All Outputs (12)

Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels (2007)
Journal Article

Environmental factors (e.g. stress, exercise, enrichment) are thought to play a role in the development of Alzheimer's disease later in life. We investigated the influence of repeated novel cage exposure on the development of early Alzheimer's-like p... Read More about Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels.

Should data monitoring committees assess efficacy when considering safety in trails in acute stroke? (2007)
Journal Article

The primary role of a trials Data Monitoring Committee (DMC) is to ensure the safety of enrolled patients. In stroke trials, safety is monitored typically by comparing death and stroke specific events between treatment groups. DMCs may also have the... Read More about Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?.

Multiple sclerosis findings in the spinal cord (2007)
Journal Article

Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2007)
Journal Article

Introduction: Female sex is predictive of poor functional outcome in stroke, even after correction for prognostic factors. Poor quality of life (QoL) is observed in stroke survivors, with lower scores seen in the most disabled patients. We used data... Read More about Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).

High blood pressure in acute stroke: to treat or not to treat (2007)
Journal Article

The Virtual International Stroke Trials Archive (2007)
Journal Article

Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for r... Read More about The Virtual International Stroke Trials Archive.

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials (2007)
Journal Article

Background and Purpose—Most large acute stroke trials have been neutral. Functional outcome is usually analyzed usinga yes or no answer, eg, death or dependency versus independence. We assessed which statistical approaches are mostefficient in analyz... Read More about Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials.

Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2007)
Journal Article

Introduction: Baseline severity and clinical stroke syndrome (Oxford Community Stroke Project, OCSP) classification are predictors of outcome in stroke. We used data from the ‘Tinzaparin in Acute Ischaemic Stroke Trial’ (TAIST) to assess the relation... Read More about Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).

Is there a link between aspirin therapy and stroke severity (2007)
Journal Article

Published by: http://npg.nature.com/

Unruptured arteriovenous malformations of the brain (2007)
Journal Article

Unruptured, asymptomatic arteriovenous malformations (AVMs) lurk in the brains of approximately one person in every thousand; their prevalence, based on four studies of magnetic resonance imaging (MRI) of 7,359 people without brain disorders, 1-4 was... Read More about Unruptured arteriovenous malformations of the brain.

Colony stimulating factors (blood growth factors) are promising but unproven for treating stroke (2007)
Journal Article

Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333) (2007)
Journal Article

Amphetamine enhances recovery after experimental ischaemia and has shown promise in small clinical trials when combined with motor or sensory stimulation. Amphetamine, a sympathomimetic, might have haemodynamic effects in stroke patients, although li... Read More about Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333).