All Outputs (14)

Cross-species Standardised Cortico-Subcortical Tractography (2025)
Journal Article
Assimopoulos, S., Warrington, S., Folloni, D., Bryant, K., Tang, W., Jbabdi, S., Heilbronner, S., Mars, R. B., & Sotiropoulos, S. N. (in press). Cross-species Standardised Cortico-Subcortical Tractography. eLife,

Despite their importance for brain function, cortico-subcortical white matter tracts are underrepresented in diffusion MRI tractography studies. Their non-invasive mapping is more challenging and less explored compared to other major cortico-cortical... Read More about Cross-species Standardised Cortico-Subcortical Tractography.

A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation (2025)
Journal Article
Warrington, S., Torchi, A., Mougin, O., Campbell, J., Ntata, A., Craig, M., Assimopoulos, S., Alfaro-Almagro, F., Miller, K., Jenkinson, M., Morgan, P. S., & Sotiropoulos, S. N. (2025). A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation. Scientific Data, 12, Article 609. https://doi.org/10.1038/s41597-025-04822-2

Despite its great potential for studying the living brain, magnetic resonance imaging (MRI) can be often limited by nuisance non-biological factors, such as hardware/software differences between scanners, which can interfere with biological variabili... Read More about A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation.

Connectivity Profile and Function of Uniquely Human Cortical Areas (2025)
Journal Article
Bryant, K. L., Camilleri, J., Warrington, S., Blazquez Freches, G., Sotiropoulos, S. N., Jbabdi, S., Eickhoff, S., & Mars, R. B. (2025). Connectivity Profile and Function of Uniquely Human Cortical Areas. Journal of Neuroscience, 45(15), Article e2017242025. https://doi.org/10.1523/JNEUROSCI.2017-24.2025

Determining the brain specializations unique to humans requires directly comparable anatomical information from other primates, especially our closest relatives. Human (Homo sapiens; m/f), chimpanzee (Pan troglodytes; f), and rhesus macaque (Macaca m... Read More about Connectivity Profile and Function of Uniquely Human Cortical Areas.

Connectivity profile and function of uniquely human cortical areas (2024)
Preprint / Working Paper
Bryant, K. L., Camilleri, J., Warrington, S., Blazquez Freches, G., Sotiropoulos, S. N., Jbabdi, S., Eickhoff, S., & Mars, R. B. (2024). Connectivity profile and function of uniquely human cortical areas

Quantitative comparison of the white matter organization of the human neocortex with that of the chimpanzee and macaque shows a wide distribution of areas with a uniquely human connectivity profile, including the frontal-parietal fiber systems and th... Read More about Connectivity profile and function of uniquely human cortical areas.

The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques (2024)
Preprint / Working Paper
Howell, A. M., Warrington, S., Fonteneau, C., Cho, Y. T., Sotiropoulos, S. N., Murray, J. D., & Anticevic, A. The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques

Each cortical area has a distinct pattern of anatomical connections within the thalamus, a central subcortical structure composed of functionally and structurally distinct nuclei. Previous studies have suggested that certain cortical areas may have m... Read More about The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.

Generalising XTRACT tractography protocols across common macaque brain templates (2024)
Journal Article
Assimopoulos, S., Warrington, S., Bryant, K. L., Pszczolkowski, S., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2024). Generalising XTRACT tractography protocols across common macaque brain templates. Brain Structure and Function, 229, 1873-1888. https://doi.org/10.1007/s00429-024-02760-0

Non-human primates are extensively used in neuroscience research as models of the human brain, with the rhesus macaque being a prominent example. We have previously introduced a set of tractography protocols (XTRACT) for reconstructing 42 correspondi... Read More about Generalising XTRACT tractography protocols across common macaque brain templates.

On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations (2024)
Journal Article
Helmer, M., Warrington, S., Mohammadi-Nejad, A.-R., Ji, J. L., Howell, A., Rosand, B., Anticevic, A., Sotiropoulos, S. N., & Murray, J. D. (2024). On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations. Communications Biology, 7(1), Article 217. https://doi.org/10.1038/s42003-024-05869-4

Associations between datasets can be discovered through multivariate methods like Canonical Correlation Analysis (CCA) or Partial Least Squares (PLS). A requisite property for interpretability and generalizability of CCA/PLS associations is stability... Read More about On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations.

A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches (2023)
Journal Article
Warrington, S., Ntata, A., Mougin, O., Campbell, J., Torchi, A., Craig, M., Alfaro-Almagro, F., Miller, K. L., Morgan, P. S., Jenkinson, M., & Sotiropoulos, S. N. (2023). A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches. Imaging Neuroscience, 1(2023), 1-27. https://doi.org/10.1162/imag_a_00042

Despite the huge potential of magnetic resonance imaging (MRI) in mapping and exploring the brain, MRI measures can often be limited in their consistency, reproducibility and accuracy which subsequently restricts their quantifiability. Nuisance nonbi... Read More about A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches.

QuNex – An Integrative Platform for Reproducible Neuroimaging Analytics (2023)
Journal Article
Ji, J. L., Demšar, J., Fonteneau, C., Tamayo, Z., Pan, L., Kraljič, A., Matkovič, A., Purg, N., Helmer, M., Warrington, S., Winkler, A., Zerbi, V., Coalson, T. S., Glasser, M. F., Harms, M. P., Sotiropoulos, S. N., Murray, J. D., Anticevic, A., & Repovš, G. (2023). QuNex – An Integrative Platform for Reproducible Neuroimaging Analytics. Frontiers in Neuroinformatics, 17, Article 1104508. https://doi.org/10.1101/2022.06.03.494750

Introduction: Neuroimaging technology has experienced explosive growth and transformed the study of neural mechanisms across health and disease. However, given the diversity of sophisticated tools for handling neuroimaging data, the field faces chall... Read More about QuNex – An Integrative Platform for Reproducible Neuroimaging Analytics.

Concurrent mapping of brain ontogeny and phylogeny within a common space: standardised tractography and applications (2022)
Journal Article
Warrington, S., Thompson, E., Bastiani, M., Dubois, J., Baxter, L., Slater, R., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2022). Concurrent mapping of brain ontogeny and phylogeny within a common space: standardised tractography and applications. Science Advances, 8(42), Article eabq2. https://doi.org/10.1126/sciadv.abq2022

Developmental and evolutionary effects on brain organization are complex, yet linked, as evidenced by the correspondence in cortical area expansion across these vastly different time scales. However, it is still not possible to study concurrently the... Read More about Concurrent mapping of brain ontogeny and phylogeny within a common space: standardised tractography and applications.

Predicting time-resolved electrophysiological brain networks from structural eigenmodes (2022)
Journal Article
Tewarie, P., Prasse, B., Meier, J., Mandke, K., Warrington, S., Stam, C. J., Brookes, M. J., Van Mieghem, P., Sotiropoulos, S. N., & Hillebrand, A. (2022). Predicting time-resolved electrophysiological brain networks from structural eigenmodes. Human Brain Mapping, https://doi.org/10.1002/hbm.25967

How temporal modulations in functional interactions are shaped by the underlying anatomical connections remains an open question. Here, we analyse the role of structural eigenmodes, in the formation and dissolution of temporally evolving functional b... Read More about Predicting time-resolved electrophysiological brain networks from structural eigenmodes.

Concurrent mapping of brain ontogeny and phylogeny within a common connectivity space (2022)
Preprint / Working Paper
Warrington, S., Thompson, E., Bastiani, M., Dubois, J., Baxter, L., Slater, R., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. Concurrent mapping of brain ontogeny and phylogeny within a common connectivity space

Developmental and evolutionary effects on brain organisation are complex, yet linked, as evidenced by the striking correspondence in cortical expansion changes. However, it is still not possible to study concurrently the ontogeny and phylogeny of cor... Read More about Concurrent mapping of brain ontogeny and phylogeny within a common connectivity space.

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? (2021)
Journal Article
Schilling, K. G., Rheault, F., Petit, L., Hansen, C. B., Nath, V., Yeh, F. C., Girard, G., Barakovic, M., Rafael-Patino, J., Yu, T., Fischi-Gomez, E., Pizzolato, M., Ocampo-Pineda, M., Schiavi, S., Canales-Rodríguez, E. J., Daducci, A., Granziera, C., Innocenti, G., Thiran, J. P., Mancini, L., …Descoteaux, M. (2021). Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?. NeuroImage, 243, Article 118502. https://doi.org/10.1016/j.neuroimage.2021.118502

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability i... Read More about Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?.

XTRACT - Standardised protocols for automated tractography in the human and macaque brain (2020)
Journal Article
Warrington, S., Bryant, K. L., Khrapitchev, A. A., Sallet, J., Charquero-Ballester, M., Douaud, G., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2020). XTRACT - Standardised protocols for automated tractography in the human and macaque brain. NeuroImage, 217, Article 116923. https://doi.org/10.1016/j.neuroimage.2020.116923

We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (... Read More about XTRACT - Standardised protocols for automated tractography in the human and macaque brain.