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All Outputs (53)

An observational study of centrally facilitated pain in individuals with chronic low back pain (2022)
Journal Article
Georgopoulos, V., Akin-Akinyosoye, K., Smith, S., McWilliams, D. F., Hendrick, P., & Walsh, D. A. (2022). An observational study of centrally facilitated pain in individuals with chronic low back pain. PAIN Reports, 7(3), Article e1003. https://doi.org/10.1097/PR9.0000000000001003

Central pain facilitation can hinder recovery in people with chronic low back pain (CLBP). The aim of this observational study was to investigate whether indices of centrally facilitated pain are associated with pain outcomes in a hospital-based coho... Read More about An observational study of centrally facilitated pain in individuals with chronic low back pain.

Modulating Tumour Hypoxia in Prostate Cancer Through Exercise: The Impact of Redox Signalling on Radiosensitivity (2022)
Journal Article
Brown, M., Rébillard, A., Hart, N. H., O’Connor, D., Prue, G., O’Sullivan, J. M., & Jain, S. (2022). Modulating Tumour Hypoxia in Prostate Cancer Through Exercise: The Impact of Redox Signalling on Radiosensitivity. Sports Medicine - Open, 8(1), https://doi.org/10.1186/s40798-022-00436-9

Prostate cancer is a complex disease affecting millions of men globally. Radiotherapy (RT) is a common treatment modality although treatment efficacy is dependent upon several features within the tumour microenvironment (TME), especially hypoxia. A h... Read More about Modulating Tumour Hypoxia in Prostate Cancer Through Exercise: The Impact of Redox Signalling on Radiosensitivity.

Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences (2022)
Journal Article
Nomikos, P. A., Hall, M. C., Fuller, A., Ogollah, R., Valdes, A. M., Doherty, M., Walsh, D. A., das Nair, R., & Abhishek, A. (2022). Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences. PLoS ONE, 17(1), Article e0262422. https://doi.org/10.1371/journal.pone.0262422

Objectives The overall purpose of this research programme is to develop and test the feasibility of a complex intervention for knee pain delivered by a nurse, and comprising both non-pharmacological and pharmacological interventions. In this first ph... Read More about Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences.

Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials (2021)
Journal Article
Kundakci, B., Kaur, J., Goh, S. L., Hall, M., Doherty, M., Zhang, W., & Abhishek, A. (2022). Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials. PAIN, 163(8), 1432-1445. https://doi.org/10.1097/j.pain.0000000000002500

Fibromyalgia is a highly heterogeneous condition, but the most common symptoms are widespread pain, fatigue, poor sleep, and low mood. Nonpharmacological interventions are recommended as first-line treatment of fibromyalgia. However which interventio... Read More about Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials.

Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study (2021)
Journal Article
Nomikos, P. A., Hall, M., Fuller, A., Millar, B., Ogollah, R., Valdes, A., Doherty, M., Walsh, D. A., Das Nair, R., & Abhishek, A. (2021). Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study. BMJ Open, 11(7), Article e045242. https://doi.org/10.1136/bmjopen-2020-045242

Objectives To evaluate fidelity of delivery of a nurse-led non-pharmacological complex intervention for knee pain. Setting Secondary care. Single-centre study. Study design Mixed methods study. Participants Eighteen adults with chronic knee pain. Inc... Read More about Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study.

Exploring patient experiences of cancer care in Northern Ireland: A thematic analysis of free-text responses to the 2018 Northern Ireland Patient Experience Survey (NICPES) (2021)
Journal Article
Prue, G., O’Connor, D., Brown, M., & Santin, O. (2021). Exploring patient experiences of cancer care in Northern Ireland: A thematic analysis of free-text responses to the 2018 Northern Ireland Patient Experience Survey (NICPES). BMC Health Services Research, 21, Article 564. https://doi.org/10.1186/s12913-021-06577-z

Background
Cancer diagnosis, treatment and survivorship is multifaceted, and the cancer patient experience can serve as a key indicator of healthcare performance and quality. The purpose of this paper was to analyse free-text responses from the seco... Read More about Exploring patient experiences of cancer care in Northern Ireland: A thematic analysis of free-text responses to the 2018 Northern Ireland Patient Experience Survey (NICPES).

Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study (2021)
Journal Article
Jiang, T., Yang, T., Zhang, W., Doherty, M., Zhang, Y., Wei, J., Sarmanova, A., Hall, M., Yang, Z., Li, J., Fernandes, G. S., Obotiba, A. D., Gohir, S. A., Courtney, P., Zeng, C., & Lei, G. (2021). Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study. Arthritis Research and Therapy, 23(1), Article 156. https://doi.org/10.1186/s13075-021-02539-2

Background: There is paucity of data on the prevalence of ultrasound-detected synovial abnormalities in the general population, and the relationship between synovial changes and knee pain remains unclear. We examined the prevalence of synovial abnorm... Read More about Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study.

Associations of peripheral and central pain mechanisms with voluntary muscle strength in people with knee pain (2021)
Journal Article
Yue, B., McWilliams, D., Smith, S., Stocks, J., Sarmanova, A., Fernandes, G., Swaithes, L., Frowd, N., Doherty, M., Zhang, W., Valdes, A., Hall, M., & Walsh, D. (2021). Associations of peripheral and central pain mechanisms with voluntary muscle strength in people with knee pain. Osteoarthritis and Cartilage, 29(Suppl 1), S366-S367. https://doi.org/10.1016/j.joca.2021.02.475

Impact of COVID-19 on an established physical activity and behaviour change support programme for cancer survivors: An exploratory survey of the Macmillan Move More service for Northern Ireland (2021)
Journal Article
Brown, M., O’Connor, D., Murphy, C., McClean, M., McMeekin, A., & Prue, G. (2021). Impact of COVID-19 on an established physical activity and behaviour change support programme for cancer survivors: An exploratory survey of the Macmillan Move More service for Northern Ireland. Supportive Care in Cancer, 29(10), 6135-6143. https://doi.org/10.1007/s00520-021-06165-1

Purpose
The recent coronavirus pandemic (COVID-19) has affected the delivery of routine cancer care and supportive services. The Macmillan Move More Northern Ireland (MMNI) programme provides access to physical activity and behavioural change suppor... Read More about Impact of COVID-19 on an established physical activity and behaviour change support programme for cancer survivors: An exploratory survey of the Macmillan Move More service for Northern Ireland.

Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies (2021)
Journal Article
Ayub, S., Kaur, J., Espahbodi, S., Hall, M., Doherty, M., & Zhang, W. (2021). Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies. Rheumatology, 60(4), 1629–1639. https://doi.org/10.1093/rheumatology/keaa808

Objectives
To investigate the efficacy and safety of multiple intra-articular corticosteroid (IACS) injections for the treatment of OA.

Methods
We conducted electronic searches of several databases for randomized controlled trials (RCTs) and obs... Read More about Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies.

Exercise efficacy and prescription during treatment for pancreatic ductal adenocarcinoma: a systematic review (2021)
Journal Article
O’Connor, D., Brown, M., Eatock, M., Turkington, R. C., & Prue, G. (2021). Exercise efficacy and prescription during treatment for pancreatic ductal adenocarcinoma: a systematic review. BMC Cancer, 21(1), Article 43. https://doi.org/10.1186/s12885-020-07733-0

Background: Surgical resection remains the only curative treatment for pancreatic cancer and is associated with significant post-operative morbidity and mortality. Patients eligible for surgery, increasingly receive neo-adjuvant therapy before surger... Read More about Exercise efficacy and prescription during treatment for pancreatic ductal adenocarcinoma: a systematic review.

East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol (2020)
Journal Article
Hall, M., Fuller, A., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., Greenhaff, P., Das Nair, R., Doherty, M., Walsh, D. A., & Abhishek, A. (2020). East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol. BMJ Open, 10(9), Article e037760. https://doi.org/10.1136/bmjopen-2020-037760

© 2020 BMJ Open Introduction Knee pain due to osteoarthritis (OA) is a common cause of disability. The UK National Institute for Health and Care Excellence OA guidelines recommend education, exercise and weight loss advice (if overweight) as core int... Read More about East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol.

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis (2020)
Journal Article
Jones, M., Moffatt, F., Harvey, A., & Ryan, J. M. (2020). Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2020(5), Article CD013610. https://doi.org/10.1002/14651858.cd013610

This is a protocol for a Cochrane Review (intervention). The objectives are as follows:
To assess the effects of interventions to enhance adherence to airway clearance treatment and exercise therapy in people with CF and theireffects on health outco... Read More about Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis.

Long-Term Trends in Stroke Survivors Discharged to Care Homes: The South London Stroke Register (2019)
Journal Article
Clery, A., Bhalla, A., Bisquera, A., Skolarus, L. E., Marshall, I., McKevitt, C., Rudd, A., Sackley, C., Martin, F. C., Manthorpe, J., Wolfe, C., & Wang, Y. (2020). Long-Term Trends in Stroke Survivors Discharged to Care Homes: The South London Stroke Register. Stroke, 51(1), 179-185. https://doi.org/10.1161/strokeaha.119.026618

Background and Purpose—

Care homes provide care to many stroke survivors, yet little is known about changes in care home use over time. We aim to determine trends in discharge to care homes, to explore the characteristics of stroke survivors over... Read More about Long-Term Trends in Stroke Survivors Discharged to Care Homes: The South London Stroke Register.

Neuromuscular Electrical Stimulation (NMES) in the Management of Glioblastoma Multiforme: A Case Report (2019)
Journal Article
O'Connor, D., Caulfield, B., Wright, S., & Lennon, O. (2021). Neuromuscular Electrical Stimulation (NMES) in the Management of Glioblastoma Multiforme: A Case Report. Rehabilitation Oncology, 39(2), E1-E8. https://doi.org/10.1097/01.REO.0000000000000189

Background and Purpose:
Glioblastoma multiforme (GBM) is associated with debilitating physical and psychosocial side effects. Voluntary exercise recommended as an adjunct therapy is often limited by physical and neurological impairments. The potent... Read More about Neuromuscular Electrical Stimulation (NMES) in the Management of Glioblastoma Multiforme: A Case Report.

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol (2019)
Journal Article
van Berkel, D., Ong, T., Drummond, A., Hendrick, P., Leighton, P., Jones, M., Salem, K., Quraishi, N., Brookes, C., Suazo Di Paola, A., Edwards, S., & Sahota, O. (2019). ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol. BMJ Open, 9(7), Article 032111. https://doi.org/10.1136/bmjopen-2019-032111