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All Outputs (824)

Researching the lived experiences of cancer patients with malignant fungating wounds (2015)
Journal Article
Rowan, S., Moffatt, C., & Olden, A. (2015). Researching the lived experiences of cancer patients with malignant fungating wounds. International Journal of Palliative Nursing, 21(12), https://doi.org/10.12968/ijpn.2015.21.12.579

Background: Researching the experiences of terminally ill patients with disfiguring wounds is likely to be a challenge anywhere, and this investigation came face-to-face with different attitudes on the part of both patients and nurses and doctors in... Read More about Researching the lived experiences of cancer patients with malignant fungating wounds.

Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis (2015)
Journal Article
Piasecki, M., Ireland, A., Stashuk, D., Hamilton-Wright, A., Jones, D., & McPhee, J. (2016). Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis. Journal of Physiology, 594(16), 4525-4536. https://doi.org/10.1113/jp271087

The anterior thigh muscles are particularly susceptible to muscle loss and weakness during ageing, although how this is associated with changes to neuromuscular structure and function in terms of motor unit (MU) number, size and MU potential (MUP) st... Read More about Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis.

Urine tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Guo, B., Takwoingi, Y., Pennant, M., Wisniewski, S., Deeks, J. J., …Alldred, S. K. (2015). Urine tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD011984

Background

Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two. It is the commonest congenital cause of mental disability and also lea... Read More about Urine tests for Down's syndrome screening.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring (2015)
Journal Article
Gardiner, S. M., Gardner, D. S., Elmes, M., & Gray, C. (2016). Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring. British Journal of Nutrition, 115(4), 594-604. https://doi.org/10.1017/S0007114515004936

© Copyright 2015 The Authors. The Western diet is typically high in salt and fructose, which have pressor activity. Maternal diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt and fructose may influence c... Read More about Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

Supporting adherence for people starting a new medication for a long-term condition through community pharmacies: a pragmatic randomised controlled trial of the New Medicine Service (2015)
Journal Article
Elliott, R. A., Boyd, M. J., Salema, N.-E., Davies, J., Barber, N., Mehta, R. L., …Craig, C. (2016). Supporting adherence for people starting a new medication for a long-term condition through community pharmacies: a pragmatic randomised controlled trial of the New Medicine Service. BMJ Quality and Safety, 25(10), 747-758. https://doi.org/10.1136/bmjqs-2015-004400

Objective: To examine the effectiveness of the New Medicine Service (NMS), a national community pharmacy service to support medicines-taking in people starting a new medicine for a long-term condition, compared with normal practice.

Methods: Pragm... Read More about Supporting adherence for people starting a new medication for a long-term condition through community pharmacies: a pragmatic randomised controlled trial of the New Medicine Service.

An automated quasi-continuous capillary refill timing device (2015)
Journal Article
Blaxter, L., Morris, D. E., Crowe, J. A., Henry, C., Hill, S. J., Sharkey, D., …Hayes-Gill, B. R. (in press). An automated quasi-continuous capillary refill timing device. Physiological Measurement, 37(1), https://doi.org/10.1088/0967-3334/37/1/83

Capillary refill time (CRT) is a simple means of cardiovascular assessment which is widely used in clinical care. Currently, CRT is measured through manual assessment of the time taken for skin tone to return to normal colour following blanching of t... Read More about An automated quasi-continuous capillary refill timing device.

Inter-rater reliability of the AFTD-pitting test among elderly patients in a long-term medical facility (2015)
Journal Article
Dai, M., Sugama, J., Tsuchiya, S., Sato, A., Matsumoto, M., Iuchi, T., …Moffatt, C. J. (2015). Inter-rater reliability of the AFTD-pitting test among elderly patients in a long-term medical facility. https://doi.org/10.15010/LRAP.2015.06.27.02

BACKGROUND and AIM: The pitting test has been reported in various methods as a standard for evaluating chronic oedema, but a unified method has not been determined. This makes it difficult to accurately specify the prevalence of oedema. The present s... Read More about Inter-rater reliability of the AFTD-pitting test among elderly patients in a long-term medical facility.

Effect of culture medium on propagation and phenotype of corneal stroma-derived stem cells (2015)
Journal Article
Sidney, L. E., Branch, M. J., Dua, H. S., & Hopkinson, A. (2015). Effect of culture medium on propagation and phenotype of corneal stroma-derived stem cells. Cytotherapy, 17(12), https://doi.org/10.1016/j.jcyt.2015.08.003

Background: The limbal area of the corneal stroma has been identified as a source of mesenchymal-like stem cells, which have potential for exploitation as a cell therapy. However, the optimal culture conditions are disputed and few direct media compa... Read More about Effect of culture medium on propagation and phenotype of corneal stroma-derived stem cells.

Systematic review of pre-operative exercise in colorectal cancer patients (2015)
Journal Article
Boereboom, C., Doleman, B., Lund, J. N., & Williams, J. P. (2016). Systematic review of pre-operative exercise in colorectal cancer patients. Techniques in Coloproctology, 20(2), 81-89. https://doi.org/10.1007/s10151-015-1407-1

© 2015, Springer-Verlag Italia Srl. The aim of this systematic review was to evaluate the evidence for exercise interventions prior to surgery for colorectal cancer resection. The evidence for use of exercise to improve physical fitness and surgical... Read More about Systematic review of pre-operative exercise in colorectal cancer patients.

External memory aids for memory problems in people with multiple sclerosis: A systematic review (2015)
Journal Article
Goodwin, R., Lincoln, N., das Nair, R., & Bateman, A. (in press). External memory aids for memory problems in people with multiple sclerosis: A systematic review. Neuropsychological Rehabilitation, 27(8), 1081-1102. https://doi.org/10.1080/09602011.2015.1113997

Approximately 40-60% of people with multiple sclerosis (MS) have memory problems, which adversely impact on their everyday functioning. Evidence supports the use of external memory aids in people with stroke and brain injury, and suggests they may re... Read More about External memory aids for memory problems in people with multiple sclerosis: A systematic review.

Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI (2015)
Journal Article
Hoad, C., Menys, A., Garsed, K., Marciani, L., Hamy, V., Murray, K., …Gowland, P. A. (2016). Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI. Neurogastroenterology and Motility, 28(3), 327-335. https://doi.org/10.1111/nmo.12727

Background

Recently, cine magnetic resonance imaging (MRI) has shown promise for visualizing movement of the colonic wall, although assessment of data has been subjective and observer dependent. This study aimed to develop an objective and semi-au... Read More about Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI.

Use of biochemical tests of placental function for improving pregnancy outcome (2015)
Journal Article
Heazell, A. E., Whitworth, M., Duley, L., & Thornton, J. (2015). Use of biochemical tests of placental function for improving pregnancy outcome. Cochrane Library, 2015(11), Article CD011202. https://doi.org/10.1002/14651858.CD011202.pub2

BACKGROUND:

The placenta has an essential role in determining the outcome of pregnancy. Consequently, biochemical measurement of placentally-derived factors has been suggested as a means to improve fetal and maternal outcome of pregnancy.


OBJ... Read More about Use of biochemical tests of placental function for improving pregnancy outcome.

Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells (2015)
Journal Article
Lebert-Ghali, C.-É., Fournier, M., Kettyle, L. M., Thompson, A., Sauvageau, G., & Bijl, J. J. (2016). Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. Blood, 127(1), 87-90. https://doi.org/10.1182/blood-2015-02-626390

Determination of defined roles for endogenous homeobox (Hox) genes in adult hematopoietic stem and progenitor cell (HSPC) activity has been hampered by a combination of embryonic defects and functional redundancy. Here we show that conditional homozy... Read More about Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.

Structural organization of the corpus callosum predicts attentional shifts after continuous theta burst stimulation (2015)
Journal Article
Chechlacz, M., Humphreys, G. W., Sotiropoulos, S. N., Kennard, C., & Cazzoli, D. (2015). Structural organization of the corpus callosum predicts attentional shifts after continuous theta burst stimulation. Journal of Neuroscience, 35(46), https://doi.org/10.1523/JNEUROSCI.2610-15.2015

Repetitive transcranial magnetic stimulation (rTMS) applied over the right posterior parietal cortex (PPC) in healthy participants has been shown to trigger a significant rightward shift in the spatial allocation of visual attention, temporarily mimi... Read More about Structural organization of the corpus callosum predicts attentional shifts after continuous theta burst stimulation.

A qualitative process evaluation of a randomised controlled trial of a parenting intervention in community (school) settings for children at risk of attention deficit hyperactivity disorder (ADHD) (2015)
Journal Article
Taylor, J. A., Valentine, A. Z., Sellman, E., Bransby-Adams, K., Daley, D., & Sayal, K. (2015). A qualitative process evaluation of a randomised controlled trial of a parenting intervention in community (school) settings for children at risk of attention deficit hyperactivity disorder (ADHD). BMC Psychiatry, 15(290), https://doi.org/10.1186/s12888-015-0670-z

Background: Interventions for parents of children experiencing emotional and/or behavioural difficulties can help to improve their children’s health, educational and social outcomes. However, the desirability and acceptability of screening and offeri... Read More about A qualitative process evaluation of a randomised controlled trial of a parenting intervention in community (school) settings for children at risk of attention deficit hyperactivity disorder (ADHD).

Active8! Technology-based intervention to promote physical activity in hospital employees (2015)
Journal Article
Blake, H., Suggs, L. S., Coman, E., Aguirre, L., & Batt, M. E. (2017). Active8! Technology-based intervention to promote physical activity in hospital employees. American Journal of Health Promotion, 31(2), https://doi.org/10.4278/ajhp.140415-QUAN-143

Purpose: Increase physical activity in healthcare employees using health messaging, and compare email with mobile phone short-message service (SMS) as delivery channels.
Design: Randomised controlled trial
Setting: UK hospital workplace
Subjects:... Read More about Active8! Technology-based intervention to promote physical activity in hospital employees.

Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells (2015)
Journal Article
Sidney, L. E., McIntosh, O. D., & Hopkinson, A. (2015). Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells. Investigative Ophthalmology & Visual Science, 56(12), https://doi.org/10.1167/iovs.15-17810

Purpose: Cells of the corneal epithelium and stroma can be distinguished in vivo by different intermediate filaments, cytokeratins for corneal epithelial cells (CEC) and vimentin for keratocytes. Isolated and cultured keratocytes change phenotype, lo... Read More about Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells.

Preventive acetaminophen reduces postoperative opioid consumption, vomiting, and pain scores after surgery: systematic review and meta-analysis (2015)
Journal Article
Doleman, B., Read, D., Lund, J. N., & Williams, J. P. (2015). Preventive acetaminophen reduces postoperative opioid consumption, vomiting, and pain scores after surgery: systematic review and meta-analysis. Regional Anesthesia and Pain Medicine, 40(6), https://doi.org/10.1097/AAP.0000000000000311

Background and Objectives: Preventive analgesia has been proposed as a potential strategy to reduce postoperative pain. However, there is currently no review that focuses on acetaminophen for preventive analgesia.

Methods: We conducted a search of... Read More about Preventive acetaminophen reduces postoperative opioid consumption, vomiting, and pain scores after surgery: systematic review and meta-analysis.