Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial
(2024)
Journal Article
Hirschfield, G. M., Arndtz, K., Kirkham, A., Chen, Y.-Y., Fox, R., Rowe, A., Douglas-Pugh, J., Thorburn, D., Barnes, E., Aithal, G. P., Hull, D., Bhandal, K., Olsen, K., Woodward, P., Lax, S., Newsome, P., Smith, D. J., Kallio, A., Adams, D. H., Homer, V., & Weston, C. J. (2024). Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial. Hepatology Communications, 8(5), Article e0426. https://doi.org/10.1097/hc9.0000000000000426
Background: Primary sclerosing cholangitis is a progressive inflammatory liver disease characterized by biliary and liver fibrosis. Vascular adhesion protein-1 (VAP-1) is important in the inflammatory process driving liver fibrosis. We evaluated th... Read More about Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial.