All Outputs (386)

Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months (2023)
Journal Article
Nixon, N., Guo, B., Kaylor-Hughes, C., Simpson, S., Garland, A., Dalgleish, T., & Morriss, R. (2024). Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months. Journal of Affective Disorders, 345, 70-77. https://doi.org/10.1016/j.jad.2023.10.105

Background: Despite the known health costs of persistent depression, there is no established service framework for the treatment of this disorder and a lack of long-term outcome data to inform commissioning. To address this gap, we report the long-te... Read More about Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task. Trends in Hearing, Article 27. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task. Trends in Hearing, 27, Article 23312165231196520. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference Contribution
Christie, H. L., Atefi, G. L., Craven, M. P., Orrell, M., & de Vugt, M. E. (2023, October). Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist. Poster presented at 33rd Alzheimer Europe Conference, Helsinki, Finland

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers

Problem: Few evidence-based eHealth interventions are implemented in practice

Solution :
Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article
Kalvala, J., Chong, L., Chadborn, N., & Ojha, S. (2023). Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review. BMJ Paediatrics Open, 7(1), Article e002066. https://doi.org/10.1136/bmjpo-2023-002066

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

Social anxiety is more likely to influence reputation management decisions than autistic traits (2023)
Journal Article
Dubey, I., Groom, M., Tahir, A., & Hamilton, A. (2024). Social anxiety is more likely to influence reputation management decisions than autistic traits. Autism Research, 17(1), 78-88. https://doi.org/10.1002/aur.3040

People manage their social reputation by selectively sharing achievements, thereby shaping the way others think about them. Autistic traits and social anxiety may have opposing impacts on reputation management. This study aimed to identify the influe... Read More about Social anxiety is more likely to influence reputation management decisions than autistic traits.

The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills (2023)
Journal Article
Kubota, M., Hadley, L. V., Schäffner, S., Könend, T., Meaneye, J.-A., Moreyf, C. C., …Chevalier, N. (2023). The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills. Developmental Psychology, 59(11), 2002-2020. https://doi.org/10.1037/dev0001626

The current study investigated the effects of metacognitive and executive function (EF) training on childhood EF (inhibition, working memory [WM], cognitive flexibility, and proactive/reactive control) and academic skills (reading, reasoning, and mat... Read More about The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills.

Understanding and exploring the cost of poor mental health at work for organisations and society (2023)
Book Chapter
Hassard, J., Thomson, L., & Blake, H. (2024). Understanding and exploring the cost of poor mental health at work for organisations and society. In A. Day, & C. L. Cooper (Eds.), The Routledge Companion to Mental Health at Work. Routledge

This chapter explores the cost of mental health at work from an employer and societal perspective. We aim to present and reflect on the available evidence of the economic burden and human cost posed by poor mental health at work. A fuller understandi... Read More about Understanding and exploring the cost of poor mental health at work for organisations and society.

CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism (2023)
Journal Article
Puzniak, R. J., Prabhakaran, G. T., McLean, R. J., Stober, S., Ather, S., Proudlock, F. A., …Hoffmann, M. B. (2023). CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism. Investigative Ophthalmology & Visual Science, 64(13), Article 14. https://doi.org/10.1167/iovs.64.13.14

Purpose: Albinism is a congenital disorder affecting pigmentation levels, structure, and function of the visual system. The identification of anatomical changes typical for people with albinism (PWA), such as optic chiasm malformations, could become... Read More about CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article
Bellato, A., Hall, C. L., Groom, M. J., Simonoff, E., Thapar, A., Hollis, C., & Cortese, S. (2024). Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, 65(6), 845-861. https://doi.org/10.1111/jcpp.13901

Background
Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

Management standards and burnout among surgeons in the United Kingdom (2023)
Journal Article
Houdmont, J., Hassard, J., Daliya, P., Adiamah, A., Theophilidou, E., Lobo, D., & East Midlands Surgical Academic Network (EMSAN) Burnout Study Group, E. M. S. A. N. (. B. S. G. (2023). Management standards and burnout among surgeons in the United Kingdom. Occupational Medicine, 73(8), 484-491. https://doi.org/10.1093/occmed/kqad102

Background
Burnout arising from chronic work-related stress is endemic among surgeons in the UK. Identification of contributory and modifiable psychosocial work characteristics could inform risk reduction activities.

Aims
We aimed to assess th... Read More about Management standards and burnout among surgeons in the United Kingdom.

Transient elastography and video recovery narrative access to support recovery from alcohol misuse: development of a novel intervention for use in community alcohol treatment services (2023)
Journal Article
Rennick-Egglestone, S., Subhani, M., Knight, H., Jones, K. A., Hutton, C., Jackson, T., …Ryder, S. (2023). Transient elastography and video recovery narrative access to support recovery from alcohol misuse: development of a novel intervention for use in community alcohol treatment services. JMIR Formative Research, 7, Article e47109. https://doi.org/10.2196/47109

Background: Mortality from alcohol-related liver disease has risen significantly for three decades. Transient elastography (TE) is a non-invasive test providing a numerical marker of liver disease. Preliminary evidence suggests that receiving TE can... Read More about Transient elastography and video recovery narrative access to support recovery from alcohol misuse: development of a novel intervention for use in community alcohol treatment services.

Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial (2023)
Preprint / Working Paper
Khan, K., Hall, C. L., Babbage, C., Dodzo, S., Greenhalgh, C., Lucassen, M., Merry, S., Sayal, K., Sprange, K., Stasiak, K., Tench, C. R., Townsend, E., Stallard, P., & Hollis, C. Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial

Background:

A serious game (SPARX), developed in New Zealand and incorporating cognitive behavioural therapy (CBT) principles, has been shown to help reduce symptoms of depression and anxiety in adolescents with mild to moderate depression. Howev... Read More about Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial.

The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults (2023)
Journal Article
Atkin, C., Stacey, J. E., Roberts, K. L., Allen, H. A., Henshaw, H., & Badham, S. P. (2023). The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults. Scientific Reports, 13, Article 16575. https://doi.org/10.1038/s41598-023-41791-1

Studies using simple low-level stimuli show that multisensory stimuli lead to greater improvements in processing speed for older adults than young adults. However, there is insufficient evidence to explain how these benefits influence performance for... Read More about The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults.

Unified Surface and Volumetric Inference on Functional Imaging Data (2023)
Presentation / Conference Contribution
Kirk, T. F., Craig, M. S., & Chappell, M. A. (2023). Unified Surface and Volumetric Inference on Functional Imaging Data. In J. Duncan, H. Greenspan, A. Madabhushi, P. Mousavi, S. Salcudean, T. Syeda-Mahmood, & R. Taylor (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2023: 26th International Conference, Vancouver, BC, Canada, October 8–12, 2023, Proceedings, Part VIII (399-408). https://doi.org/10.1007/978-3-031-43993-3_39

Surface-based analysis methods for functional imaging data have been shown to offer substantial benefits for the study of the human cortex, namely in the localisation of functional areas and the establishment of inter-subject correspondence. A new ap... Read More about Unified Surface and Volumetric Inference on Functional Imaging Data.

Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study (2023)
Journal Article
Kai, J., Dutton, B., Vinogradova, Y., Hilken, N., Gupta, J., & Daniels, J. (2023). Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study. Health Technology Assessment, 27(17), https://doi.org/10.3310/jhsw0174

Background: Heavy menstrual bleeding is a common problem that can significantly affect women’s lives until menopause. There is a lack of evidence on longer-term outcomes after seeking health care and treatment for heavy menstrual bleeding. Objectives... Read More about Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study.

The assessment of dysphagia after stroke: state of the art and future directions (2023)
Journal Article
Labeit, B., Michou, E., Hamdy, S., Trapl-Grundschober, M., Suntrup-Krueger, S., Muhle, P., …Dziewas, R. (2023). The assessment of dysphagia after stroke: state of the art and future directions. Lancet Neurology, 22(9), 858-870. https://doi.org/10.1016/S1474-4422%2823%2900153-9

Dysphagia is a major complication following an acute stroke that affects the majority of patients. Clinically, dysphagia after stroke is associated with increased risk of aspiration pneumonia, malnutrition, mortality, and other adverse functional out... Read More about The assessment of dysphagia after stroke: state of the art and future directions.

Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials (2023)
Journal Article
Krishnan, K., Campos, P. B., Nguyen, T. N., Tan, C. W., Chan, S. L., Appleton, J. P., …Bath, P. M. (2023). Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials. Frontiers in Stroke, 2, Article 1256664. https://doi.org/10.3389/fstro.2023.1256664

Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical tr... Read More about Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials.

Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. (2023)
Journal Article
Murray, A. J., Humpston, C. S., Wilson, M., Rogers, J. C., Zia Ul Haq Katshu, M., Liddle, P. F., & Upthegrove, R. (2024). Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. Brain, Behavior, and Immunity, 115, 3-12. https://doi.org/10.1016/j.bbi.2023.09.017

Oxidative stress may contribute to declining course and poor outcomes in psychosis. However, in vivo Magnetic Resonance Spectroscopy studies yield disparate results due to clinical stage, sample demographics, neuroanatomical focus, sample size, and a... Read More about Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis..

Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror (2023)
Journal Article
Dowthwaite, L., Reyes Cruz, G., Pena, A. R., Pepper, C., Jäger, N., Barnard, P., …Benford, S. (2023). Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror. Healthcare, 11(19), Article 2608. https://doi.org/10.3390/healthcare11192608

The home is becoming a key location for healthcare delivery, including the use of technology driven by autonomous systems (AS) to monitor and support healthcare plans. Using the example of a smart mirror, this paper describes the outcomes of focus gr... Read More about Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror.