Which intra-articular injection is effective and safe for osteoarthritis?

Zhang, Weiya

Abstract

Intra-articular (IA) injection of corticosteroid (IACS) has been recommended for people with osteoarthritis (OA) when their pain cannot be controlled by nonsurgical treatments or when they have contraindications to oral analgesics.1,2 However, recent randomized controlled trials (RCTs) and real-world observational studies have found that repeated IACS may be detrimental to the treated joint cartilage.3,4 Several other IA interventions have also been developed and evaluated in RCTs, including IA hyaluronic acid (IAHA), IA homeopathy (IAHP), IA platelet-rich plasma (IAPRP), and other IA autologous products.

Citation

Zhang, W. (2025). Which intra-articular injection is effective and safe for osteoarthritis?. Osteoarthritis and Cartilage, 33(2), 189-191. https://doi.org/10.1016/j.joca.2024.11.001

• Journal Article Type: Editorial
• Acceptance Date: Nov 3, 2024
• Online Publication Date: Nov 8, 2024
• Publication Date: Feb 1, 2025
• Deposit Date: Mar 6, 2025
• Journal: Osteoarthritis and Cartilage
• Print ISSN: 1063-4584
• Electronic ISSN: 1522-9653
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 33
• Issue: 2
• Pages: 189-191
• DOI: https://doi.org/10.1016/j.joca.2024.11.001
• Public URL: https://nottingham-repository.worktribe.com/output/41823832
• Publisher URL: https://www.oarsijournal.com/article/S1063-4584(24)01451-1/abstract
• Additional Information: This article is maintained by: Elsevier; Article Title: Which intra-articular injection is effective and safe for osteoarthritis?; Journal Title: Osteoarthritis and Cartilage; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.joca.2024.11.001; Content Type: simple-article; Copyright: Crown Copyright © 2024 Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International. All rights are reserved, including those for text and data mining, AI training, and similar technologies.