All Outputs (218)

Variation in composition of pre-grazed pasture herbage in the United Kingdom, 2006-2012 (2014)
Journal Article
Wilkinson, J. M., Allen, J. D., Tunnicliffe, R., Smith, M., & Garnsworthy, P. C. (2014). Variation in composition of pre-grazed pasture herbage in the United Kingdom, 2006-2012. Animal Feed Science and Technology, 196, 139-144. https://doi.org/10.1016/j.anifeedsci.2014.07.001

A total of 8814 samples of pre-grazed herbage samples was analysed by near infrared spectroscopy calibrated against wet chemistry between March 2006 and October 2012. There were decreasing trends over the seven-year period in annual mean crude protei... Read More about Variation in composition of pre-grazed pasture herbage in the United Kingdom, 2006-2012.

Evaluation of normal findings using a detailed and focused technique for transcutaneous abdominal ultrasonography in the horse (2014)
Journal Article
Williams, S., Cooper, J. D., & Freeman, S. (2014). Evaluation of normal findings using a detailed and focused technique for transcutaneous abdominal ultrasonography in the horse. BMC Veterinary Research, 10(Suppl), Article S5. https://doi.org/10.1186/1746-6148-10-S1-S5

Background

Ultrasonography is an important diagnostic tool in the investigation of abdominal disease in the horse. Several factors may affect the ability to image different structures within the abdomen. The aim of the study was to describe the re... Read More about Evaluation of normal findings using a detailed and focused technique for transcutaneous abdominal ultrasonography in the horse.

Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling (2014)
Journal Article
Barthold, J. S., Robbins, A., Wang, Y., Pugarelli, J., Mateson, A., Anand-Ivell, R., …Akins, R. E. J. (2014). Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling. Biology of Reproduction, 91(2), https://doi.org/10.1095/biolreprod.114.119560

Cryptorchidism, or undescended testis, is a common male genital anomaly of unclear etiology. Hormonal stimulation of the developing fetal gubernaculum by testicular androgens and insulin-like 3 (INSL3) is required for testicular descent. In studies o... Read More about Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling.

Variation in enteric methane emissions among cows on commercial dairy farms (2014)
Journal Article
Bell, M., Potterton, S., Craigon, J., Saunders, N., Wilcox, R., Hunter, M., …Garnsworthy, P. (2014). Variation in enteric methane emissions among cows on commercial dairy farms. Animal, 8(9), 1540-1546. https://doi.org/10.1017/S1751731114001530

Methane (CH4) emissions by dairy cows vary with feed intake and diet composition. Even when fed on the same diet at the same intake, however, variation between cows in CH4 emissions can be substantial. The extent of variation in CH4 emissions among d... Read More about Variation in enteric methane emissions among cows on commercial dairy farms.

Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice (2014)
Journal Article
Watkins, A. J., & Sinclair, K. D. (2014). Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice. AJP - Heart and Circulatory Physiology, 306(10), Article H1444-H1452. https://doi.org/10.1152/ajpheart.00981.2013

Whilst the association between maternal periconceptional diet and adult offspring health is well characterised, our understanding of the impact of paternal nutrition at the time of conception on offspring phenotype remains poorly defined. Therefore,... Read More about Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice.

Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise (2014)
Journal Article
Williams, S., Horner, J., Orton, E., Green, M. J., McMullen, S., Mobasheri, A., & Freeman, S. (2014). Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise. Equine Veterinary Journal, 47(1), https://doi.org/10.1111/evj.12238

Reasons for performing study: A change in management from pasture to stabling is a risk factor for equine colic.

Objectives: To investigate the effect of a management change from pasture with no controlled exercise to stabling with light exercise... Read More about Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise.

Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females (2014)
Journal Article
Fenton, G., Pollard, A. K., Halliday, D., Mason, R., Bredy, T. W., & Stevenson, C. W. (2014). Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females. Learning and Memory, 21(2), https://doi.org/10.1101/lm.033514.113

Anxiety disorders, such as post-traumatic stress, are more prevalent in women and are characterized by impaired inhibition of learned fear and medial prefrontal cortex (mPFC) dysfunction. Here we examined sex differences in fear extinction and mPFC a... Read More about Persistent prelimbic cortex activity contributes to enhanced learned fear expression in females.

Insulin-like factor 3 and the HPG axis in the male (2014)
Journal Article
Ivell, R., Heng, K., & Anand-Ivell, R. (in press). Insulin-like factor 3 and the HPG axis in the male. Frontiers in Endocrinology, 5(6), https://doi.org/10.3389/fendo.2014.00006

The hypothalamic–pituitary–gonadal (HPG) axis comprises pulsatile GnRH from the hypothalamus impacting on the anterior pituitary to induce expression and release of both LH and FSH into the circulation. These in turn stimulate receptors on testicular... Read More about Insulin-like factor 3 and the HPG axis in the male.

Medial prefrontal cortex circuit function during retrieval and extinction of associative learning under anesthesia (2014)
Journal Article
Fenton, G., Halliday, D., Mason, R., & Stevenson, C. W. (2014). Medial prefrontal cortex circuit function during retrieval and extinction of associative learning under anesthesia. Neuroscience, 265, https://doi.org/10.1016/j.neuroscience.2014.01.028

Associative learning is encoded under anesthesia and involves the medial prefrontal cortex (mPFC). Neuronal activity in mPFC increases in response to a conditioned stimulus (CS+) previously paired with an unconditioned stimulus (US) but not during pr... Read More about Medial prefrontal cortex circuit function during retrieval and extinction of associative learning under anesthesia.

Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study (2014)
Journal Article
Johansen, M. L., Anand-Ivell, R., Mouritsen, A., Hagen, C. P., Mieritz, M. G., Søeborg, T., …Juul, A. (2014). Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study. Reproduction, 147, https://doi.org/10.1530/REP-13-0435

Insulin-like factor 3 (INSL3) is a promising marker of Leydig cell function with potentially high clinical relevance. Limited data of INSL3 levels in relation to other reproductive hormones in healthy pubertal boys exist. In this study, we aimed to e... Read More about Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study.

A case study of the carbon footprint of milk from high-performing confinement and grass-based dairy farms (2014)
Journal Article
O'Brien, D., Capper, J., Garnsworthy, P., Grainger, C., & Shalloo, L. (2014). A case study of the carbon footprint of milk from high-performing confinement and grass-based dairy farms. Journal of Dairy Science, 97(3), https://doi.org/10.3168/jds.2013-7174

Life cycle assessment (LCA) is the preferred methodology to assess carbon footprint per unit of milk. The objective of this case study was to apply a LCA method to compare carbon footprints of high performance confinement and grass-based dairy farms.... Read More about A case study of the carbon footprint of milk from high-performing confinement and grass-based dairy farms.

Proper Application of Antibodies for Immunohistochemical Detection: Antibody Crimes and How to Prevent Them (2014)
Journal Article
Ivell, R., Teerds, K., & Hoffman, G. E. (2014). Proper Application of Antibodies for Immunohistochemical Detection: Antibody Crimes and How to Prevent Them. Endocrinology, 155(3), 676-687. https://doi.org/10.1210/en.2013-1971

For several decades antibodies raised against specific proteins, peptides, or peptide epitopes have proven to be versatile and very powerful tools to demonstrate molecular identity in cells and tissues. New techniques of immunohistochemistry and immu... Read More about Proper Application of Antibodies for Immunohistochemical Detection: Antibody Crimes and How to Prevent Them.

A survey of the awareness, knowledge, policies and views of veterinary journal Editors-in-Chief on reporting guidelines for publication of research (2014)
Journal Article
Grindlay, D. J., Dean, R. S., Christopher, M. M., & Brennan, M. L. (2014). A survey of the awareness, knowledge, policies and views of veterinary journal Editors-in-Chief on reporting guidelines for publication of research. BMC Veterinary Research, 10(1), https://doi.org/10.1186/1746-6148-10-10

Background: Wider adoption of reporting guidelines by veterinary journals could improve the quality of published veterinary research. The aims of this study were to assess the knowledge and views of veterinary Editors-in-Chief on reporting guidelines... Read More about A survey of the awareness, knowledge, policies and views of veterinary journal Editors-in-Chief on reporting guidelines for publication of research.

Insulin-like factor 3 as a monitor of endocrine disruption (2013)
Journal Article
Anand-Ivell, R., & Ivell, R. (2014). Insulin-like factor 3 as a monitor of endocrine disruption. Reproduction, 147, Article R87-R95. https://doi.org/10.1530/REP-13-0486

Insulin-like factor 3 (INSL3) is generated and secreted by differentiated interstitial Leydig cells of the testes in both fetal and adult males of all mammalian species so far analyzed. All evidence to date suggests that it is produced constitutively... Read More about Insulin-like factor 3 as a monitor of endocrine disruption.

Circulating insulin-like factor 3 (INSL3) in healthy and infertile women (2013)
Journal Article
Anand-Ivell, R., Tremellen, K., Dai, Y., Heng, K., Yosida, M., Knight, P., & Ivell, R. (2013). Circulating insulin-like factor 3 (INSL3) in healthy and infertile women. Human Reproduction, 28(11), https://doi.org/10.1093/humrep/det3

Study question: How does insulin-like factor 3 (INSL3) concentration in blood vary across the menstrual cycle in women?
Summary answer: INSL3 is secreted by the theca interna cells of growing antral follicles and is phasic in its expression.
What i... Read More about Circulating insulin-like factor 3 (INSL3) in healthy and infertile women.

Regulation of the reproductive cycle and early pregnancy by relaxin family peptides (2013)
Journal Article
Anand-Ivell, R., & Ivell, R. (2014). Regulation of the reproductive cycle and early pregnancy by relaxin family peptides. Molecular and Cellular Endocrinology, 382(1), https://doi.org/10.1016/j.mce.2013.08.010

The relaxin family of peptide hormones are structurally closely related to one another sharing a heterodimeric A–B structure, like that of insulin. They may also be active as unprocessed B–C–A pro-forms. Relaxin has been shown to pay a key role withi... Read More about Regulation of the reproductive cycle and early pregnancy by relaxin family peptides.

The effect of increasing the nutrient and amino acid concentration of milk diets on dairy heifer individual feed intake, growth, development, and lactation performance (2013)
Journal Article
Margerison, J. K., Robarts, A. D., & Reynolds, G. W. (2013). The effect of increasing the nutrient and amino acid concentration of milk diets on dairy heifer individual feed intake, growth, development, and lactation performance. Journal of Dairy Science, 96(10), 6539-6549. https://doi.org/10.3168/jds.2012-6489

Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model (2013)
Journal Article
Ivell, R., Dai, Y., Mann, N., & Anand-Ivell, R. (2014). Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model. Molecular and Cellular Endocrinology, 382(1), https://doi.org/10.1016/j.mce.2013.04.016

Steroidogenic tissues such as the ovary, testes or adrenal glands are paradoxical in that they often indicate actions of steroid hormones within a dynamic range of ligand concentration in a high nanomolar or even micromolar level, i.e. at the natural... Read More about Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model.

INSL3 as a biomarker of Leydig cell functionality (2013)
Journal Article
Ivell, R., Wade, J. D., & Anand-Ivell, R. (2013). INSL3 as a biomarker of Leydig cell functionality. Biology of Reproduction, 88(6), https://doi.org/10.1095/biolreprod.113.108969

Insulin-like factor 3 (INSL3) is a small peptide hormone made and secreted uniquely by mature Leydig cells in the testes of all mammals. Importantly, this expression and secretion appears to be constitutive and therefore reflects the differentiation... Read More about INSL3 as a biomarker of Leydig cell functionality.

Ovarian expression of Insulin-Like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles (2013)
Journal Article
Satchell, L., Glister, C., Bleach, E. C., Glencross, R. G., Bicknell, A. B., Dai, Y., …Knight, P. G. (2013). Ovarian expression of Insulin-Like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles. Endocrinology, 154(5), https://doi.org/10.1210/en.2012-2232

Insulin-like peptide 3 (INSL3), a major product of testicular Leydig cells, is also expressed by the ovary, but its functional role remains poorly understood. Here, we quantified expression of INSL3 and its receptor RXFP2 in theca interna cell (TIC)... Read More about Ovarian expression of Insulin-Like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles.