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All Outputs (44)

Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT) (2014)
Journal Article
Weng, S. F., Kai, J., Neil, H. A., Humphries, S. E., & Qureshi, N. (2015). Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT). Atherosclerosis, 238(2), https://doi.org/10.1016/j.atherosclerosis.2014.12.034

Objective: Heterozygous familial hypercholesterolaemia (FH) is a common autosomal dominant disorder. The vast majority of affected individuals remain undiagnosed, resulting in lost opportunities for preventing premature heart disease. Better use of r... Read More about Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT).

Implementing an Injury Prevention Briefing to aid delivery of key fire safety messages in UK children’s centres: qualitative study nested within a multi-centre randomised controlled trial (2014)
Journal Article
Beckett, K., Goodenough, T., Deave, T., Jaeckle, S., McDaid, L., Benford, P., Hayes, M., Towner, E., & Kendrick, D. (2014). Implementing an Injury Prevention Briefing to aid delivery of key fire safety messages in UK children’s centres: qualitative study nested within a multi-centre randomised controlled trial. BMC Public Health, 14(1256), https://doi.org/10.1186/1471-2458-14-1256

Background

To improve the translation of public health evidence into practice, there is a need to increase practitioner involvement in initiative development, to place greater emphasis on contextual knowledge, and to address intervention processes... Read More about Implementing an Injury Prevention Briefing to aid delivery of key fire safety messages in UK children’s centres: qualitative study nested within a multi-centre randomised controlled trial.

Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP) (2014)
Journal Article
Essex, H., Parrott, S., Wu, Q., Li, J., Cooper, S., & Coleman, T. (2014). Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP). Nicotine and Tobacco Research, https://doi.org/10.1093/ntr/ntu258

Introduction: Smoking during pregnancy is the most important, preventable cause of adverse pregnancy outcomes including miscarriage, premature birth and low birth weight, with huge financial costs to the NHS. However, there are very few published eco... Read More about Cost-effectiveness of nicotine patches for smoking cessation in pregnancy: a placebo randomised controlled trial (SNAP).

Exercise for reducing fear of falling in older people living in the community (2014)
Journal Article
Kendrick, D., Kumar, A., Carpenter, H., Rixt Zijlstra, G., Skelton, D. A., Cooke, J. R., Stevens, Z., Belcher, C., Haworth, D., Gawler, S. J., Gage, H., Masud, T., Bowling, A., Pearl, M., Morris, R. W., Iliffe, S., & Delbaere, K. (2014). Exercise for reducing fear of falling in older people living in the community. Cochrane Database of Systematic Reviews, 11, Article CD009848. https://doi.org/10.1002/14651858.CD009848.pub2

Background: Fear of falling is common in older people and associated with serious physical and psychosocial consequences. Exercise (planned, structured, repetitive and purposive physical activity aimed at improving physical fitness) may reduce fear o... Read More about Exercise for reducing fear of falling in older people living in the community.

Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence (2014)
Journal Article
Orton, S., Jones, L. L., Cooper, S., Lewis, S., & Coleman, T. (2014). Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence. PLoS ONE, 9(11), Article e112690. https://doi.org/10.1371/journal.pone.0112690

BACKGROUND: Children's exposure to secondhand smoke (SHS) has been causally linked to a number of childhood morbidities and mortalities. Over 50% of UK children whose parents are smokers are regularly exposed to SHS at home. No previous review has id... Read More about Predictors of children's secondhand smoke exposure at home: a systematic review and narrative synthesis of the evidence.

Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5 (2014)
Journal Article
Orton, E., Kendrick, D., West, J., & Tata, L. J. (2014). Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5. PLoS ONE, 9(10), Article e111631. https://doi.org/10.1371/journal.pone.0111631

BACKGROUND: Injury is a significant cause of childhood death and can result in substantial long-term disability. Injuries are more common in children from socio-economically deprived families, contributing to health inequalities between the most and... Read More about Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5.

Tools for primary care patient safety: a narrative review (2014)
Journal Article
Spencer, R., & Campbell, S. M. (2014). Tools for primary care patient safety: a narrative review. BMC Family Practice, 15, Article 166. https://doi.org/10.1186/1471-2296-15-166

Background: Patient safety in primary care is a developing field with an embryonic but evolving evidence base. This narrative review aims to identify tools that can be used by family practitioners as part of a patient safety toolkit to improve the sa... Read More about Tools for primary care patient safety: a narrative review.

A comparison of UK primary care data with other national data sources for monitoring the prevalence of smoking during pregnancy (2014)
Journal Article
Dhalwani, N. N., Tata, L. J., Coleman, T., Fiaschi, L., & Szatkowski, L. (2015). A comparison of UK primary care data with other national data sources for monitoring the prevalence of smoking during pregnancy. Journal of Public Health, 37(3), 547-554. https://doi.org/10.1093/pubmed/fdu060

Background: We aimed to assess the potential usefulness of primary care data for estimating smoking prevalence in pregnancy by comparing the primary care data estimates with those obtained from other data sources.
Methods: In The Health Improvement... Read More about A comparison of UK primary care data with other national data sources for monitoring the prevalence of smoking during pregnancy.

Breast cancer screening uptake among women from different ethnic groups in London: A population-based cohort study (2014)
Journal Article
Jack, R. H., Møller, H., Robson, T., & Davies, E. A. (2014). Breast cancer screening uptake among women from different ethnic groups in London: A population-based cohort study. BMJ Open, 4(10), Article e005586. https://doi.org/10.1136/bmjopen-2014-005586

Objective: To use newly available self-assigned ethnicity information to investigate variation in breast cancer screening uptake for women from the 16 specific ethnic groups within the broad Asian, Black and White groups that previous studies report.... Read More about Breast cancer screening uptake among women from different ethnic groups in London: A population-based cohort study.

Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial (2014)
Journal Article
Cooper, S., Taggar, J., Lewis, S., Marlow, N., Dickinson, A., Whitemore, R., & Coleman, T. (2014). Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial. Lancet Respiratory Medicine, 2(9), https://doi.org/10.1016/S2213-2600%2814%2970157-2

BACKGROUND:
The SNAP (Smoking and Nicotine in Pregnancy) trial compared nicotine replacement therapy (NRT) patches with placebo in pregnant smokers; although NRT doubled cessation rates in the first 4 weeks, by delivery no differences in maternal sm... Read More about Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial.

Effectiveness of a mobile, drop-in stop smoking service in reaching and supporting disadvantaged UK smokers to quit (2014)
Journal Article
Venn, A., Dickinson, A., Murray, R., Jones, L., Li, J., Parrott, S., & McNeill, A. (2014). Effectiveness of a mobile, drop-in stop smoking service in reaching and supporting disadvantaged UK smokers to quit. Tobacco Control, 25(1), 33-38. https://doi.org/10.1136/tobaccocontrol-2014-051760

Background: In countries where there are large disparities in smoking with persistent high rates among disadvantaged groups, there is a need to ensure that stop smoking services (SSS) reach such smokers. The primary aim of this study was to evaluate... Read More about Effectiveness of a mobile, drop-in stop smoking service in reaching and supporting disadvantaged UK smokers to quit.

The treatment and survival of patients with triple negative breast cancer in a London population (2014)
Journal Article
Pal, S., Lüchtenborg, M., Davies, E. A., & Jack, R. H. (2014). The treatment and survival of patients with triple negative breast cancer in a London population. SpringerPlus, 3(1), Article 553. https://doi.org/10.1186/2193-1801-3-553

© 2014, Pal et al.; licensee Springer. Purpose: Triple negative breast cancer (TNBC) constitutes 10-15% of female breast cancers, and clinical guidelines recommend treatment with chemotherapy and surgery. We examined the recorded treatment and surviv... Read More about The treatment and survival of patients with triple negative breast cancer in a London population.

Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data (2014)
Journal Article
Dhalwani, N. N., Szatkowski, L., Coleman, T., Fiaschi, L., & Tata, L. J. (2014). Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data. British Journal of General Practice, Article e554-e560. https://doi.org/10.3399/bjgp14X681361

Background Licensing arrangements for nicotine replacement therapy (NRT) in the UK were broadened in 2005 to allow prescribing to pregnant smokers. However, estimates of NRT prescribing in pregnant females in the UK are currently lacking.


Aim To... Read More about Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data.

The survival of patients with high grade glioma from different ethnic groups in South East England (2014)
Journal Article
Ratneswaren, T., Jack, R. M., Tataru, D., & Davies, E. A. (2014). The survival of patients with high grade glioma from different ethnic groups in South East England. Journal of Neuro-Oncology, 120(3), 531-536. https://doi.org/10.1007/s11060-014-1582-3

© 2014, Springer Science+Business Media New York. Studies in the United States (US) have reported varying treatment and survival for patients with high grade glioma from different ethnic groups. This study investigates for the first time whether diff... Read More about The survival of patients with high grade glioma from different ethnic groups in South East England.

The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation (2014)
Journal Article
Cooper, S., Lewis, S., Thornton, J., Marlow, N., Watts, K., Britton, J., Grainge, M. J., Taggar, J., Essex, H., Parrott, S., Dickinson, A., Whitemore, R., & Coleman, T. (2014). The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation. Health Technology Assessment, 18(54), 1-128. https://doi.org/10.3310/hta18540

Background: Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would in... Read More about The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation.

Multicentre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care (2014)
Journal Article
Iliffe, S., Kendrick, D., Morris, R., Masud, T., Gage, H., Skelton, D., Dinan, S., Bowling, A., Griffin, M., Haworth, D., Swanwick, G., Carpenter, H., Kumar, A., Stevens, Z., Gawler, S., Barlow, C., Cooke, J., & Belcher, C. (2014). Multicentre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care. Health Technology Assessment, 18(49), https://doi.org/10.3310/hta18490

Background: Regular physical activity (PA) reduces the risk of falls and hip fractures, and mortality from all causes. However, PA levels are low in the older population and previous intervention studies have demonstrated only modest, short-term impr... Read More about Multicentre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care.

The Optimal Study: describing the key components of optimal health care delivery to UK care home residents: a research protocol (2014)
Journal Article
Gordon, A. L., Goodman, C., Dening, T., Davies, S., Gladman, J. R., Bell, B. G., Zubair, M., Handley, M. J., Meyer, J., Bowman, C., Gage, H., Iliffe, S. R., Martin, F. C., Schneider, J., & Victor, C. (2014). The Optimal Study: describing the key components of optimal health care delivery to UK care home residents: a research protocol. Journal of the American Medical Directors Association, 15(9), https://doi.org/10.1016/j.jamda.2014.06.011

Long term institutional care in the UK is provided by care homes. Residents have prevalent cognitive impairment and disability, have multiple diagnoses and are subject to polypharmacy. Prevailing models of healthcare provision - ad hoc, reactive and... Read More about The Optimal Study: describing the key components of optimal health care delivery to UK care home residents: a research protocol.

Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores (2014)
Journal Article
Hippisley-Cox, J., & Coupland, C. (2014). Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores. BMJ, 349, Article g4606. https://doi.org/10.1136/bmj.g4606

Objective: To develop and validate risk algorithms (QBleed) for estimating the absolute risk of upper gastrointestinal and intracranial bleed for patients with and without anticoagulation aged 21-99 years in primary care.

Design: Open cohort study... Read More about Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores.

Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial (2014)
Journal Article
Lindson-Hawley, N., Coleman, T., Docherty, G., Hajek, P., Lewis, S., Lycett, D., McEwen, A., McRobbie, H., Munafo, M. R., Parrott, S., & Aveyard, P. (2014). Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial. Trials, 15(296), https://doi.org/10.1186/1745-6215-15-296

Background: The use of nicotine replacement therapy before quitting smoking is called nicotine preloading. Standard smoking cessation protocols suggest commencing nicotine replacement therapy only on the first day of quitting smoking (quit day) aimin... Read More about Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial.