All Outputs (381)

Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting (2023)
Journal Article
Thomas, S., Machuel, P., Foubert, J., Nafilyan, V., Bannister, N., Colvin, H., …Gordon, A. (2023). Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting. BMJ Open, 13(5), Article e067786. https://doi.org/10.1136/bmjopen-2022-067786

INTRODUCTION: Older people were at particular risk of morbidity and mortality during COVID-19. Consequently, they experienced formal (externally imposed) and informal (self-imposed) periods of social isolation and quarantine. This is hypothesised to... Read More about Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting.

Accuracy of artificial intelligence software for CT angiography in stroke (2023)
Journal Article
Mair, G., White, P., Bath, P. M., Muir, K., Martin, C., Dye, D., …for the RITeS Collaboration. (2023). Accuracy of artificial intelligence software for CT angiography in stroke. Annals of Clinical and Translational Neurology, 10(7), 1072-1082. https://doi.org/10.1002/acn3.51790

Objective: Software developed using artificial intelligence may automatically identify arterial occlusion and provide collateral vessel scoring on CT angiography (CTA) performed acutely for ischemic stroke. We aimed to assess the diagnostic accuracy... Read More about Accuracy of artificial intelligence software for CT angiography in stroke.

The impact of sleep difficulties in children with attention deficit hyperactivity disorder on the family: a thematic analysis (2023)
Journal Article
French, B., Quain, E., Kilgariff, J., Lockwood, J., & Daley, D. (2023). The impact of sleep difficulties in children with attention deficit hyperactivity disorder on the family: a thematic analysis. Journal of Clinical Sleep Medicine, 19(10), 1735-1741. https://doi.org/10.5664/jcsm.10662

Background. Attention Deficit Hyperactivity Disorder (ADHD) is a complex but common neurodevelopmental condition characterised by symptoms of inattention, hyperactivity and impulsivity associated with a significant level of academic, social and funct... Read More about The impact of sleep difficulties in children with attention deficit hyperactivity disorder on the family: a thematic analysis.

What Happens When We Hear? (2023)
Journal Article
Sumner, C. J., Akeroyd, M. A., Sollini, J., & Hart, C. (in press). What Happens When We Hear?. Frontiers for Young Minds, 11, 1072364. https://doi.org/10.3389/frym.2023.1072364

What happens when we hear? Where does the sound go when it enters our ears? Our ears sense the vibrations of the air and convert them into electrical signals the brain can process. But that is only the start. The brain uses tens of thousands of nerve... Read More about What Happens When We Hear?.

ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK. (2023)
Journal Article
Jacobs, B. M., Schalk, L., Dunne, A., Scalfari, A., Nandoskar, A., Gran, B., …Dobson, R. (2023). ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK. BMJ Open, 13(5), Article e071656. https://doi.org/10.1136/bmjopen-2023-071656

Purpose Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The gene... Read More about ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK..

The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review (2023)
Journal Article
De Dios Perez, B., McQueen, J., Craven, K., Radford, K., Blake, H., Smith, B., …Holmes, J. (2023). The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review. British Journal of Occupational Therapy, 86(7), 467-481. https://doi.org/10.1177/03080226231170996

Introduction: People with long-term conditions or recovering from serious injuries can struggle to return to work. The evidence for occupational therapy supporting return to work is limited. We aimed to identify and explain how occupational therapy i... Read More about The effectiveness of occupational therapy supporting return to work for people who sustain serious injuries or develop long-term (physical or mental) health conditions: A systematic review.

Online peer support: views and experiences of people with young onset dementia (YOD) (2023)
Journal Article
Gerritzen, E. V., McDermott, O., & Orrell, M. (2023). Online peer support: views and experiences of people with young onset dementia (YOD). Aging and Mental Health, 27(12), 2386-2394. https://doi.org/10.1080/13607863.2023.2205833

Objectives: This study explores (1) which platforms people with YOD use for online peer support, (2) reasons for using or not using online peer support, and (3) how to optimise potential benefits and accessibility. Methods: A mixed-methods online sur... Read More about Online peer support: views and experiences of people with young onset dementia (YOD).

A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder (2023)
Journal Article
Morera Maiquez, B., Morera Maiquez, B., Smith, C., Dyke, K., Chou, C.-P., Kasbia, B., …Jackson, S. R. (2023). A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder. Journal of Neuropsychology, 17(3), 540-563. https://doi.org/10.1111/jnp.12313

Tourette syndrome (TS) and chronic tic disorder (CTD) are neurological disorders of childhood onset characterized by the occurrence of tics; repetitive, purposeless, movements or vocalizations of short duration which can occur many times throughout a... Read More about A double-blind, sham-controlled, trial of home-administered rhythmic 10-Hz median nerve stimulation for the reduction of tics, and suppression of the urge-to-tic, in individuals with Tourette syndrome and chronic tic disorder.

Person-attuned musical interactions (PAMI) in dementia care. Complex intervention research for constructing a training manual (2023)
Journal Article
Ridder, H. M., Krøier, J. K., Anderson-Ingstrup, J., & McDermott, O. (2023). Person-attuned musical interactions (PAMI) in dementia care. Complex intervention research for constructing a training manual. Frontiers in Medicine, 10, Article 1160588. https://doi.org/10.3389/fmed.2023.1160588

Introduction: Music is of vital importance for cognition, human care, and the formation of social communities throughout life. Dementia is a neurocognitive disorder that affects cognitive domains, and in late-stage dementia, care is needed in all asp... Read More about Person-attuned musical interactions (PAMI) in dementia care. Complex intervention research for constructing a training manual.

Evaluation of Endothelial Progenitor Cell Characteristics as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke (2023)
Journal Article
Rakkar, K., Othman, O. A., Sprigg, N., Bath, P. M., & Bayraktutan, U. (2023). Evaluation of Endothelial Progenitor Cell Characteristics as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke. Stem Cell Reviews and Reports, 19(6), 1856-1869. https://doi.org/10.1007/s12015-023-10544-y

Ageing impairs endothelial function and predisposes the person to ischaemic stroke (IS). Endothelial progenitor cells (EPCs) repair endothelial damage and induce post-ischaemic neovascularisation. Given the prevalence of IS in older population, this... Read More about Evaluation of Endothelial Progenitor Cell Characteristics as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke.

Exploring factors influencing willingness of older adults to use assistive technologies: evidence from the cognitive function and ageing study II (2023)
Journal Article
Begde, A., Jain, M., Goodwin, M., Brayne, C., Barnes, L., Brooks, R., …Hogervorst, E. (2024). Exploring factors influencing willingness of older adults to use assistive technologies: evidence from the cognitive function and ageing study II. Information, Communication and Society, 27(2), 368-385. https://doi.org/10.1080/1369118X.2023.2205915

Technology is widely promoted as a solution to greater independence and better health for the rapidly growing UK older population. If this is to be realised, we need to understand barriers and facilitators to uptake and investigate who wants this tec... Read More about Exploring factors influencing willingness of older adults to use assistive technologies: evidence from the cognitive function and ageing study II.

We need timely access to mental health data: implications of the Goldacre review (2023)
Journal Article
Astle, D. E., Moore, A., Marryat, L., Viding, E., Mansfield, K. L., Fazel, M., …Ford, T. J. (2023). We need timely access to mental health data: implications of the Goldacre review. Lancet Psychiatry, 10(4), 242-244. https://doi.org/10.1016/S2215-0366%2823%2900030-5

The Goldacre review, published in April, 2022, 1 is a landmark evaluation of the use, availability, and safety of National Health Service (NHS) data across all four nations of the UK. The review underscores the necessary role of data in driving healt... Read More about We need timely access to mental health data: implications of the Goldacre review.

Disproportionate Expression of ATM in Cerebellar Cortex During Human Neurodevelopment (2023)
Journal Article
Deacon, S., Dalleywater, W., Peat, C., Paine, S. M., & Dineen, R. A. (2024). Disproportionate Expression of ATM in Cerebellar Cortex During Human Neurodevelopment. Cerebellum, 23(2), 502-511. https://doi.org/10.1007/s12311-023-01560-2

Cerebellar neurodegeneration is a classical feature of ataxia telangiectasia (A-T), an autosomal recessive condition caused by loss-of-function mutation of the ATM gene, a gene with multiple regulatory functions. The increased vulnerability of cerebe... Read More about Disproportionate Expression of ATM in Cerebellar Cortex During Human Neurodevelopment.

Endovascular Thrombectomy Versus Best Medical Management Beyond 24 Hours From Last Known Well in Acute Ischemic Stroke Due to Large Vessel Occlusion (2023)
Journal Article
Dhillon, P. S., Butt, W., Jovin, T. G., Podlasek, A., McConachie, N., Lenthall, R., …England, T. J. (2023). Endovascular Thrombectomy Versus Best Medical Management Beyond 24 Hours From Last Known Well in Acute Ischemic Stroke Due to Large Vessel Occlusion. Stroke: Vascular and Interventional Neurology, 3(5), Article e000790. https://doi.org/10.1161/svin.122.000790

BACKGROUND
The safety and efficacy of endovascular thrombectomy (EVT) in patients with acute ischemic stroke due to large vessel occlusion presenting beyond 24 hours from last known well (LKW) remains undetermined.

METHODS
In this single center... Read More about Endovascular Thrombectomy Versus Best Medical Management Beyond 24 Hours From Last Known Well in Acute Ischemic Stroke Due to Large Vessel Occlusion.

Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial (2023)
Journal Article
Pan, Y., Meng, X., Yuan, B., Johnston, S. C., Li, H., Bath, P. M., …Wang, Y. (2023). Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial. Lancet Neurology, 22(6), 485-493. https://doi.org/10.1016/s1474-4422%2823%2900113-8

Background
Aspirin is recommended for secondary stroke prevention in patients with moderate-to-severe ischaemic stroke but can lead to gastrointestinal intolerance and bleeding. Indobufen is used as an alternative antiplatelet agent in some countrie... Read More about Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial.

Comparison Between In‐Hospital and Community‐Onset Stroke Treated With Endovascular Thrombectomy: A Propensity Score–Matched Cohort Study (2023)
Journal Article
Dhillon, P. S., Soo, E., Butt, W., Nguyen, T. N., Barrett, E., Podlasek, A., …England, T. J. (2023). Comparison Between In‐Hospital and Community‐Onset Stroke Treated With Endovascular Thrombectomy: A Propensity Score–Matched Cohort Study. Stroke: Vascular and Interventional Neurology, 3(4), Article e000816. https://doi.org/10.1161/svin.122.000816

Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study (2023)
Journal Article
Andrews, J. A., Craven, M. P., Guo, B., Weyer, J., Lees, S., Zormpas, S. I., …RADAR-CNS Consortium. (2023). Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study. JMIR Neurotechnology, 2, Article e41439. https://doi.org/10.2196/41439

Background: Multiple sclerosis (MS), epilepsy, and depression are chronic central nervous system conditions in which remote measurement technology (RMT) may offer benefits compared with usual assessment. We previously worked with clinicians, patients... Read More about Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study.

The impact of tinnitus on adult cochlear implant recipients: A mixed-method approach (2023)
Journal Article
Assouly, K. K., Shabbir, M., van Dijk, B., Hoare, D. J., Akeroyd, M. A., Stokroos, R. J., …Smit, A. L. (2023). The impact of tinnitus on adult cochlear implant recipients: A mixed-method approach. PLoS ONE, 18(4), Article e0284719. https://doi.org/10.1371/journal.pone.0284719

Background
Tinnitus is a common problem in patients with a cochlear implant (CI). Between 4% and 25% of CI recipients experience a moderate to severe tinnitus handicap. However, apart from handicap scores, little is known about the real-life impact... Read More about The impact of tinnitus on adult cochlear implant recipients: A mixed-method approach.

Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff (2023)
Journal Article
Walker, K., Yates, J., Dening, T., Völlm, B., Tomlin, J., & Griffiths, C. (2023). Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff. International Journal of Qualitative Studies on Health and Well-being, 18(1), Article 2202978. https://doi.org/10.1080/17482631.2023.2202978

Purpose
There is a lack of research informing service requirements for older (aged≥55 years) forensic mental health patients. The aim of this research was to increase knowledge about older forensic mental health patients’ quality of life, wellbeing,... Read More about Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff.

Patient perceptions of cognitive screening in adult audiology services: A qualitative exploration (2023)
Journal Article
Broome, E. E., Tannirandorn, P., Straus, J., Beale, P., Heffernan, E., Dening, T., & Henshaw, H. (2023). Patient perceptions of cognitive screening in adult audiology services: A qualitative exploration. Frontiers in Neurology, 14, Article 1143128. https://doi.org/10.3389/fneur.2023.1143128

Introduction: Both hearing loss and dementia are extremely pervasive, especially amongst older adults. As hearing loss and dementia have common symptoms, misdiagnosis can be common, and failure to address hearing loss for people with dementia could a... Read More about Patient perceptions of cognitive screening in adult audiology services: A qualitative exploration.