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Cryogenics free production of hyperpolarized 129Xe and 83Kr for biomedical MRI applications (2013)
Journal Article
Hughes-Riley, T., Six, J. S., Lilburn, D., Stupic, K. F., Dorkes, A. C., Shaw, D. E., …Meersmann, T. (2013). Cryogenics free production of hyperpolarized 129Xe and 83Kr for biomedical MRI applications. Journal of Magnetic Resonance, 237, https://doi.org/10.1016/j.jmr.2013.09.008

As an alternative to cryogenic gas handling, hyperpolarized (hp) gas mixtures were extracted directly from the spin exchange optical pumping (SEOP) process through expansion followed by compression to ambient pressure for biomedical MRI applications.... Read More about Cryogenics free production of hyperpolarized 129Xe and 83Kr for biomedical MRI applications.

Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr (2013)
Journal Article
Six, J. S., Hughes-Riley, T., Lilburn, D. M., Dorkes, A. C., Stupic, K. F., Shaw, D. E., …Meersmann, T. (2014). Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr. Magnetic Resonance Imaging, 32(1), 48-53. https://doi.org/10.1016/j.mri.2013.08.007

Hyperpolarized 83Kr has previously been demonstrated to enable MRI contrast that is sensitive to the chemical composition of the surface in a porous model system. Methodological advances have lead to a substantial increase in the 83Kr hyperpolarizati... Read More about Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr.

Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI (2013)
Journal Article
Lilburn, D. M., Hughes-Riley, T., Six, J. S., Stupic, K. F., Shaw, D. E., Pavlovskaya, G. E., & Meersmann, T. (2013). Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI. PLoS ONE, 8(8), Article e73468. https://doi.org/10.1371/journal.pone.0073468

Ex vivo rodent lung models are explored for physiological measurements of respiratory function with hyperpolarized (hp) 129Xe MRI. It is shown that excised lung models allow for simplification of the technical challenges involved and provide valuable... Read More about Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI.