All Outputs (92)

Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams (2023)
Journal Article
Fisher, R., Russell, L., Riley-Bennett, F., Cameron, T., Walker, M., & Sackley, C. (2023). Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams. BMJ Open, 13(8), Article e071217. https://doi.org/10.1136/bmjopen-2022-071217

Objectives: In the UK, over 20% of stroke survivors leave hospital with severe disability. Limited evidence-based clinical guidance is available to support the rehabilitation of these individuals. Our previous research has focussed on establishing co... Read More about Barriers and facilitators in providing home-based rehabilitation for stroke survivors with severe disability in the UK: an online focus group study with multidisciplinary rehabilitation teams.

Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review (2023)
Journal Article
O’Sullivan, O., Ladlow, P., Steiner, K., Kuyser, D., Ali, O., Stocks, J., …Kluzek, S. (2023). Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review. Osteoarthritis and Cartilage Open, 5(3), Article 100385. https://doi.org/10.1016/j.ocarto.2023.100385

Introduction
Osteoarthritis (OA) results from various aetiologies, including joint morphology, biomechanics, inflammation, and injury. The latter is implicated in post-traumatic OA, which offers a paradigm to identify potential biomarkers enabling e... Read More about Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review.

The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease (2023)
Journal Article
Abhishek, A., Tedeschi, S. K., Pascart, T., Latourte, A., Dalbeth, N., Neogi, T., …Choi, H. K. (2023). The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease. Arthritis and Rheumatology, 75(10), 1703-1713. https://doi.org/10.1002/art.42619

Objective
Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have develo... Read More about The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.

The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease (2023)
Journal Article
Abhishek, A., Tedeschi, S. K., Pascart, T., Latourte, A., Dalbeth, N., Neogi, T., …Choi, H. K. (2023). The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease. Annals of the Rheumatic Diseases, 82(10), 1248-1257. https://doi.org/10.1136/ard-2023-224575

Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have develop... Read More about The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease.

The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease (2023)
Journal Article
Abhishek, A., Tedeschi, S. K., Pascart, T., Latourte, A., Dalbeth, N., Neogi, T., …Choi, H. K. (2023). The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease. Arthritis and Rheumatology, 75(10), 1703-1713. https://doi.org/10.1002/art.42619

Objective

Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have deve... Read More about The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.

Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research (2023)
Journal Article
O'Sullivan, O., Behan, F. P., Coppack, R. J., Stocks, J., Kluzek, S., Valdes, A. M., & Bennett, A. N. (2024). Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research. BMJ Military Health, 170(4), 359-364. https://doi.org/10.1136/military-2023-002390

Within the UK Armed Forces, musculoskeletal injuries account for over half of all medical downgrades and discharges. Data from other Armed Forces show that osteoarthritis (OA), more common in military personnel, is likely to contribute to this, both... Read More about Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research.

Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players (2023)
Journal Article
Espahbodi, S., Hogervorst, E., Macnab, T. P., Thanoon, A., Fernandes, G. S., Millar, B., …Zhang, W. (2023). Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players. JAMA Network Open, 6(7), Article e2323822. https://doi.org/10.1001/jamanetworkopen.2023.23822

Importance Although professional soccer players appear to be at higher risk of neurodegenerative disease, the reason remains unknown.

Objective To examine whether heading frequency is associated with risk of cognitive impairment in retired profe... Read More about Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players.

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article
Ogliari, G., Ryg, J., Andersen-Ranberg, K., Scheel-Hincke, L. L., Collins, J. T., Cowley, A., …Masud, T. (2023). Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). European Geriatric Medicine, 14(5), 1111-1124. https://doi.org/10.1007/s41999-023-00835-5

Purpose
To investigate the longitudinal associations between pain and depressive symptoms in adults.

Methods
Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data (2023)
Journal Article
Coates, G., Clewes, P., Lohan, C., Stevenson, H., Wood, R., Tritton, T., …Walsh, D. (2023). Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data. BMJ Open, 13(7), Article e067545. https://doi.org/10.1136/bmjopen-2022-067545

Objective: Despite the prevalence of osteoarthritis (OA) in England, few studies have examined the health economic impact of chronic pain associated with OA. The aim of this study was to compare outcomes in patients with moderate-to-severe chronic pa... Read More about Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data.

Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database. (2023)
Journal Article
Swain, S., Coupland, C., Sarmanova, A., Kuo, C. F., Mallen, C., Doherty, M., & Zhang, W. (2023). Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database. British Journal of General Practice, 73(733), e615-e622. https://doi.org/10.3399/BJGP.2022.0419

Background The burden of osteoarthritis (OA) in UK primary care has not been investigated thoroughly.

Aim To estimate healthcare use and mortality in people with OA (overall and joint specific).

Design and setting A matched cohort study of adul... Read More about Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database..

Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data (2023)
Journal Article
Kamps, A., Runhaar, J., de Ridder, M. A., de Wilde, M., van der Lei, J., Zhang, W., …Bierma-Zeinstra, S. M. (2023). Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data. Arthritis Research and Therapy, 25(1), Article 114. https://doi.org/10.1186/s13075-023-03086-8

Background: Comorbidities are common in patients with osteoarthritis (OA). This study aimed to determine the association of a wide range of previously diagnosed comorbidities in adults with newly diagnosed OA compared with matched controls without OA... Read More about Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data.

“I’ve still got a job to go back to”: the importance of early vocational rehabilitation after stroke (2023)
Journal Article
Moore, N., Reeder, S., O’Keefe, S., Alves-Stein, S., Schneider, E., Moloney, K., Radford, K., & Lannin, N. A. (2024). “I’ve still got a job to go back to”: the importance of early vocational rehabilitation after stroke. Disability and Rehabilitation, 46(13), 2769-2776. https://doi.org/10.1080/09638288.2023.2230125

Purpose
Returning to work is an important goal after stroke, not only as a recovery indicator but also for facilitating independent living and improved social identity. The aim of this study was to explore the lived experiences of vocational rehabil... Read More about “I’ve still got a job to go back to”: the importance of early vocational rehabilitation after stroke.

Characterization of a Helicobacter pylori strain with high biofilm-forming ability (2023)
Journal Article
Wilkinson, D., Alsharaf, L., Thompson, S., Paulin, A., Takor, R., Zaitoun, A., …Winter, J. (2023). Characterization of a Helicobacter pylori strain with high biofilm-forming ability. Journal of Medical Microbiology, 72(6), Article 001710. https://doi.org/10.1099/jmm.0.001710

Introduction. Helicobacter pylori is highly polymorphic, and some strains are much more likely to cause disease than others. Biofilm formation can help bacteria to survive antibiotic treatment, immune attack and other stresses, promoting persistent i... Read More about Characterization of a Helicobacter pylori strain with high biofilm-forming ability.

Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study (2023)
Journal Article
Macnab, T. P., Espahbodi, S., Hogervorst, E., Thanoon, A., Fernandes, G. S., Millar, B., …Zhang, W. (2023). Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study. Sports Medicine - Open, 9, Article 43. https://doi.org/10.1186/s40798-023-00588-2

Background
Previous studies based on death certificates have found professional soccer players were more likely to die with neurodegenerative diseases, including dementia. Therefore, this study aimed to investigate whether retired professional male... Read More about Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study.

"Crack on": a qualitative study of care home managers experiences and responses to system-led setbacks during the crisis of the COVID- 19 Pandemic in England (2023)
Journal Article
Marshall, F., Gordon, A. L., Gladman, J. R., & Bishop, S. (2023). "Crack on": a qualitative study of care home managers experiences and responses to system-led setbacks during the crisis of the COVID- 19 Pandemic in England. European Geriatric Medicine, 14(4), 811-821. https://doi.org/10.1007/s41999-023-00804-y

Objectives: To explore care home managers’ experiences of systems working with various organisations, including statutory, third sector and private, during the second wave of the COVID-19 pandemic from Sept 2020 to April 2021 Design: An exploratory q... Read More about "Crack on": a qualitative study of care home managers experiences and responses to system-led setbacks during the crisis of the COVID- 19 Pandemic in England.

Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts (2023)
Journal Article
Neves, R., DeDiosPerez, B., Panek, R., Jagani, S., Wilne, S., Mahendra Bhatt, J., …Dineen, R. A. (2023). Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts. Cancer Medicine, 12(13), 14663-14673. https://doi.org/10.1002/cam4.6075

Background/Objectives: Ataxia telangiectasia (A‐T) is a multiorgan disorder with increased vulnerability to cancer. Despite this increased cancer risk, there are no widely accepted guidelines for cancer surveillance in people affected by A‐T. We aime... Read More about Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts.

Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting (2023)
Journal Article
Thomas, S., Machuel, P., Foubert, J., Nafilyan, V., Bannister, N., Colvin, H., …Gordon, A. (2023). Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting. BMJ Open, 13(5), Article e067786. https://doi.org/10.1136/bmjopen-2022-067786

INTRODUCTION: Older people were at particular risk of morbidity and mortality during COVID-19. Consequently, they experienced formal (externally imposed) and informal (self-imposed) periods of social isolation and quarantine. This is hypothesised to... Read More about Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting.

The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review (2023)
Journal Article
De Dios Perez, B., McQueen, J., Craven, K., Radford, K., Blake, H., Smith, B., …Holmes, J. (2023). The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review. British Journal of Occupational Therapy, 86(7), 467-481. https://doi.org/10.1177/03080226231170996

Introduction: People with long-term conditions or recovering from serious injuries can struggle to return to work. The evidence for occupational therapy supporting return to work is limited. We aimed to identify and explain how occupational therapy i... Read More about The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review.

‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study (2023)
Journal Article
Mousoulis, C., Karantana, A., Trickett, R. W., Thomas, K. S., & Leighton, P. (2023). ‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study. BMJ Open, 13(5), Article e065185. https://doi.org/10.1136/bmjopen-2022-065185

Objectives: To (1) generate detailed, person-centred data about the experience of finger injury and treatment and (2) understand the patients’ perspectives of research involvement with a view to informing better designed future studies in hand injury... Read More about ‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study.

The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort (2023)
Journal Article
Chaplin, W. J., McWilliams, D. F., Millar, B. S., Gladman, J. R. F., & Walsh, D. A. (2023). The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort. BMC Geriatrics, 23(1), Article 273. https://doi.org/10.1186/s12877-023-03949-4

Background: Pain and frailty are associated, but this relationship is insufficiently understood. We aimed to test whether there is a unidirectional or bidirectional relationship between joint pain and frailty. Methods: Data were from Investigating Mu... Read More about The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort.