicidality in autistic and possibly autistic people without co-occurring intellectual disability.

A meta-analysis of the associations between insufficient sleep duration and antibody response to vaccination (2023)
Journal Article
Spiegel, K., Rey, A. E., Cheylus, A., Ayling, K., Benedict, C., Lange, T., …Van Cauter, E. (2023). A meta-analysis of the associations between insufficient sleep duration and antibody response to vaccination. Current Biology, 33(5), 998-1005.e2. https://doi.org/10.1016/j.cub.2023.02.017

Vaccination is a major strategy to control a viral pandemic. Simple behavioral interventions that might boost vaccine responses have yet to be identified. We conducted meta-analyses to summarize the evidence linking the amount of sleep obtained in th... Read More about A meta-analysis of the associations between insufficient sleep duration and antibody response to vaccination.

Wound healing and healing process in patients with diabetic foot ulcers: A survival analysis study (2023)
Journal Article
Graça Pereira, M., Vilaça, M., Pedras, S., Carvalho, A., Vedhara, K., Jesus Dantas, M., & Machado, L. (2023). Wound healing and healing process in patients with diabetic foot ulcers: A survival analysis study. Diabetes Research and Clinical Practice, 198, Article 110623. https://doi.org/10.1016/j.diabres.2023.110623

Aims: This study aimed to identify demographic, clinical, and psychological contributors to DFU healing and favorable healing process. Methods: Patients with a chronic DFU were evaluated at baseline (T0; n = 153), two months later (T1; n = 108), and... Read More about Wound healing and healing process in patients with diabetic foot ulcers: A survival analysis study.

Comparison of a Daily Smartphone App and Retrospective Questionnaire Measures of Adherence to Nicotine Replacement Therapy Among Pregnant Women: Observational Study (2023)
Journal Article
Emery, J., Naughton, F., Huang, Y., Cooper, S., McDaid, L., Dickinson, A., …Coleman, T. (2023). Comparison of a Daily Smartphone App and Retrospective Questionnaire Measures of Adherence to Nicotine Replacement Therapy Among Pregnant Women: Observational Study. JMIR Formative Research, 7, Article e35045. https://doi.org/10.2196/35045

Background: Few studies have investigated how to best measure adherence to smoking cessation medications, but continuous usage measures are recommended. Objective: In this first study of its kind, we compared methods for measuring adherence to nicoti... Read More about Comparison of a Daily Smartphone App and Retrospective Questionnaire Measures of Adherence to Nicotine Replacement Therapy Among Pregnant Women: Observational Study.

Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process (2023)
Journal Article
Shanmugavadivel, D., Liu, J. F., Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2023). Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process. BMJ Paediatrics Open, 7, Article e001771. https://doi.org/10.1136/bmjpo-2022-001771

Background The incidence of childhood cancer has risen by 15% since the 1990s. Early diagnosis is key to optimising outcomes, however diagnostic delays are widely reported. Presenting symptoms are often non-specific causing a diagnostic dilemma for c... Read More about Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process.

Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration (2023)
Journal Article
Cattell, M., Hyde, K., Bell, B., Dawson, T., Hills, T., Iyen, B., …Avery, A. (in press). Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration. European Journal of Hospital Pharmacy, Article 003515. https://doi.org/10.1136/ejhpharm-2022-003515

Objectives To describe the frequency of the different types of medication-related incidents that caused patient harm, or adverse consequences, in a major teaching hospital and investigate whether the likelihood of these incidents occurring would hav... Read More about Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration.

Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration (2023)
Journal Article
Cattell, M., Hyde, K., Bell, B., Dawson, T., Hills, T., Iyen, B., …Avery, A. (2023). Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration. European Journal of Hospital Pharmacy, 31(4), 295-300. https://doi.org/10.1136/ejhpharm-2022-003515

Objectives: To describe the frequency of the different types of medication-related incidents that caused patient harm, or adverse consequences, in a major teaching hospital and investigate whether the likelihood of these incidents occurring would hav... Read More about Retrospective review of medication-related incidents at a major teaching hospital and the potential mitigation of these incidents with electronic prescribing and medicines administration.

Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy (2023)
Journal Article
Emery, J., Mcdaid, L., Coleman, T., Cooper, S., Thomson, R., Kinahan-Goodwin, D., …Naughton, F. (2023). Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy. Nicotine and Tobacco Research, 25(7), 1310-1318. https://doi.org/10.1093/ntr/ntad030

Introduction Improving adherence to nicotine replacement therapy (NRT) in pregnancy may result in higher smoking cessation rates. Informed by the Necessities and Concerns Framework, we developed an intervention targeting pregnancy NRT adherence. To... Read More about Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy.

Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study (2023)
Journal Article
ALSumri, H., Szatkowski, L., Gibson, J., Fiaschi, L., & Bains, M. (2023). Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study. International Journal of Fertility & Sterility, 17(2), 107-114. https://doi.org/10.22074/IJFS.2022.550111.1310

Background: To understand the psychosocial experience of infertility among women with polycystic ovarian syndrome in Oman. Materials and Methods: In this qualitative study, semi-structured interviews were conducted with 20 Omani women diagnosed w... Read More about Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study.

Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada (2023)
Journal Article
Zaccardi, F., Tan, P. S., Shah, B. R., Everett, K., Clift, A. K., Patone, M., …Hippisley-Cox, J. (2023). Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada. BMC Public Health, 23(1), Article 399. https://doi.org/10.1186/s12889-023-15223-8

Background: Heterogeneous studies have demonstrated ethnic inequalities in the risk of SARS-CoV-2 infection and adverse COVID-19 outcomes. This study evaluates the association between ethnicity and COVID-19 outcomes in two large population-based coho... Read More about Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada.

“Get Data Out” Skin: national cancer registry incidence and survival rates for all registered skin tumour groups for 2013-2019 in England (2023)
Journal Article
van Bodegraven, B., Vernon, S., Eversfield, C., Board, R., Paul Craig, Gran, S., …BAD-NDRS Steering Committee, B.-N. S. C. (2023). “Get Data Out” Skin: national cancer registry incidence and survival rates for all registered skin tumour groups for 2013-2019 in England. British Journal of Dermatology, 188(6), 777-784. https://doi.org/10.1093/bjd/ljad033

Background Providing detailed skin cancer statistics, including incidence and survival, by tumour type and patient characteristics is important for up-to-date epidemiological information. Objectives To create a new clinically relevant consensus-... Read More about “Get Data Out” Skin: national cancer registry incidence and survival rates for all registered skin tumour groups for 2013-2019 in England.

Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD (2023)
Journal Article
Card, T. R., Nakafero, G., Grainge, M. J., Mallen, C. D., Van-Tam, J. S. N., Williams, H. C., & Abhishek, A. (2023). Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD. American Journal of Gastroenterology, 118(8), 1388-1394. https://doi.org/10.14309/ajg.0000000000002205

INTRODUCTION: To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) flare. METHODS: Patients with IBD vaccinated against COVID-19 who consulted for disease flare be... Read More about Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD.

Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis (2023)
Journal Article
Guillen-Guio, B., Paynton, M. L., Allen, R. J., Chin, D. P., Donoghue, L. J., Stockwell, A., …Hollox, E. J. (2024). Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis. ERJ Open Research, 10(1), 00553-2023. https://doi.org/10.1183/23120541.00553-2023

Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF, and a prior ass... Read More about Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis.