Cohort Profile: The Xiangya Osteoarthritis (XO) Study
(2024)
Journal Article
Li, J., Yang, T., Zhang, Y., Zhang, W., Doherty, M., Xie, J., Wang, Y., Jiang, T., Xie, D., Li, H., Yang, Z., Li, X., Li, W., Xu, B., Zhu, Z., Wang, Y., Weng, Q., Liu, K., Yang, Y., Xu, J., …Lei, G. (2024). Cohort Profile: The Xiangya Osteoarthritis (XO) Study. International Journal of Epidemiology, 53(6), Article dyae156. https://doi.org/10.1093/ije/dyae156
All Outputs (7)
Which intra-articular injection is effective and safe for osteoarthritis? (2024)
Journal Article
Zhang, W. (2025). Which intra-articular injection is effective and safe for osteoarthritis?. Osteoarthritis and Cartilage, 33(2), 189-191. https://doi.org/10.1016/j.joca.2024.11.001Intra-articular (IA) injection of corticosteroid (IACS) has been recommended for people with osteoarthritis (OA) when their pain cannot be controlled by nonsurgical treatments or when they have contraindications to oral analgesics.1,2 However, recent... Read More about Which intra-articular injection is effective and safe for osteoarthritis?.
Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials (2024)
Journal Article
Balsby, I. M., Nielsen, S. M., Christensen, R., Henriksen, M., Dahl, L. U.-M., Berg, J. I., Tarp, S., Kroon, F., Kloppenburg, M., Zhang, W., Hunter, D. J., Bliddal, H., & Døssing, A. (2024). Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials. Osteoarthritis and Cartilage, 32(7), 848-857. https://doi.org/10.1016/j.joca.2024.02.947Objective: To examine the pain relief effects of comparators (placebos and untreated control groups) in hand osteoarthritis trials and the impact of contextual factors. Methods: We systematically searched PubMed, EMBASE and CENTRAL from inception to... Read More about Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials.
Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study (2024)
Journal Article
Turnbull, J., Jha, R. R., Gowler, P. R., Ferrands-Bentley, R., Kim, D.-H., Barrett, D. A., Sarmanova, A., Fernandes, G. S., Doherty, M., Zhang, W., Walsh, D. A., Valdes, A. M., & Chapman, V. (2024). Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study. Osteoarthritis and Cartilage, 32(8), 990-1000. https://doi.org/10.1016/j.joca.2024.04.006Objective: To examine associations between serum oxylipins, which regulate tissue repair and pain signalling, and knee pain/radiographic osteoarthritis (OA) at baseline and knee pain at 3 year follow-up.
Method: Baseline, and 3 year follow-up, kne... Read More about Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study.
Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis (2024)
Journal Article
Jiang, T., Weng, Q., Zhang, Y., Zhang, W., Doherty, M., Sarmanova, A., Yang, Z., Yang, T., Li, J., Liu, K., Wang, Y., Obotiba, A. D., Zeng, C., Lei, G., & Wei, J. (2024). Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis. Arthritis Care and Research, 76(8), 1187-1194. https://doi.org/10.1002/acr.25342Objective
Although hand synovitis is prevalent in the older population, the etiology remains unclear. Hyperuricemia, a modifiable metabolic disorder, may serve as an underlying mechanism of hand synovitis, but little is known about their relationshi... Read More about Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis.
Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats (2024)
Journal Article
Li, H., Zhou, B., Wu, J., Zhang, Y., Zhang, W., Doherty, M., Deng, X., Wang, N., Xie, D., Wang, Y., Xie, H., Li, C., Wei, J., Lei, G., & Zeng, C. (2024). Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats. Journal of Pineal Research, 76(2), Article e12945. https://doi.org/10.1111/jpi.12945Melatonin exhibits potential for pain relief and long-term safety profile. We examined the analgesic effects of oral melatonin on osteoarthritis (OA) and investigated the underlying mechanism. Using data from a UK primary care database, we conducted... Read More about Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats.
Causal associations of central and peripheral risk factors with knee osteoarthritis: a longitudinal and Mendelian Randomisation study using UK Biobank data (2024)
Journal Article
Thompson, W. D., Swain, S., Zhao, S. S., Coupland, C., Kuo, C., Doherty, M., & Zhang, W. (2024). Causal associations of central and peripheral risk factors with knee osteoarthritis: a longitudinal and Mendelian Randomisation study using UK Biobank data. PAIN, 165(8), 1882-1889. https://doi.org/10.1097/j.pain.0000000000003183Our aim was to investigate relative contributions of central and peripheral mechanisms to knee osteoarthritis (OA) diagnosis and their independent causal association with knee OA. We performed longitudinal analysis using data from UK-Biobank particip... Read More about Causal associations of central and peripheral risk factors with knee osteoarthritis: a longitudinal and Mendelian Randomisation study using UK Biobank data.